| Basic Information | |
|---|---|
| Species | Prunus persica |
| Cazyme ID | ppa003595m |
| Family | AA3 |
| Protein Properties | Length: 564 Molecular Weight: 61206.9 Isoelectric Point: 5.3935 |
| Chromosome | Chromosome/Scaffold: 1 Start: 6534808 End: 6537068 |
| Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| AA3 | 51 | 546 | 0 |
| EGSYDYVIVGGGTSGCPLAATLSEKYKVLVLERGSLPTAYPNVLTADGFVYNLQQEDDGKTPVERFVSEDGIDNVRGRVLGGTSMINAGVYARANTSIYS ASGVDWDMDLVNQTYEWVEDTIVYKPNAQSWQSVTKTAFLEAGVHPNHGFSLDHEEGTRITGSTFDNKGTRHAADELLNKGNSNNLRVGVHASVEKIIFS NAPGLTATGVIYRDSNGTPHQAFVRGKGEVIVSAGTIGTPQLLLLSGVGPESYLSSLNIPVVLSHPYVGEFLHDNPRNFINILPPNPIEPTIVTVLGISN DFYQCSFSSLPFTTPPFGFFPSTSYPLPNSTFAHFASKVAGPLSYGSLTLKSSSNVRVSPNVKFNYYSNPTDLSHCVSGMKKIGELLSTDALKPYKVEDL PGIEGFNILGIPLPKDQTDDAAFETFCRESVASYWHYHGGCLVGKVLDGDFRVTGINALRVVDGSTFPYTPASHPQGFYLMLGRYVGSKILQERSA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 564 Download |
| MEKSTMSAML LVLHIFVLHL QYSEVHSLAT TSDHDFSYLT FAYDATDLEL EGSYDYVIVG 60 GGTSGCPLAA TLSEKYKVLV LERGSLPTAY PNVLTADGFV YNLQQEDDGK TPVERFVSED 120 GIDNVRGRVL GGTSMINAGV YARANTSIYS ASGVDWDMDL VNQTYEWVED TIVYKPNAQS 180 WQSVTKTAFL EAGVHPNHGF SLDHEEGTRI TGSTFDNKGT RHAADELLNK GNSNNLRVGV 240 HASVEKIIFS NAPGLTATGV IYRDSNGTPH QAFVRGKGEV IVSAGTIGTP QLLLLSGVGP 300 ESYLSSLNIP VVLSHPYVGE FLHDNPRNFI NILPPNPIEP TIVTVLGISN DFYQCSFSSL 360 PFTTPPFGFF PSTSYPLPNS TFAHFASKVA GPLSYGSLTL KSSSNVRVSP NVKFNYYSNP 420 TDLSHCVSGM KKIGELLSTD ALKPYKVEDL PGIEGFNILG IPLPKDQTDD AAFETFCRES 480 VASYWHYHGG CLVGKVLDGD FRVTGINALR VVDGSTFPYT PASHPQGFYL MLGRYVGSKI 540 LQERSASDLK ILDSLKSAAS FVF* |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK02106 | PRK02106 | 7.0e-13 | 392 | 521 | 135 | + choline dehydrogenase; Validated | ||
| PRK02106 | PRK02106 | 1.0e-30 | 53 | 324 | 332 | + choline dehydrogenase; Validated | ||
| TIGR01810 | betA | 9.0e-38 | 55 | 541 | 560 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
| COG2303 | BetA | 2.0e-47 | 49 | 547 | 561 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
| PLN02785 | PLN02785 | 5.0e-151 | 37 | 544 | 548 | + Protein HOTHEAD | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1JU2 | 0 | 28 | 563 | 1 | 536 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3GDN | 0 | 28 | 548 | 1 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
| GenBank | AAL11514.1 | 0 | 1 | 563 | 1 | 563 | AF412329_1 R-oxynitrile lyase isoenzyme 1 precursor [Prunus dulcis] |
| Swiss-Prot | P52706 | 0 | 1 | 563 | 1 | 563 | MDL1_PRUSE RecName: Full=(R)-mandelonitrile lyase 1; AltName: Full=Hydroxynitrile lyase 1; Short=(R)-oxynitrilase 1; Flags: Precursor |
| Swiss-Prot | P52707 | 0 | 1 | 563 | 1 | 573 | MDL3_PRUSE RecName: Full=(R)-mandelonitrile lyase 3; AltName: Full=Hydroxynitrile lyase 3; Short=(R)-oxynitrilase 3; Flags: Precursor |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ju2_B | 0 | 28 | 563 | 1 | 536 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 1ju2_A | 0 | 28 | 563 | 1 | 536 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_B | 0 | 28 | 548 | 1 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdp_A | 0 | 28 | 548 | 1 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
| PDB | 3gdn_B | 0 | 28 | 548 | 1 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
