Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g025504m |
Family | GT47 |
Protein Properties | Length: 253 Molecular Weight: 29362.4 Isoelectric Point: 10.082 |
Chromosome | Chromosome/Scaffold: 00005 Start: 807775 End: 809086 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 2 | 203 | 0 |
ISAKHNFWNRTEGADHFLVACHDWAPAETRIIMANCIRALCNSDVKQGFVFGKDVSLPETNVLSPQNPLWAIGGKPASQRSILAFFAGSMHGYLRPILLH HWENKDPDMKIFGQMPKAKGRGKRKGKTDYIQHMKSSKYCICAKGYEVHSPRVVEAIFYECVPVIISDNFVPPFFEILNWESFAVFVLERDIPNLKNILL SI |
Full Sequence |
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Protein Sequence Length: 253 Download |
MISAKHNFWN RTEGADHFLV ACHDWAPAET RIIMANCIRA LCNSDVKQGF VFGKDVSLPE 60 TNVLSPQNPL WAIGGKPASQ RSILAFFAGS MHGYLRPILL HHWENKDPDM KIFGQMPKAK 120 GRGKRKGKTD YIQHMKSSKY CICAKGYEVH SPRVVEAIFY ECVPVIISDN FVPPFFEILN 180 WESFAVFVLE RDIPNLKNIL LSISEKRYRK MQMMVKKVQQ HFLWHPRPVK YDIFHMILHS 240 IWYNRVFLAR AR* |
Functional Domains Download unfiltered results here | ||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
pfam03016 | Exostosin | 6.0e-49 | 1 | 203 | 216 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42936.1 | 0 | 1 | 247 | 27 | 268 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_195005.1 | 0 | 1 | 247 | 350 | 591 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 252 | 423 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 1 | 252 | 224 | 471 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 1 | 252 | 151 | 398 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DT214477 | 252 | 8 | 253 | 0 |
EY690253 | 248 | 11 | 252 | 0 |
EY695868 | 221 | 28 | 248 | 0 |
EY840257 | 228 | 30 | 253 | 0 |
DT739417 | 251 | 3 | 253 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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