Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g013815m |
Family | GT47 |
Protein Properties | Length: 437 Molecular Weight: 49444.7 Isoelectric Point: 8.3523 |
Chromosome | Chromosome/Scaffold: 00005 Start: 792696 End: 796069 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 169 | 387 | 0 |
LIQYLRNYVNLISAKHNFWNRTEGADHFLVACHDWAPAETRIIMANCIRALCNSDVKEGFVFGKDVALPETYVLSPQNPLRAIGGKPASQRSILAFFAGR MHGYLRPILLHHWENKDPDMKIFGQMPMVKGKGKGKGKGKRKGKMDYIQHMKSSKYCICAKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEILNWESF AVFVLEKDIPNLKNILLSI |
Full Sequence |
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Protein Sequence Length: 437 Download |
MGYEIRSLFQ GETKRLLWLM GIMLTVIVAF QYFELPYDHV LSSVFSTGKV PAPAVENNSL 60 VTGGLESKSE IASDAVNGLN STGTHNVHEM ANDTRTSKAE DANLQADFDD GEDIHEEPTN 120 EKLEGLNKNS TVDTVQNAGN VPGPEKGRES EQSFIQRNDI MGGDSGGNLI QYLRNYVNLI 180 SAKHNFWNRT EGADHFLVAC HDWAPAETRI IMANCIRALC NSDVKEGFVF GKDVALPETY 240 VLSPQNPLRA IGGKPASQRS ILAFFAGRMH GYLRPILLHH WENKDPDMKI FGQMPMVKGK 300 GKGKGKGKRK GKMDYIQHMK SSKYCICAKG YEVNSPRVVE AIFYECVPVI ISDNFVPPFF 360 EILNWESFAV FVLEKDIPNL KNILLSISEK RYRRMQMRVK KVQQHFLWHP QPVKYDIFHM 420 LLHSIWYNRV FLARAR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-52 | 165 | 387 | 238 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42936.1 | 0 | 162 | 431 | 10 | 268 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 1e-16 | 1 | 223 | 1 | 211 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 165 | 436 | 409 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 160 | 436 | 205 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 160 | 436 | 132 | 398 | predicted protein [Populus trichocarpa] |