| Basic Information | |
|---|---|
| Species | Prunus persica |
| Cazyme ID | ppa001057m |
| Family | GT20 |
| Protein Properties | Length: 923 Molecular Weight: 103905 Isoelectric Point: 7.4322 |
| Chromosome | Chromosome/Scaffold: 4 Start: 3498555 End: 3506311 |
| Description | trehalose-6-phosphate synthase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 89 | 552 | 0 |
| KQRLLVVANRLPVSAVRKGEDSWQLEMSVGGLVSVKEFDARWIGWAGVNVPDSVGQKALTKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLFHYLGLP QEDRLATTRSFQSQFDAYKKANQMFADVVHKHYLDGDVVWCHDYHLMFLPKCLKEHNNKMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAADLVGFHTY DYARHFVSACTRILGLEGTPEGVEDQGKLTRVAAFPIGIDSDRFIRALELPQVQEHMKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKFLEENLKWR DKVVLLQIAVPTRTDVPEYQKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFHALCALYAVTDVALVTSLRDGMNLVSYEFVACQASKKGVLILSEFA GAAQSLGAGAILVNPWNVTEVAASIGYALNMPADEREKRHQHNFMHVTTHTSQEWAATFVSELN | |||
| Full Sequence |
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| Protein Sequence Length: 923 Download |
| MARNNYNCNP STPRSRLERL LRERELRRSN RVLHPIEDGN RQAELLGNDN FLTEGENFGL 60 FSEEDFPEGV AAAKAFADGC EWKEGRAPKQ RLLVVANRLP VSAVRKGEDS WQLEMSVGGL 120 VSVKEFDARW IGWAGVNVPD SVGQKALTKA LAEKRCIPVF LDEEIVHQYY NGYCNNILWP 180 LFHYLGLPQE DRLATTRSFQ SQFDAYKKAN QMFADVVHKH YLDGDVVWCH DYHLMFLPKC 240 LKEHNNKMKV GWFLHTPFPS SEIHRTLPSR SELLRSVLAA DLVGFHTYDY ARHFVSACTR 300 ILGLEGTPEG VEDQGKLTRV AAFPIGIDSD RFIRALELPQ VQEHMKELKE RFAGRKVMLG 360 VDRLDMIKGI PQKILAFEKF LEENLKWRDK VVLLQIAVPT RTDVPEYQKL TSQVHEIVGR 420 INGRFGTLTA VPIHHLDRSL DFHALCALYA VTDVALVTSL RDGMNLVSYE FVACQASKKG 480 VLILSEFAGA AQSLGAGAIL VNPWNVTEVA ASIGYALNMP ADEREKRHQH NFMHVTTHTS 540 QEWAATFVSE LNDTIVEAQL RTRQVPPLLP IQVAVDRYLQ SSNRLLILGF NATLTEPKDT 600 LGRRGGQIRE MELKLHPDLK EPLKKLCDDS KTTIVVLSGS DRSVLDDNFG DYNMWLAAEN 660 GMFLRLTMGE WMTTMPENLN MDWVDSVKHV FEYFTERTPR SHFELRETSL VWNYKYADIE 720 FGRIQARDLL QHLWTGPISN ASVDVVQGGR SVEVRAVGVT KGAAIDRILG EIVHNKGMKA 780 PIDYVLCIGH FLPKDEDVYT FFEPELPSEA PPTVPRPTAA NPAMTSVPRI STTKSGSRAA 840 RLKKQRSLST LEKRATVHGI GNAWRPTLTR DKMSLHEGSS VLDLKGDNYF SCAVGRKRSS 900 ARYLLGSSDD IVTLLKALAE GS* 960 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 0 | 1 | 922 | 935 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 82 | 919 | 842 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| pfam00982 | Glyco_transf_20 | 0 | 90 | 553 | 474 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| TIGR02400 | trehalose_OtsA | 0 | 91 | 553 | 469 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
| PRK14501 | PRK14501 | 0 | 91 | 789 | 711 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_177979.1 | 0 | 1 | 920 | 1 | 937 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002305707.1 | 0 | 21 | 921 | 1 | 895 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002331300.1 | 0 | 1 | 922 | 1 | 921 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002522296.1 | 0 | 7 | 922 | 5 | 912 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| RefSeq | XP_002531237.1 | 0 | 1 | 922 | 1 | 923 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 91 | 563 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 91 | 563 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 91 | 563 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 91 | 563 | 3 | 466 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1uqu_B | 0 | 91 | 563 | 3 | 466 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| ES813375 | 361 | 448 | 808 | 0 |
| DW069910 | 288 | 173 | 460 | 0 |
| CX546763 | 304 | 78 | 376 | 0 |
| CV711307 | 293 | 89 | 377 | 0 |
| CX545499 | 310 | 385 | 694 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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