| Basic Information | |
|---|---|
| Species | Citrus sinensis |
| Cazyme ID | orange1.1g006829m |
| Family | GH89 |
| Protein Properties | Length: 630 Molecular Weight: 71882.1 Isoelectric Point: 5.9611 |
| Chromosome | Chromosome/Scaffold: 00003 Start: 4029396 End: 4037297 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GH89 | 1 | 620 | 0 |
| MALQGINLPLAFNGQEAIWQKVFMNFNVTMEDLNDFFSGPAFLAWARMGNLHGWGGPLAQNWLNQQLVLQKKIVSRMLELGMTPVLPSFAGNVPAALKKI FPSANITRLGDWNTVDRNPRWCCTYLLDPTDPLFVEIGEAFIKQQILEYGDVTDIYNCDTFNENTPPTNDTNYISSLGAAVYKAMSEGDKDAVWLMQGWL FYSDSAFWKPPQMKALLHSVPLGKMIVLDLFAEVKPIWRTSSQFYGAPYVWCMLHNFGGNIEIYGILDSIASGPVDARVSENSTMVGVGMCMEGIEQNPV VYELMSEMAFRNEKVQVLEWLKTYAHRRYGKAVPEVEATWEILYHTVYNCTDGIADHNTDFIVKFPDWDPSLLSGSAISKRDQMHALHALPGPRRFLSEE NSDMPQAHLWYSNQELIKGLKLFLNAGNALAGCATYRYDLVDITRQALSKLANQVYMDAVIAFQHKDASAFNIHSQKFLQLIKDIDELLASNDNFLLGTW LESAKKLATNPSEMIQYEYNARTQVTMWYDTNITTQSKLHDYANKFWSGLLVDYYLPRASTYFDYMSKSLREKSEFQVDRWRQQWVFISISWQSNWKTGT KNYPIRAKGDSIAIAKVLYD | |||
| Full Sequence |
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| Protein Sequence Length: 630 Download |
| MALQGINLPL AFNGQEAIWQ KVFMNFNVTM EDLNDFFSGP AFLAWARMGN LHGWGGPLAQ 60 NWLNQQLVLQ KKIVSRMLEL GMTPVLPSFA GNVPAALKKI FPSANITRLG DWNTVDRNPR 120 WCCTYLLDPT DPLFVEIGEA FIKQQILEYG DVTDIYNCDT FNENTPPTND TNYISSLGAA 180 VYKAMSEGDK DAVWLMQGWL FYSDSAFWKP PQMKALLHSV PLGKMIVLDL FAEVKPIWRT 240 SSQFYGAPYV WCMLHNFGGN IEIYGILDSI ASGPVDARVS ENSTMVGVGM CMEGIEQNPV 300 VYELMSEMAF RNEKVQVLEW LKTYAHRRYG KAVPEVEATW EILYHTVYNC TDGIADHNTD 360 FIVKFPDWDP SLLSGSAISK RDQMHALHAL PGPRRFLSEE NSDMPQAHLW YSNQELIKGL 420 KLFLNAGNAL AGCATYRYDL VDITRQALSK LANQVYMDAV IAFQHKDASA FNIHSQKFLQ 480 LIKDIDELLA SNDNFLLGTW LESAKKLATN PSEMIQYEYN ARTQVTMWYD TNITTQSKLH 540 DYANKFWSGL LVDYYLPRAS TYFDYMSKSL REKSEFQVDR WRQQWVFISI SWQSNWKTGT 600 KNYPIRAKGD SIAIAKVLYD KYFGQQLIK* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam12972 | NAGLU_C | 6.0e-102 | 319 | 622 | 304 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| pfam05089 | NAGLU | 9.0e-168 | 1 | 314 | 314 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI24942.1 | 0 | 1 | 623 | 247 | 867 | unnamed protein product [Vitis vinifera] |
| GenBank | EEC75285.1 | 0 | 1 | 623 | 196 | 811 | hypothetical protein OsI_11626 [Oryza sativa Indica Group] |
| RefSeq | NP_196873.1 | 0 | 1 | 623 | 184 | 805 | alpha-N-acetylglucosaminidase family / NAGLU family [Arabidopsis thaliana] |
| RefSeq | XP_002273084.1 | 0 | 1 | 623 | 182 | 802 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002314048.1 | 0 | 1 | 624 | 186 | 806 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 0 | 2 | 622 | 298 | 877 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vcb_A | 0 | 2 | 622 | 298 | 877 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vca_A | 0 | 2 | 622 | 298 | 877 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| PDB | 2vc9_A | 0 | 2 | 622 | 298 | 877 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 0 | 2 | 622 | 321 | 900 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| DN960238 | 287 | 319 | 605 | 0 |
| HO783455 | 322 | 120 | 441 | 0 |
| HO783455 | 147 | 447 | 593 | 0 |
| CB611103 | 255 | 338 | 592 | 0 |
| GT627657 | 271 | 22 | 292 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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