Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g015235m |
Family | GT47 |
Protein Properties | Length: 412 Molecular Weight: 47580.6 Isoelectric Point: 9.2916 |
Chromosome | Chromosome/Scaffold: 00059 Start: 48472 End: 51404 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 88 | 363 | 0 |
NFKIYIYPDGDPNTFYQTPRKLTGKYASEGYFFQNIRESRFLTHDPDRAHLFFIPISCHKMRGKGTSYENMTVIVKDYVDSLINKYPYWNRTLGADHFFV TCHDVGVRATEGVPFLIKNAIRVVCSPSYDVAFIPHKDVALPQVLQPFALPRGGRDVENRTVLGFWAGHRNSKIRVILARVWENDTELDISNNRINRAIG PLVYQRRFYKTKFCICPGGSQVNSARIADSIHYGCVPVILSNYYDLPFNDILDWRKFAVILNERDVYQLKQILKNI |
Full Sequence |
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Protein Sequence Length: 412 Download |
MIGSKAAQPN QAQTTLCSLR SSLLTLALVT LLCFTCLSFN SFRSYPLQNN FNSTLSFAIN 60 KQDYSDLGSD VFHSPSVFHL NYLEMVTNFK IYIYPDGDPN TFYQTPRKLT GKYASEGYFF 120 QNIRESRFLT HDPDRAHLFF IPISCHKMRG KGTSYENMTV IVKDYVDSLI NKYPYWNRTL 180 GADHFFVTCH DVGVRATEGV PFLIKNAIRV VCSPSYDVAF IPHKDVALPQ VLQPFALPRG 240 GRDVENRTVL GFWAGHRNSK IRVILARVWE NDTELDISNN RINRAIGPLV YQRRFYKTKF 300 CICPGGSQVN SARIADSIHY GCVPVILSNY YDLPFNDILD WRKFAVILNE RDVYQLKQIL 360 KNISDAEFVS LHNNLVKVQK HFQWNSPPVR FDAFHMVMYE LWLRRHVIKY F* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-56 | 89 | 363 | 294 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ACU18220.1 | 0 | 70 | 410 | 69 | 409 | unknown [Glycine max] |
RefSeq | NP_195517.1 | 0 | 12 | 410 | 15 | 425 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002266299.1 | 0 | 1 | 410 | 1 | 416 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002307304.1 | 0 | 16 | 410 | 1 | 406 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522880.1 | 0 | 59 | 410 | 55 | 406 | catalytic, putative [Ricinus communis] |