Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g038832m |
Family | GT47 |
Protein Properties | Length: 338 Molecular Weight: 39786.7 Isoelectric Point: 8.6219 |
Chromosome | Chromosome/Scaffold: 00051 Start: 614217 End: 615524 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 2 | 285 | 0 |
EKRFRVWAYKEGEQPLFHRGPMNDIYSIEGQFIDELESDKSPFAASHPDDAVAYFIPVSIVNIIRYVYRPYTDYSRKRLQNIVKDYIDLISSRYPYWNRS NGADHFFVSCHDWAPEVSAAHPTFYKHFIRVLCNANSSEGFHPVKDVSMPEIYLKRRILRPPQLSQASNNRSILAFFAGGPHGFVRELLFRYWKHKDDDI QVHEYLPQTLNYTQLMGQSKFCLCPSGYEVASPRLVESIYSACVPVIISDHYVLPFSDVLDWRQFSVHIPVEKIPEIKKILQGI |
Full Sequence |
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Protein Sequence Length: 338 Download |
MEKRFRVWAY KEGEQPLFHR GPMNDIYSIE GQFIDELESD KSPFAASHPD DAVAYFIPVS 60 IVNIIRYVYR PYTDYSRKRL QNIVKDYIDL ISSRYPYWNR SNGADHFFVS CHDWAPEVSA 120 AHPTFYKHFI RVLCNANSSE GFHPVKDVSM PEIYLKRRIL RPPQLSQASN NRSILAFFAG 180 GPHGFVRELL FRYWKHKDDD IQVHEYLPQT LNYTQLMGQS KFCLCPSGYE VASPRLVESI 240 YSACVPVIIS DHYVLPFSDV LDWRQFSVHI PVEKIPEIKK ILQGISVEEY LEKQKRVVQV 300 QRHFLMNRPA KPFDLMHMVM HSVWLRRLNI RLHELQY* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-56 | 1 | 285 | 303 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21065.1 | 0 | 1 | 332 | 66 | 400 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_196674.1 | 0 | 1 | 332 | 1 | 332 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285239.1 | 0 | 1 | 332 | 1 | 335 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324873.1 | 0 | 1 | 332 | 1 | 333 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515488.1 | 0 | 1 | 335 | 137 | 471 | catalytic, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC939466 | 238 | 1 | 233 | 0 |
GE475605 | 300 | 39 | 334 | 0 |
FD507587 | 225 | 44 | 268 | 0 |
GO373511 | 258 | 80 | 337 | 0 |
FE523338 | 267 | 1 | 266 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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