Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa002395m |
Family | GT47 |
Protein Properties | Length: 679 Molecular Weight: 76862.6 Isoelectric Point: 7.3183 |
Chromosome | Chromosome/Scaffold: 1 Start: 36924872 End: 36927717 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 348 | 629 | 0 |
DTLKVYVYREGERPILHSPFLKGIYASEGWFMKQLEADKKFVTKNPQKAHLYYLPFSSRTLEERLYVPNSHSHKNLIQYLKDYVDMIAVKHPFWNRTGGA DHFLVACHDWAPSETKKYMATCIRALCNSDIKEGFVFGKDVSLPETYIKNDKNPLRDLGGNRPSKRSILAFFAGSMHGYLRPILLQHWEDKDPDMKIFGK LPKVKGNKNYVRYMQSSKYCICAKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVLNWESFAVFVLEKDIPNLKNILLSI |
Full Sequence |
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Protein Sequence Length: 679 Download |
MGQDLLSICQ AETRRLLWIA GMLFAVILVV RHLELPYGNL LSSILSSTKV PLVGKSGFQA 60 GYSPSNSEIV GNLSLSNDLN NTGTYAIHEK ASNTRSSDSV LEGHEGSNRA LEINEDEDDG 120 KDASSGNLVK QNRTIIVENI KPLETNFAQE GGREPEVSSV EKKNTTDNTY LEGRIGNENN 180 TVDVVNSTAG LPVSSPAPPM MNSSPSTAPA IFETNVGAPI KSVDSNVTSV EKDRTTPSEK 240 TENSEQLHSD LNQTEHNSSM TRVPEVKIEP EVPILDVYSI SDMNNLLLQS RASYNSMLAQ 300 WSSPADQELQ YVASQIENAP IIKSDPTLYA LLYRNLSVFK RSYELMEDTL KVYVYREGER 360 PILHSPFLKG IYASEGWFMK QLEADKKFVT KNPQKAHLYY LPFSSRTLEE RLYVPNSHSH 420 KNLIQYLKDY VDMIAVKHPF WNRTGGADHF LVACHDWAPS ETKKYMATCI RALCNSDIKE 480 GFVFGKDVSL PETYIKNDKN PLRDLGGNRP SKRSILAFFA GSMHGYLRPI LLQHWEDKDP 540 DMKIFGKLPK VKGNKNYVRY MQSSKYCICA KGYEVNSPRV VEAIFYECVP VIISDNFVPP 600 FFEVLNWESF AVFVLEKDIP NLKNILLSIP KKKYLQMQMR VKKVQKHFLW HAKPEKYDIF 660 HMILHSIWYN RLHQLKPI* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-71 | 346 | 629 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20855.1 | 0 | 1 | 676 | 1 | 602 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197954.1 | 0 | 8 | 675 | 8 | 652 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002281263.1 | 0 | 1 | 676 | 1 | 667 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002309547.1 | 0 | 201 | 677 | 1 | 470 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002324801.1 | 0 | 283 | 677 | 1 | 397 | predicted protein [Populus trichocarpa] |