| Basic Information | |
|---|---|
| Species | Citrus sinensis |
| Cazyme ID | orange1.1g012707m |
| Family | AA3 |
| Protein Properties | Length: 459 Molecular Weight: 50050.4 Isoelectric Point: 7.4422 |
| Chromosome | Chromosome/Scaffold: 00040 Start: 351714 End: 355374 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| AA3 | 33 | 451 | 2.60642e-43 |
| WDERLVNESYQWVEKVVAFEPPMRQWQSAVRDGLVEVGVLPYNGFTYDHMYGTKIGGTIFDQNGQRHTAADLLEYANPSGLTLLLHASVHKVLFRIKGKA RPVAHGVVFRDATGAKHRAYLKNGPKNEIIVSAGALGSPQLLMLSGAHNITVVLDQPLVGQGMSDNPMNAIFVPSPVPVEVSLIQVVGITQFGSYIEAAS GENFAGGSPSPRDYGMFSPKIGQLSKVPPKQRTPEAIAEAIENMKALDDPAFRGGFILEKVMGPVSTGHLELRTRNPNDNPSVTFNYFKEPEDLQRCVQG ISTIEKIIESKSFSKFKYESMSVPILVNMTASAPVNLLPRHSNASTSLEQFCRDTVMTIWHYHGGCQVGKVVDHDYKVLGVDALRVIDGSTFYYSPGTNP QATVMMLGRYMGVRILSER | |||
| Full Sequence |
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| Protein Sequence Length: 459 Download |
| MASSIPVPAF WEVAVASMPA STHALLLIMS VGWDERLVNE SYQWVEKVVA FEPPMRQWQS 60 AVRDGLVEVG VLPYNGFTYD HMYGTKIGGT IFDQNGQRHT AADLLEYANP SGLTLLLHAS 120 VHKVLFRIKG KARPVAHGVV FRDATGAKHR AYLKNGPKNE IIVSAGALGS PQLLMLSGAH 180 NITVVLDQPL VGQGMSDNPM NAIFVPSPVP VEVSLIQVVG ITQFGSYIEA ASGENFAGGS 240 PSPRDYGMFS PKIGQLSKVP PKQRTPEAIA EAIENMKALD DPAFRGGFIL EKVMGPVSTG 300 HLELRTRNPN DNPSVTFNYF KEPEDLQRCV QGISTIEKII ESKSFSKFKY ESMSVPILVN 360 MTASAPVNLL PRHSNASTSL EQFCRDTVMT IWHYHGGCQV GKVVDHDYKV LGVDALRVID 420 GSTFYYSPGT NPQATVMMLG RYMGVRILSE RLASNDSK* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 1.0e-12 | 95 | 197 | 115 | + choline dehydrogenase; Validated | ||
| TIGR01810 | betA | 1.0e-13 | 74 | 440 | 398 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| pfam05199 | GMC_oxred_C | 3.0e-22 | 296 | 440 | 150 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
| COG2303 | BetA | 5.0e-24 | 95 | 455 | 382 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 0 | 28 | 452 | 435 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI34759.1 | 0 | 28 | 458 | 141 | 578 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_001053612.1 | 0 | 28 | 454 | 143 | 583 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002282510.1 | 0 | 28 | 458 | 107 | 544 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298074.1 | 0 | 28 | 456 | 140 | 574 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002509694.1 | 0 | 28 | 458 | 144 | 548 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ju2_B | 0 | 31 | 455 | 127 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 1ju2_A | 0 | 31 | 455 | 127 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_B | 0 | 31 | 455 | 127 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 31 | 455 | 127 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 31 | 455 | 127 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX672181 | 271 | 179 | 449 | 0 |
| HO796743 | 435 | 27 | 451 | 0 |
| HO799688 | 298 | 165 | 454 | 0 |
| DT561858 | 311 | 28 | 330 | 0 |
| CV709380 | 239 | 221 | 459 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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