Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa001571m |
Family | GT47 |
Protein Properties | Length: 801 Molecular Weight: 92168.9 Isoelectric Point: 9.4026 |
Chromosome | Chromosome/Scaffold: 7 Start: 21545313 End: 21550707 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 460 | 745 | 0 |
KRFKVWSYKEGELPLVHIGPMTNIYGIEGHFIDEIEREESPFRATHPDRAHTFFLPFSVANIVEYVYLPITQKQDYYRDRLQRIVVDYIGVVARKYPYWN RSHGADHFMASCHDWGPEISVGQPELFKNFIRVLCNANTSEGFQPRRDVPLPEIYVPSRKLGPPYLGQPPNNRPILAFFAGRVHGSIRPILLDNWKDKDD EVQVHEKLPLDQNYTKLMGQSKYCLCPSGFEVASPRVMEAFYAGCVPVLISDNYTLPFSDVLNWSQFSIQIPVAKIPEIKTILQGI |
Full Sequence |
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Protein Sequence Length: 801 Download |
MSYWELPEYM KDNEFILNYY RANWPLPQAL FSVFRWHNET LNVWTHLIGF VLFLGLTMVN 60 LLRVPQVADL LGFFARSTPI SAVTNVSRNF ISGIMTTNLI ELKQMTSQEM EIAAAGHEMG 120 GVAYWPFYVF LGGSMFCLFS SSICHLFSCH SHPLNLLLLR IDYAGITMMI ITSFFPPIYY 180 IFQCDPRWQF IYLGGITIMG VFTIITLLSP KLSSGKFRTF RALLFASMGL FGIVPAVHAS 240 IVNWGNPRRN ATLVYEAAMA FFYLTGTGFY ITRIPERWRP GWFDIAGHSH QIFHVLVVLG 300 ALAHYAAILV MLDWRSTFGF AMTSTAGAFR FPTVAFLLVT LLFLLFFFLS FSPFSGNHLI 360 IPLISSFTAF FNPKESNYTA PPHVSLDGLL TKSMYRRRSG HKNKTSLERI EEDLAQARAA 420 IREAIQSRNY KSERTETFIP RGSIYKNPYA FHQSHIEMRK RFKVWSYKEG ELPLVHIGPM 480 TNIYGIEGHF IDEIEREESP FRATHPDRAH TFFLPFSVAN IVEYVYLPIT QKQDYYRDRL 540 QRIVVDYIGV VARKYPYWNR SHGADHFMAS CHDWGPEISV GQPELFKNFI RVLCNANTSE 600 GFQPRRDVPL PEIYVPSRKL GPPYLGQPPN NRPILAFFAG RVHGSIRPIL LDNWKDKDDE 660 VQVHEKLPLD QNYTKLMGQS KYCLCPSGFE VASPRVMEAF YAGCVPVLIS DNYTLPFSDV 720 LNWSQFSIQI PVAKIPEIKT ILQGIPYEKY LRMQKRVSKV KRHFVLNRPS QPFDVIHMVL 780 HSVWLRRLNS KLDTIHDHNS * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01065 | hlyIII | 1.0e-10 | 112 | 310 | 201 | + channel protein, hemolysin III family. This family includes proteins from pathogenic and non-pathogenic bacteria, Homo sapiens and Drosophila. In Bacillus cereus, a pathogen, it has been show to function as a channel-forming cytolysin. The human protein is expressed preferentially in mature macrophages, consistent with a role cytolytic role. | ||
COG1272 | COG1272 | 7.0e-26 | 10 | 315 | 308 | + Predicted membrane protein, hemolysin III homolog [General function prediction only] | ||
pfam03006 | HlyIII | 1.0e-48 | 34 | 305 | 273 | + Haemolysin-III related. Members of this family are integral membrane proteins. This family includes a protein with hemolytic activity from Bacillus cereus. It has been proposed that YOL002c encodes a Saccharomyces cerevisiae protein that plays a key role in metabolic pathways that regulate lipid and phosphate metabolism. In eukaryotes, members are seven-transmembrane pass molecules found to encode functional receptors with a broad range of apparent ligand specificities, including progestin and adipoQ receptors, and hence have been named PAQR proteins. The mammalian members include progesterone binding proteins. Unlike the case with GPCR receptor proteins, the evolutionary ancestry of the members of this family can be traced back to the Archaea. | ||
pfam03016 | Exostosin | 3.0e-62 | 458 | 745 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
GO:0016021 | integral to membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 389 | 792 | 61 | 465 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 405 | 792 | 235 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 402 | 792 | 10 | 400 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 357 | 789 | 31 | 472 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 402 | 789 | 2 | 391 | PREDICTED: hypothetical protein [Vitis vinifera] |