| Basic Information | |
|---|---|
| Species | Prunus persica |
| Cazyme ID | ppa001048m |
| Family | GT20 |
| Protein Properties | Length: 925 Molecular Weight: 104374 Isoelectric Point: 6.8199 |
| Chromosome | Chromosome/Scaffold: 4 Start: 8916224 End: 8922540 |
| Description | trehalose-6-phosphate synthase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 82 | 553 | 0 |
| PLRQRQRLLVVANRLPVSAVRRGEDSWSLDISAGGLVSALLGVKEFEARWIGWAGVNVPDEIGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWP LFHYLGLPQEDRLATTRSFQSQFAAYKKANQMFADVVNEHYLEGDVVWCHDYHLMFLPKCLKDYNSKMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAA DLVGFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSERFIRALEVPQVQEHIRELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKF LEENPSWRDKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEFVACQDAKKG VLILSEFAGAAQSLGAGAILVNPWNITEVANSIAQALNMASEEREKRHKHNFIHVTTHTAQEWAETFVSELN | |||
| Full Sequence |
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| Protein Sequence Length: 925 Download |
| MPGDKYNSNS SHIPNRVERL LRERELRKNS RASHLNEAQP FEPDLQLRED ENSKVAYVEQ 60 FLEGAAAARA LTDGCEKQEG RPLRQRQRLL VVANRLPVSA VRRGEDSWSL DISAGGLVSA 120 LLGVKEFEAR WIGWAGVNVP DEIGQKALTK ALAEKRCIPV FLDEEIVHQY YNGYCNNILW 180 PLFHYLGLPQ EDRLATTRSF QSQFAAYKKA NQMFADVVNE HYLEGDVVWC HDYHLMFLPK 240 CLKDYNSKMK VGWFLHTPFP SSEIHRTLPS RSELLRSVLA ADLVGFHTYD YARHFVSACT 300 RILGLEGTPE GVEDQGRLTR VAAFPIGIDS ERFIRALEVP QVQEHIRELK ERFAGRKVML 360 GVDRLDMIKG IPQKILAFEK FLEENPSWRD KVVLLQIAVP TRTDVPEYQK LTSQVHEIVG 420 RINGRFGTLT AVPIHHLDRS LDFHALCALY AVTDVALVTS LRDGMNLVSY EFVACQDAKK 480 GVLILSEFAG AAQSLGAGAI LVNPWNITEV ANSIAQALNM ASEEREKRHK HNFIHVTTHT 540 AQEWAETFVS ELNDTVVEAQ IRTRQVPPPL PNKEAIERYS KASNRLIILG FNATLTEPVD 600 TPERRGDQIK EMELKLHPEL KEPLSALCND PQTTIVVLSG SATEVLDDNF GELDMWLAAE 660 NGMFLRLTKG KWMTTMPEHL NMEWVESVKH VFEYFTERTP RSHLDDRATS LVWNYKYADV 720 DFGRLQARDM LQHLWTGPIS NASVDVVQGS RSVEVRPVGV TKGAAIDRIL GEIVHSKSMT 780 TPIDYVLCIG HFLGKDEDVY TFFEPDLPPE PMGLPRKMTD GQKLPSERRS SLKVPSNKNA 840 SKSAQSKTQR LLLNGEKKNA NHSNGNPRWP SPEKISWNVL DLKRENYYSC TVGRTRTNAR 900 YLLQSSDDVV SFLTELAGAS SASS* 960 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 0 | 1 | 921 | 932 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 93 | 924 | 832 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| pfam00982 | Glyco_transf_20 | 0 | 93 | 554 | 468 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| TIGR02400 | trehalose_OtsA | 0 | 93 | 554 | 464 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
| PRK14501 | PRK14501 | 0 | 93 | 790 | 706 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAA69879.1 | 0 | 1 | 922 | 1 | 941 | trehalose-6-phosphate synthase [Arabidopsis thaliana] |
| RefSeq | NP_177979.1 | 0 | 1 | 922 | 1 | 941 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002285632.1 | 0 | 1 | 922 | 1 | 926 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002331300.1 | 0 | 1 | 921 | 1 | 922 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002531237.1 | 0 | 1 | 923 | 1 | 926 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 88 | 564 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 88 | 564 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 88 | 564 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 88 | 564 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 0 | 88 | 556 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX546763 | 316 | 62 | 377 | 0 |
| DW069910 | 288 | 174 | 461 | 0 |
| CV711307 | 286 | 93 | 378 | 0 |
| ES813375 | 360 | 449 | 808 | 0 |
| CB651133 | 281 | 114 | 394 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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