Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa004308m |
Family | AA3 |
Protein Properties | Length: 518 Molecular Weight: 56687.8 Isoelectric Point: 7.8278 |
Chromosome | Chromosome/Scaffold: 1 Start: 27148062 End: 27149782 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 36 | 507 | 0 |
LSGKSFDYIVVGGGTAGCPLAATLSEKFSVLLVERGSSPYGNPLVLETKNYGLSLLQTDKYTSVAQSFISNDGVPNLRGRVLGGSSAINGGFYSRASEDF VQKVGWDKEAVMGAYQWVESRIVFKPELTPWQYVAEFSFLEAGIFPYNGFSLEHIEGTKVGGSVFDEWGRRHTSADLLEAGNPNNITVLLNATVKNVIFR EKGNRNETIARGIRFIKSDGNSSQTYDAYLNQPENSCSWGDVILAAGALGSPQILLLSGIGPQKHIKKFNIQLAADLKGVGKGMKDNPGIALLADSKPKN FPPEPPKVVGIADHFKIIIEAGILPISLNATVMPIAAKLAFPESEGKLELNSTDPRENPSVTFNYLAKEKDWARCVKLGQLLERVVRSESIAFFLGLERK NELMSTEDELRKLCKKNVRTFYHYHGGCSVGSVVDKDYRVYGVKGLRVVDGSTFLESPGTNPMATLLMLGRY |
Full Sequence |
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Protein Sequence Length: 518 Download |
MGFSFYLLLL FVDLALCSSW LQGRTLPHMT SDVNDLSGKS FDYIVVGGGT AGCPLAATLS 60 EKFSVLLVER GSSPYGNPLV LETKNYGLSL LQTDKYTSVA QSFISNDGVP NLRGRVLGGS 120 SAINGGFYSR ASEDFVQKVG WDKEAVMGAY QWVESRIVFK PELTPWQYVA EFSFLEAGIF 180 PYNGFSLEHI EGTKVGGSVF DEWGRRHTSA DLLEAGNPNN ITVLLNATVK NVIFREKGNR 240 NETIARGIRF IKSDGNSSQT YDAYLNQPEN SCSWGDVILA AGALGSPQIL LLSGIGPQKH 300 IKKFNIQLAA DLKGVGKGMK DNPGIALLAD SKPKNFPPEP PKVVGIADHF KIIIEAGILP 360 ISLNATVMPI AAKLAFPESE GKLELNSTDP RENPSVTFNY LAKEKDWARC VKLGQLLERV 420 VRSESIAFFL GLERKNELMS TEDELRKLCK KNVRTFYHYH GGCSVGSVVD KDYRVYGVKG 480 LRVVDGSTFL ESPGTNPMAT LLMLGRYQGI KILEDRN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 7.0e-32 | 377 | 505 | 136 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR03970 | Rv0697 | 1.0e-38 | 42 | 505 | 515 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
TIGR01810 | betA | 4.0e-46 | 42 | 505 | 548 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
COG2303 | BetA | 6.0e-49 | 37 | 516 | 559 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 8.0e-169 | 40 | 516 | 540 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_563939.1 | 0 | 5 | 516 | 7 | 503 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
RefSeq | XP_002312249.1 | 0 | 29 | 517 | 1 | 488 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002315047.1 | 0 | 23 | 515 | 1 | 489 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002315048.1 | 0 | 7 | 516 | 16 | 526 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002522448.1 | 0 | 7 | 516 | 16 | 525 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 32 | 517 | 17 | 518 | A Chain A, Crystal Structure Of The Polygalacturonase From Colletotrichum Lupini And Its Implications For The Interaction With Polygalacturonase- Inhibiting Proteins |
PDB | 3gdp_A | 0 | 32 | 517 | 17 | 518 | A Chain A, Crystal Structure Of The Polygalacturonase From Colletotrichum Lupini And Its Implications For The Interaction With Polygalacturonase- Inhibiting Proteins |
PDB | 3gdn_B | 0 | 32 | 517 | 17 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 32 | 517 | 17 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 32 | 517 | 17 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |