Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa002755m |
Family | GT47 |
Protein Properties | Length: 637 Molecular Weight: 72307 Isoelectric Point: 9.0768 |
Chromosome | Chromosome/Scaffold: 7 Start: 20314622 End: 20317275 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 306 | 587 | 0 |
LKVYIYKEGEKPVFHQPLMRGIYASEGWFMKLVEGNKKFVVRDPKKAHLFYLPFDSHMLRLTLSGQNVKNGKKVLEKYLKSYVGLIARKYSFWNRTEGAD HFLVACHDWAPKLTKQCMKNCIRSLCNANVGRDFKIGKDTSLPVTYIRSVENPLQDLGGKPASERSILAFFAGGMHGYLRPILLHYWENKEPDMKIFGPM PHDIESKKIYREYMKSSKYCICARGYEVHTPRVVEAIFYECVPVIISDNYMPPFFEVFNWEAFAVFVQEKDIPNLRDILLSI |
Full Sequence |
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Protein Sequence Length: 637 Download |
MDIAGNIEIR RLLLIIGGVV VIVVASECFE LPSGKKFYFS TADKGSTSTS TVFANVSSSN 60 NSKPSKSNVG VVVGLVANDT DVSDLAPDDD SNSHKELMLE KNLTLDENFP VGTDRNAEDI 120 SVQEKTIDFR NDSLQKTEKT DESYKADNGP KTSSGLTVSE GRNEAGIVPV VSQGISTESP 180 ETLNADSKGN VKQTTETQIE HQKTELWQPV PVTLNGNSTM TSISILKKWN PRPTSLSQMN 240 ALLLRIPVSS PSMSPRRYST RDRELQSAKL EIENAPIIRN NPGLSASVFR NLSKFIRSYD 300 LMDHMLKVYI YKEGEKPVFH QPLMRGIYAS EGWFMKLVEG NKKFVVRDPK KAHLFYLPFD 360 SHMLRLTLSG QNVKNGKKVL EKYLKSYVGL IARKYSFWNR TEGADHFLVA CHDWAPKLTK 420 QCMKNCIRSL CNANVGRDFK IGKDTSLPVT YIRSVENPLQ DLGGKPASER SILAFFAGGM 480 HGYLRPILLH YWENKEPDMK IFGPMPHDIE SKKIYREYMK SSKYCICARG YEVHTPRVVE 540 AIFYECVPVI ISDNYMPPFF EVFNWEAFAV FVQEKDIPNL RDILLSIPEE KYLTMMSSVK 600 MVQQHFFWHK KPVKYDLFHM ILHSVWYNRV LQIKTR* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-59 | 306 | 587 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 6 | 634 | 12 | 711 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 7 | 632 | 722 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CBI28021.1 | 0 | 6 | 636 | 12 | 665 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002280595.1 | 0 | 6 | 636 | 10 | 663 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002281263.1 | 0 | 7 | 636 | 11 | 669 | PREDICTED: hypothetical protein [Vitis vinifera] |