| Basic Information | |
|---|---|
| Species | Citrus sinensis |
| Cazyme ID | orange1.1g008341m |
| Family | GH47 |
| Protein Properties | Length: 570 Molecular Weight: 64817.5 Isoelectric Point: 6.7977 |
| Chromosome | Chromosome/Scaffold: 00772 Start: 27892 End: 37897 |
| Description | alpha-mannosidase 1 |
| View CDS | |
| External Links |
|---|
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GH47 | 118 | 532 | 0 |
| AMIHAWSSYEKYAWGQDELQLLYSMCLFWRISDYSFSSEFMWIANSLDFNKSYDASVFETTIRVVGGLLSAYDLSGDKVFLEKARDIADRLLPAWNTRTG IPYNVINLAHGNPHNPSWTGGESILADSGTEQLELIALSQRTGDPKYRQKAEKVIVELNKTFPADGLLPIYISPDRGTPSYSTITFGAMGDSFYEYLLKV WIQGNKTSAVKPYRDMWETSMKGLLSLVRRSTPSSFTYICEKNGDSLIDKMDELACFAPGMIALGSSGYGPGDSEKFLSLAEELAWTCYNFYQSTPTKLA GENYFFRDGQDMSVGTSWNILRPETVESLFYLWRLTGNKTYKEWGWNIFQAFEKNSRIESGYVGLKDVNTGDKDNMMQSFFLAETLKYLYLLFSPTTVIS LDEWVFNTEAHPLKI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 570 Download |
| MARNRSSSSS SSSGKLRYCN PAYYLKRPKR LAMLLIVFVS VTLVVWDRQT LVREHEVELS 60 ELNEEVTQLR NLLEEIKNNP ANVIGKIDHI KQAKQPPGNK AFAEDPIDIQ RKQKVKDAMI 120 HAWSSYEKYA WGQDELQLLY SMCLFWRISD YSFSSEFMWI ANSLDFNKSY DASVFETTIR 180 VVGGLLSAYD LSGDKVFLEK ARDIADRLLP AWNTRTGIPY NVINLAHGNP HNPSWTGGES 240 ILADSGTEQL ELIALSQRTG DPKYRQKAEK VIVELNKTFP ADGLLPIYIS PDRGTPSYST 300 ITFGAMGDSF YEYLLKVWIQ GNKTSAVKPY RDMWETSMKG LLSLVRRSTP SSFTYICEKN 360 GDSLIDKMDE LACFAPGMIA LGSSGYGPGD SEKFLSLAEE LAWTCYNFYQ STPTKLAGEN 420 YFFRDGQDMS VGTSWNILRP ETVESLFYLW RLTGNKTYKE WGWNIFQAFE KNSRIESGYV 480 GLKDVNTGDK DNMMQSFFLA ETLKYLYLLF SPTTVISLDE WVFNTEAHPL KIVTQHDGEI 540 SGRSDGQHRP NIRLRGRKGG RFIDDIRIH* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR03897 | lanti_2_LanM | 0.005 | 181 | 279 | 108 | + type 2 lantibiotic biosynthesis protein LanM. Members of this family are known generally as LanM, a multifunctional enzyme of lantibiotic biosynthesis. This catalysis by LanM distinguishes the type 2 lantibiotics, such as mersacidin, cinnamycin, and lichenicidin, from LanBC-produced type 1 lantibiotics such as nisin and subtilin. The N-terminal domain contains regions associated with Ser and Thr dehydration. The C-terminal region contains a pfam05147 domain, which catalyzes the formation of the lanthionine bridge [Cellular processes, Toxin production and resistance]. | ||
| COG1331 | COG1331 | 0.0002 | 180 | 272 | 93 | + Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones] | ||
| PTZ00470 | PTZ00470 | 8.0e-174 | 77 | 532 | 493 | + glycoside hydrolase family 47 protein; Provisional | ||
| pfam01532 | Glyco_hydro_47 | 8.0e-177 | 118 | 532 | 452 | + Glycosyl hydrolase family 47. Members of this family are alpha-mannosidases that catalyze the hydrolysis of the terminal 1,2-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
| GO:0005509 | calcium ion binding |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF16414.1 | 0 | 15 | 561 | 14 | 576 | AF126550_1 mannosyl-oligosaccharide 1,2-alpha-mannosidase [Glycine max] |
| EMBL | CBI18472.1 | 0 | 1 | 565 | 1 | 575 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_175570.1 | 0 | 1 | 564 | 1 | 559 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| RefSeq | NP_566675.1 | 0 | 1 | 561 | 1 | 568 | mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002310939.1 | 0 | 1 | 519 | 1 | 524 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1nxc_A | 0 | 110 | 543 | 19 | 476 | A Chain A, Structure Of Mouse Golgi Alpha-1,2-Mannosidase Ia Reveals The Molecular Basis For Substrate Specificity Among Class I Enzymes (Family 47 Glycosidases) |
| PDB | 1fmi_A | 0 | 103 | 534 | 1 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo3_A | 0 | 103 | 534 | 1 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase |
| PDB | 1fo2_A | 0 | 103 | 534 | 1 | 458 | A Chain A, Crystal Structure Of Human Class I Alpha1,2-Mannosidase In Complex With 1-Deoxymannojirimycin |
| PDB | 1x9d_A | 0 | 106 | 534 | 82 | 536 | A Chain A, Crystal Structure Of Human Class I Alpha-1,2-Mannosidase In Complex With Thio-Disaccharide Substrate Analogue |
| Hydropathy |
|---|
 |
| EST Download unfiltered results here | ||||
|---|---|---|---|---|
 | ||||
| Hit | Length | Start | End | EValue |
| CU615093 | 325 | 241 | 565 | 0 |
| HO780776 | 522 | 23 | 499 | 0 |
| DY974119 | 307 | 162 | 468 | 0 |
| GW895275 | 284 | 237 | 519 | 0 |
| HO780776 | 72 | 490 | 561 | 3e-21 |
| Sequence Alignments (This image is cropped. Click for full image.) |
|---|
 |
