y
Basic Information | |
---|---|
Species | Citrus sinensis |
Cazyme ID | orange1.1g005796m |
Family | GT47 |
Protein Properties | Length: 678 Molecular Weight: 77000.2 Isoelectric Point: 8.4144 |
Chromosome | Chromosome/Scaffold: 00027 Start: 357947 End: 361569 |
Description | Exostosin family protein |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
GT47 | 346 | 628 | 0 |
RTLKVYVYRDGKKPIFHQPILKGLYASEGWFMKLMEGNKHFAVKDPRKAHLFYMPFSSRMLEYALYVRNSHNRTNLRQYLKEYAESIAAKYRYWNRTGGA DHFLVACHDWAPYETRHHMEHCIKALCNADVTAGFKLGRDVSLPETYVRSARNPLRDLGGKPPSQRHILAFYAGNLHGYLRPILLKYWKDKDPDMKIFGP MPPGVASKMNYIQHMKSSKYCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFYEVLNWEAFSVIIAEENIPNLKDILLSI |
Full Sequence |
---|
Protein Sequence Length: 678 Download |
MESANQFLKV FRVQTRRWLF VVLVVAVTHL LFQSLLLPYG KALRSLMPDS EVGVHDESGL 60 PALKSFSKSV MVRNPLTVNA SDLMSDSVFK GSLEDDEDSK FGSDTGDDSG LREVDGDTNN 120 GIVSEGKGQD NPIELVTDRE VDDDSVAENV KDLNDLSELE IERIGENSAT VEPAGEAKQS 180 LPLKQIVQPN LEIVSDGVPE QHTSQSIANI GGEKTLSIVS PLTNITHLKT EESNASSAAS 240 SAVPKSDIAT SVNISALIGS PGKKKMRCNM PPKTVTSIFE MNDILMRHHR SSRAMRPRWS 300 SVRDKEVLAA KTEIEKASVS VSDQELHAPL FRNVSMFKRS YELMDRTLKV YVYRDGKKPI 360 FHQPILKGLY ASEGWFMKLM EGNKHFAVKD PRKAHLFYMP FSSRMLEYAL YVRNSHNRTN 420 LRQYLKEYAE SIAAKYRYWN RTGGADHFLV ACHDWAPYET RHHMEHCIKA LCNADVTAGF 480 KLGRDVSLPE TYVRSARNPL RDLGGKPPSQ RHILAFYAGN LHGYLRPILL KYWKDKDPDM 540 KIFGPMPPGV ASKMNYIQHM KSSKYCICPK GYEVNSPRVV ESIFYECVPV IISDNFVPPF 600 YEVLNWEAFS VIIAEENIPN LKDILLSIPE KKYFEMQFAV RKLQRHFLWH AKPEKYDLFH 660 MTLHSIWYNR VYQIKPR* 720 |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-63 | 348 | 628 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 1 | 673 | 710 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 1 | 675 | 1 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 266 | 677 | 199 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 270 | 677 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 1 | 677 | 1 | 676 | catalytic, putative [Ricinus communis] |