Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa004757m |
Family | GT47 |
Protein Properties | Length: 494 Molecular Weight: 57033.5 Isoelectric Point: 9.2293 |
Chromosome | Chromosome/Scaffold: 6 Start: 28520161 End: 28522384 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 160 | 442 | 0 |
KRFKIWAYREGELPMVHNGPTTYIYSIEGQFIFEMESGPSRFMAEHPDEAHAFFLPLSVSKITDFLIRPHHETFFHRLHRVFTDYIYVISDKYPYWNRSA GGDHFFVSCHDWAPIISRDDPRPYKNLMKVLCNANTSEGFKPTRDVSLPEYNLKAYELGPPRFGERPSQRPILAFFAGAAHGDIRSILFEHWKEKDDEVR VYEKLPEKMNYHKLMGQTKFCLCPSGSEVASPRVVEAMYAGCVPVLISDYYAVPFDDVLDWTKFSIQIPPKRIPDIKSILKAV |
Full Sequence |
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Protein Sequence Length: 494 Download |
MAEPPLDFRS PCLVSVTLIL LLLVALLFSP LNQQHHLSLN LSSSLTSPSS SFYHQQQITT 60 DNHTTLHFAP APSPSQALLE FQRHQSPPST SAPQLTHTTI KKNQSKTERI EQELSVARAI 120 IRKAIVTKNC TSNSNEIYIP TGSVYRNPYA FHQSHVEMVK RFKIWAYREG ELPMVHNGPT 180 TYIYSIEGQF IFEMESGPSR FMAEHPDEAH AFFLPLSVSK ITDFLIRPHH ETFFHRLHRV 240 FTDYIYVISD KYPYWNRSAG GDHFFVSCHD WAPIISRDDP RPYKNLMKVL CNANTSEGFK 300 PTRDVSLPEY NLKAYELGPP RFGERPSQRP ILAFFAGAAH GDIRSILFEH WKEKDDEVRV 360 YEKLPEKMNY HKLMGQTKFC LCPSGSEVAS PRVVEAMYAG CVPVLISDYY AVPFDDVLDW 420 TKFSIQIPPK RIPDIKSILK AVPYSKYLKL QKRVMQVRRH FELNRPAKPY DVFHMVLHSV 480 WLRRLNIRLP DRF* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-58 | 158 | 442 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI25529.1 | 0 | 105 | 489 | 2 | 386 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 94 | 490 | 72 | 476 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 102 | 490 | 2 | 395 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002266490.1 | 0 | 105 | 490 | 2 | 386 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002515488.1 | 0 | 12 | 489 | 17 | 468 | catalytic, putative [Ricinus communis] |