Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g007210m |
Family | AA3 |
Protein Properties | Length: 613 Molecular Weight: 66665 Isoelectric Point: 9.4872 |
Chromosome | Chromosome/Scaffold: 00032 Start: 769398 End: 773601 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 72 | 608 | 0 |
NGDHHHHSAFDYIVVGGGTAGCPLAATLSQNFTVLLLERGGVPFSDVNVSFLQNFHMTLADTSPQSASQYFISTDGVLNARARVLGGGSSINAGFYTRAS SQFIERMGWDAKLVNESFPWVERQIVHQPKQEGWQKALRDSLLDVGVSPFNGFTYDHIYGTKIGGTIFDRFGRRHTAAELLASANPQKITVLIRATVQKI VFDTSGKRPKAVGVIFKDENGNQHQAFLAGNPKSEVILSCGAIGTPQMLKLSGVGPKAELEKLNISVVLDNAHIGKGMADNPMNAVFVPSNRPVEQSLIE TVGITKLGVYIEASSGFGESRDSIHCHHGIMSAEIGQLSTIPPKQRTPEAIQDYIRNKRTLPHEAFKGGFILEKIASPISTGELSLINTNVDDNPSVSFN YFSHPLDLKRCVDGVRMAAKIVQSKHFLNYTQCDQKSVEAILNASVRANVNLVPKHTNDTKSLEQFCKDTVITIWHYHGGCHVGKVVSTEYKVLGIDRLR VVDGSTYDESPGTNPQGTVLMMGRYMGVKILRQRLGK |
Full Sequence |
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Protein Sequence Length: 613 Download |
MDFVGALTQK PKLLFLRFLV LSLISLLSSS QAAASGAGAK NNLYKYRYPF IKEASSFTSP 60 PPPSSSSFSP RNGDHHHHSA FDYIVVGGGT AGCPLAATLS QNFTVLLLER GGVPFSDVNV 120 SFLQNFHMTL ADTSPQSASQ YFISTDGVLN ARARVLGGGS SINAGFYTRA SSQFIERMGW 180 DAKLVNESFP WVERQIVHQP KQEGWQKALR DSLLDVGVSP FNGFTYDHIY GTKIGGTIFD 240 RFGRRHTAAE LLASANPQKI TVLIRATVQK IVFDTSGKRP KAVGVIFKDE NGNQHQAFLA 300 GNPKSEVILS CGAIGTPQML KLSGVGPKAE LEKLNISVVL DNAHIGKGMA DNPMNAVFVP 360 SNRPVEQSLI ETVGITKLGV YIEASSGFGE SRDSIHCHHG IMSAEIGQLS TIPPKQRTPE 420 AIQDYIRNKR TLPHEAFKGG FILEKIASPI STGELSLINT NVDDNPSVSF NYFSHPLDLK 480 RCVDGVRMAA KIVQSKHFLN YTQCDQKSVE AILNASVRAN VNLVPKHTND TKSLEQFCKD 540 TVITIWHYHG GCHVGKVVST EYKVLGIDRL RVVDGSTYDE SPGTNPQGTV LMMGRYMGVK 600 ILRQRLGKAA GV* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam05199 | GMC_oxred_C | 3.0e-23 | 449 | 594 | 151 | + GMC oxidoreductase. This domain found associated with pfam00732. |
TIGR03970 | Rv0697 | 4.0e-24 | 82 | 594 | 573 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. |
TIGR01810 | betA | 3.0e-31 | 82 | 594 | 562 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. |
COG2303 | BetA | 7.0e-41 | 81 | 603 | 567 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] |
PLN02785 | PLN02785 | 0 | 40 | 612 | 573 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI35951.1 | 0 | 39 | 612 | 28 | 593 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002275841.1 | 0 | 34 | 612 | 14 | 584 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002327436.1 | 0 | 71 | 612 | 11 | 547 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002329018.1 | 0 | 27 | 612 | 20 | 591 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002527404.1 | 0 | 44 | 611 | 37 | 596 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 67 | 605 | 13 | 517 | B Chain B, Crystal Structure Of Plant Cell Wall Invertase In Complex With A Specific Protein Inhibitor |
PDB | 3gdp_A | 0 | 67 | 605 | 13 | 517 | B Chain B, Crystal Structure Of Plant Cell Wall Invertase In Complex With A Specific Protein Inhibitor |
PDB | 3gdn_B | 0 | 67 | 605 | 13 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 67 | 605 | 13 | 517 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 67 | 605 | 13 | 517 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |