Basic Information | |
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Species | Citrus sinensis |
Cazyme ID | orange1.1g045909m |
Family | GT47 |
Protein Properties | Length: 269 Molecular Weight: 30795.1 Isoelectric Point: 8.5896 |
Chromosome | Chromosome/Scaffold: 00013 Start: 382988 End: 383907 |
Description | Exostosin family protein |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 139 | 254 | 2.4e-34 |
KKFKVWIYKEGEHPTVHIGPMHNKYAIEGQFIDEMESKNNPFRASHPDEAHAFFLPFSVANVVQYVYQPITTVKDYSRDRLQRLLTDYVTVVADKYPYWN RSNGADHFMVSCHDWV |
Full Sequence |
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Protein Sequence Length: 269 Download |
METLGCNISL LLLQAFLLFL ILSLTFSSPF TEKHVDVASF FSTFETRNVR VAQFFINASS 60 SPPQVSSSNF SLATALYNSS INKFYKARSI RVEEDLAQAR AAIRKAIHLQ NYTSHSHRTE 120 TFIPTGSIYK NASHTEMVKK FKVWIYKEGE HPTVHIGPMH NKYAIEGQFI DEMESKNNPF 180 RASHPDEAHA FFLPFSVANV VQYVYQPITT VKDYSRDRLQ RLLTDYVTVV ADKYPYWNRS 240 NGADHFMVSC HDWVSTYIYV LLNLLLPL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-15 | 137 | 259 | 130 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03873.1 | 0 | 78 | 253 | 227 | 395 | Exostosin-like [Medicago truncatula] |
EMBL | CBI25537.1 | 0 | 38 | 259 | 40 | 263 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197526.4 | 0 | 65 | 253 | 5 | 188 | catalytic [Arabidopsis thaliana] |
Swiss-Prot | Q3E9A4 | 0 | 55 | 253 | 43 | 246 | GLYT5_ARATH RecName: Full=Probable glycosyltransferase At5g20260 |
RefSeq | XP_002263848.1 | 0 | 86 | 259 | 4 | 182 | PREDICTED: hypothetical protein [Vitis vinifera] |