Basic Information | |
---|---|
Species | Citrus sinensis |
Cazyme ID | orange1.1g047215m |
Family | CBM57 |
Protein Properties | Length: 852 Molecular Weight: 94656.1 Isoelectric Point: 5.573 |
Chromosome | Chromosome/Scaffold: 00010 Start: 185117 End: 187672 |
Description | hercules receptor kinase 2 |
View CDS |
External Links |
---|
CAZyDB |
Signature Domain Download full data set without filtering | |||
---|---|---|---|
Family | Start | End | Evalue |
CBM57 | 221 | 375 | 3.6e-22 |
YRLNVGGPEIKPSRDPDLWRMWEADSSYMITANAGSEIRNSSNITYASTNDSSVAPLLVYETARTMSNTEVLEKRFNMSWKFEVDPNFDYFVRLHFCELV YEKANQRIFRIYINNRTAENNFDIFVQAGGKNRGYHRDYFDAVSSKIETLWIQLG |
Full Sequence |
---|
Protein Sequence Length: 852 Download |
MERVLLFLVI MLVVARIGEA QSKSFLINCG TNSSVNVDGR KWVGDLASNN NVTLSSSGIA 60 ATTDSLSGDS IYEPLYKTAR VFADGLNYTF EIIAGNYIVR LHFCPFPFED YNVNKSSFGV 120 VANGLKLLSE FSAPGEISHR NLYLQSSGGN SSSISLVKEY FLGVDLDKLM IEFIPSKGSF 180 GFINAIEIVP VVDKLFADTI NKVGGNDVNF NLSGRGVETM YRLNVGGPEI KPSRDPDLWR 240 MWEADSSYMI TANAGSEIRN SSNITYASTN DSSVAPLLVY ETARTMSNTE VLEKRFNMSW 300 KFEVDPNFDY FVRLHFCELV YEKANQRIFR IYINNRTAEN NFDIFVQAGG KNRGYHRDYF 360 DAVSSKIETL WIQLGPDTAV GAAGTDALLN GLEIFKFSQN GNLASVERFD SSGNPVGHSN 420 KWILLVGIGA GIASVVVLAV IFALLFCYCK NWREKSSDPK NNSPGWWPLF FHRGTLNSTA 480 NAKGSGTQYL KGSVALTRAG KRFTLAEIRV ATNNFDESLM IGVGGFGKVF KGEIEDCTLA 540 AIKRANPQSE QGLAEFETEI EMLSKLRHRH LVSLIGFCDE QNEMILVYEY MANGTLRSHL 600 FGSDLPPLTW KQRLDACIGA ARGLHYLHTG AERGIIHRDV KTTNILLDEN FVAKMSDFGL 660 SKTGPSMEHT HVSTAVKGSF GYLDPEYFWR QQLTEKSDVY SFGVVLFEVV CARAVINPTL 720 PKDQINLADW AMKWQKQRSL KSIIDPHLKG NYSPESLEKF GEIAEKCLDD EGKNRPTMGE 780 VLWHLEYVLQ LHEAWMRTDD RQNSFSSSQA LGEFAEREAE DGQDAPTTDA ENCLGLKMTG 840 EVESATMGIS K* |
Functional Domains Download unfiltered results here | ||||||||
---|---|---|---|---|---|---|---|---|
Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam07714 | Pkinase_Tyr | 1.0e-42 | 536 | 711 | 177 | + Protein tyrosine kinase. | ||
smart00219 | TyrKc | 1.0e-43 | 541 | 785 | 252 | + Tyrosine kinase, catalytic domain. Phosphotransferases. Tyrosine-specific kinase subfamily. | ||
smart00221 | STYKc | 9.0e-44 | 541 | 785 | 252 | + Protein kinase; unclassified specificity. Phosphotransferases. The specificity of this class of kinases can not be predicted. Possible dual-specificity Ser/Thr/Tyr kinase. | ||
cd00192 | PTKc | 2.0e-45 | 538 | 786 | 259 | + Catalytic domain of Protein Tyrosine Kinases. Protein Tyrosine Kinase (PTK) family, catalytic domain. This PTKc family is part of a larger superfamily that includes the catalytic domains of protein serine/threonine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase (PI3K). PTKs catalyze the transfer of the gamma-phosphoryl group from ATP to tyrosine (tyr) residues in protein substrates. They can be classified into receptor and non-receptor tyr kinases. PTKs play important roles in many cellular processes including, lymphocyte activation, epithelium growth and maintenance, metabolism control, organogenesis regulation, survival, proliferation, differentiation, migration, adhesion, motility, and morphogenesis. Receptor tyr kinases (RTKs) are integral membrane proteins which contain an extracellular ligand-binding region, a transmembrane segment, and an intracellular tyr kinase domain. RTKs are usually activated through ligand binding, which causes dimerization and autophosphorylation of the intracellular tyr kinase catalytic domain, leading to intracellular signaling. Some RTKs are orphan receptors with no known ligands. Non-receptor (or cytoplasmic) tyr kinases are distributed in different intracellular compartments and are usually multi-domain proteins containing a catalytic tyr kinase domain as well as various regulatory domains such as SH3 and SH2. PTKs are usually autoinhibited and require a mechanism for activation. In many PTKs, the phosphorylation of tyr residues in the activation loop is essential for optimal activity. Aberrant expression of PTKs is associated with many development abnormalities and cancers. | ||
pfam12819 | Malectin_like | 5.0e-61 | 27 | 396 | 382 | + Carbohydrate-binding protein of the ER. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognises and binds Glc2-N-glycan. The domain is found on a number of plant receptor kinases. |
Gene Ontology | |
---|---|
GO Term | Description |
GO:0004672 | protein kinase activity |
GO:0005524 | ATP binding |
GO:0006468 | protein phosphorylation |
Annotations - NR Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI31024.1 | 0 | 1 | 850 | 1 | 843 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002264211.1 | 0 | 1 | 850 | 46 | 888 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002299052.1 | 0 | 5 | 840 | 12 | 840 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002330599.1 | 0 | 5 | 826 | 12 | 832 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523186.1 | 0 | 5 | 831 | 12 | 834 | kinase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
---|---|---|---|---|---|---|---|
Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 2qkw_B | 0 | 502 | 794 | 28 | 319 | A Chain A, Structural Basis For Activation Of Plant Immunity By Bacterial Effector Protein Avrpto |
PDB | 3hgk_D | 0 | 502 | 794 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_C | 0 | 502 | 794 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_B | 0 | 502 | 794 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
PDB | 3hgk_A | 0 | 502 | 794 | 28 | 319 | E Chain E, Crystal Structure Of Effect Protein Avrptob Complexed With Kinase Pto |
Transmembrane Domains | ||||
---|---|---|---|---|
Start | End | |||
424 | 446 |
Signal Peptide | ||||
---|---|---|---|---|
Cleavage Site | ||||
20 |
EST Download unfiltered results here | ||||
---|---|---|---|---|
Hit | Length | Start | End | EValue |
ES805185 | 340 | 447 | 781 | 0 |
GH270923 | 253 | 580 | 832 | 0 |
ES793081 | 251 | 571 | 821 | 0 |
EX357602 | 246 | 536 | 781 | 0 |
JG961928 | 270 | 538 | 807 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
---|