Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa004491m |
Family | GT47 |
Protein Properties | Length: 508 Molecular Weight: 58186.5 Isoelectric Point: 9.3631 |
Chromosome | Chromosome/Scaffold: 7 Start: 2249696 End: 2253253 |
Description | exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 116 | 431 | 0 |
ALKVFMYDLPHEFHFGLLDWKPQGRSVWPDLQTKVPAYPGGLNLQHSIEYWLTLDILASELPNPPNVRTAIRVQNSSEADIIFIPFFSSLSYNRFSKINP HQKKSNNRLLQDKLVKYVTAQQEWKISGGRDHLIVAHHPNSLLDGRMKLWPATFILSDFGRYPPNIANVEKDIIAPYKHVIKSYVNDSSTFDSRPTLLYF QGAIYRKDGGFVRQELFYLLQDEKDVHFTFGSVQKDGIKKASQGMHTSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDDIELPYEDVLDYSEFCIFVRT RDALKKNFLVNLTRSI |
Full Sequence |
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Protein Sequence Length: 508 Download |
MAERHASSLA VNTRKSLFCL FILTSTLFIL SWFFVLRSTG SPHFIDHKLL PNSKLLAMID 60 NGISGSESQN DVEPSVGNRS ILVDKEEEEK PTISSQDKEA SQANNDVKCN TNGKLALKVF 120 MYDLPHEFHF GLLDWKPQGR SVWPDLQTKV PAYPGGLNLQ HSIEYWLTLD ILASELPNPP 180 NVRTAIRVQN SSEADIIFIP FFSSLSYNRF SKINPHQKKS NNRLLQDKLV KYVTAQQEWK 240 ISGGRDHLIV AHHPNSLLDG RMKLWPATFI LSDFGRYPPN IANVEKDIIA PYKHVIKSYV 300 NDSSTFDSRP TLLYFQGAIY RKDGGFVRQE LFYLLQDEKD VHFTFGSVQK DGIKKASQGM 360 HTSKFCLNIA GDTPSSNRLF DAIASHCVPV IISDDIELPY EDVLDYSEFC IFVRTRDALK 420 KNFLVNLTRS IGMDEWTQMW RRLQEVQKFY EFQYPSKEGD AVQMIWQAVA RKVPAIRMKL 480 NKSRRFSRSY VRKEKGLSRI PSPSNFW* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-54 | 117 | 431 | 325 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33321.1 | 0 | 1 | 507 | 1 | 509 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
EMBL | CAN68950.1 | 0 | 1 | 507 | 1 | 488 | hypothetical protein [Vitis vinifera] |
RefSeq | XP_002268382.1 | 0 | 1 | 507 | 1 | 488 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002319201.1 | 0 | 1 | 487 | 3 | 450 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002530948.1 | 0 | 1 | 504 | 1 | 497 | catalytic, putative [Ricinus communis] |