Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g011757m |
Family | GT47 |
Protein Properties | Length: 479 Molecular Weight: 54631.6 Isoelectric Point: 9.2833 |
Chromosome | Chromosome/Scaffold: 00002 Start: 1531542 End: 1533572 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 58 | 402 | 0 |
SIKVYVADLPRSYNYGLIDQYWASTSPDSRLPSDPDHQTPHPHPPNRYPENPLIKQYSAEYWIMGDLETPQNLRTNSFAKRVFDANEADVVFVPFFATLS AEMELAKAKQKNMFRKKGDGNEDYKRQKEVIDFVINSDPWKRSGGRDHVFVLTDPVAMWHVRSQIAPAILLVVDFGGWYRLDSKSSNGNSSEMIQHTQVS LLKDVIVPYTHLLPRLYLSDNKKRQNLLYFKGAKHRHRGGVVREKLWDLLVNEAGVIMEEGFPNATGREQSIKGMRSSEFCLHPAGDTPTSCRLFDAIQS LCIPVIVSDNIELPFEGMVDYFEFSVFVALRDALTPNWLVRHLRS |
Full Sequence |
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Protein Sequence Length: 479 Download |
MATMKKYHYT SKWSICLSLT LLSIVSLSFF FFITANKNPT SSASSDHQLR IQTSNPNSIK 60 VYVADLPRSY NYGLIDQYWA STSPDSRLPS DPDHQTPHPH PPNRYPENPL IKQYSAEYWI 120 MGDLETPQNL RTNSFAKRVF DANEADVVFV PFFATLSAEM ELAKAKQKNM FRKKGDGNED 180 YKRQKEVIDF VINSDPWKRS GGRDHVFVLT DPVAMWHVRS QIAPAILLVV DFGGWYRLDS 240 KSSNGNSSEM IQHTQVSLLK DVIVPYTHLL PRLYLSDNKK RQNLLYFKGA KHRHRGGVVR 300 EKLWDLLVNE AGVIMEEGFP NATGREQSIK GMRSSEFCLH PAGDTPTSCR LFDAIQSLCI 360 PVIVSDNIEL PFEGMVDYFE FSVFVALRDA LTPNWLVRHL RSFSEEQKDK FRHRMAEIQP 420 IFVYENNHPG GIGPILPDGA VNHVWKKVHQ KLPMIKEAIV RAKRKPPGVS IPLRCHCT* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-60 | 56 | 403 | 361 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_564443.1 | 0 | 57 | 477 | 55 | 476 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270238.1 | 0 | 19 | 478 | 25 | 440 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325567.1 | 0 | 14 | 478 | 17 | 476 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002327326.1 | 0 | 25 | 478 | 1 | 449 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002533317.1 | 0 | 57 | 478 | 53 | 478 | catalytic, putative [Ricinus communis] |