Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g009454m |
Family | GT47 |
Protein Properties | Length: 535 Molecular Weight: 62186.5 Isoelectric Point: 9.9273 |
Chromosome | Chromosome/Scaffold: 00053 Start: 210812 End: 217453 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 197 | 482 | 0 |
TLRVYIYSNGKRPIFHHPYLRGIYASEGWFMKLMRGNKHFVTEDPEKAHLFYLPYSVRQLQLALYVPNSHSMKPLTNFLRDYVNMIAAKYPFWNRTHGSD HFFVACHDWGPYTTVAHTELKENAIKVLCNADLSEGIFVAGKDVSLPETTIKFPKKPQRHIGGGNRVSQRPILAFFAGYMHGRVRPILLKYWKDDEDMKI YRRLPHLVSKEMSYIQHMKSSRYCICPMGYEVNSPRIVEAIYYECVPVIIADNFVLPFSEVLDWSAFSVVIPEKDIPKLKEILLAI |
Full Sequence |
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Protein Sequence Length: 535 Download |
MQKKHRSRNS QSLFLMKELF LWCVRLRMNS RKLIFAGAMT TVAAALLHLW FLSHPLTVSS 60 YNSLNGSMRP SQLSETLQEP RIYRIQHLPA NSIISQNSSI EVMQSVPVEG RAGDSNGKRW 120 KTDDKSKVIP TPPPPPPRSP TLSLQRYIWT LTPIEALLFA KKEIDHAPII TEDAELYAPL 180 FRNISVFKRS YELMEMTLRV YIYSNGKRPI FHHPYLRGIY ASEGWFMKLM RGNKHFVTED 240 PEKAHLFYLP YSVRQLQLAL YVPNSHSMKP LTNFLRDYVN MIAAKYPFWN RTHGSDHFFV 300 ACHDWGPYTT VAHTELKENA IKVLCNADLS EGIFVAGKDV SLPETTIKFP KKPQRHIGGG 360 NRVSQRPILA FFAGYMHGRV RPILLKYWKD DEDMKIYRRL PHLVSKEMSY IQHMKSSRYC 420 ICPMGYEVNS PRIVEAIYYE CVPVIIADNF VLPFSEVLDW SAFSVVIPEK DIPKLKEILL 480 AIPLRKYLEM QVNVKMVQKH FVWHPVPIKY DLFHMVLHSI WFNRLNQIQD PQSH* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-72 | 198 | 482 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI23466.1 | 0 | 27 | 529 | 15 | 534 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 16 | 529 | 16 | 532 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 27 | 529 | 15 | 534 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002303362.1 | 0 | 149 | 533 | 1 | 386 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530666.1 | 0 | 15 | 533 | 1 | 528 | catalytic, putative [Ricinus communis] |