y
Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa004627m |
Family | GT47 |
Protein Properties | Length: 500 Molecular Weight: 56792.7 Isoelectric Point: 10.0004 |
Chromosome | Chromosome/Scaffold: 5 Start: 15787571 End: 15789781 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 116 | 434 | 0 |
LLRVFMYELPPEFHFGLLGWKGKENQTWPNVSISSRIPPYPGGLNLQHSIEYWLTLDLLASNIPTVVRPCTVVRVHNSSEADVIFVPFFSSLSYNRHSKL HGKEKVSVNKMLQNKLVQFLKGRDEWKRKGGKDHLIVAHHPNSMLDARRKLGSAMFVLADFGRYPAEIANLEKDVIAPYRHVVLTVDSSKSASFEERPIL LYFRGAIYRKDGGVIRQELYYILKDEKDVHFSFGSVQGNGINKASQGMASSKFCLNIAGDTPSSNRLFDAIASHCVPVIISDEIELPFEEVLDYSEFCIF VHASDAVKKGYLLNLLQGI |
Full Sequence |
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Protein Sequence Length: 500 Download |
MPEKSRLPSK FLFYLITVSV FLLILSSVFL LQFSKTSFTP SSVFKLILVN GTSVYFEPLV 60 KSRQKQLPFL SSEVSRVDAI RSSKRSELAC QVSNSSKKLG SLRKMKTMAC DSTQALLRVF 120 MYELPPEFHF GLLGWKGKEN QTWPNVSISS RIPPYPGGLN LQHSIEYWLT LDLLASNIPT 180 VVRPCTVVRV HNSSEADVIF VPFFSSLSYN RHSKLHGKEK VSVNKMLQNK LVQFLKGRDE 240 WKRKGGKDHL IVAHHPNSML DARRKLGSAM FVLADFGRYP AEIANLEKDV IAPYRHVVLT 300 VDSSKSASFE ERPILLYFRG AIYRKDGGVI RQELYYILKD EKDVHFSFGS VQGNGINKAS 360 QGMASSKFCL NIAGDTPSSN RLFDAIASHC VPVIISDEIE LPFEEVLDYS EFCIFVHASD 420 AVKKGYLLNL LQGIKQDKWT KMWERLKEIV HQFEYQYPSQ PGDAVDMIWQ AVSHKISSIQ 480 LKFHRKKRYD RSTSGIITK* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-54 | 117 | 434 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD55303.1 | 0 | 1 | 492 | 1 | 449 | AC008263_34 F25A4.34 [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 1 | 492 | 1 | 448 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 87 | 492 | 4 | 409 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 117 | 491 | 3 | 374 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 1 | 491 | 1 | 486 | catalytic, putative [Ricinus communis] |