Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa004838m |
Family | GT47 |
Protein Properties | Length: 490 Molecular Weight: 55137.2 Isoelectric Point: 8.6485 |
Chromosome | Chromosome/Scaffold: 6 Start: 17582672 End: 17584223 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 102 | 428 | 0 |
VAVYVYPLPPKFNTGLLSRCKTLNVYTDMCPHVANRGLGQPLPKLGSPAAWFATHQFIAEMIFHARVENHPCRTLDPARAALFYVPFYGGLHASSMFKEA NLTSRDELAVDLVHHLQAQPWWGRNSGRDHFIALGRTAWDFMRATDGPDFGANSLLNLPAVKNMSVLTVERHPWQGSNQHGIPYPSYFHPSTWQEILTWQ NKVREMNRPNLFSFIGGPRKGLEKAAIRNEFIRQCGESTRCFLMNCGPSGASKCHEPSEVLKVMTESTFCLQAPGDSFTRRSTFDSVLAGCIPVFFSPHT AYTQYKWFLPEEVKTYSVYIDEKSPAS |
Full Sequence |
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Protein Sequence Length: 490 Download |
MFSRKQISPL NTPLEEEKDK YYYSKYNETQ FSLNNPNLKF AALVFIFLSS WLLLLLFWFP 60 PKTTNNVAVL HLAHKTQNAE TINLATAATK SPFKVPTCDP SVAVYVYPLP PKFNTGLLSR 120 CKTLNVYTDM CPHVANRGLG QPLPKLGSPA AWFATHQFIA EMIFHARVEN HPCRTLDPAR 180 AALFYVPFYG GLHASSMFKE ANLTSRDELA VDLVHHLQAQ PWWGRNSGRD HFIALGRTAW 240 DFMRATDGPD FGANSLLNLP AVKNMSVLTV ERHPWQGSNQ HGIPYPSYFH PSTWQEILTW 300 QNKVREMNRP NLFSFIGGPR KGLEKAAIRN EFIRQCGEST RCFLMNCGPS GASKCHEPSE 360 VLKVMTESTF CLQAPGDSFT RRSTFDSVLA GCIPVFFSPH TAYTQYKWFL PEEVKTYSVY 420 IDEKSPASRK IEDELLKISG EKVKAMREKL VDLIPSLTYA HPNATDVGFG DAVDVTLASL 480 ANHVSKMMN* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-66 | 104 | 428 | 336 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 2 | 481 | 3 | 444 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 2 | 481 | 3 | 444 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 96 | 488 | 117 | 503 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 98 | 480 | 1 | 391 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 80 | 480 | 4 | 412 | predicted protein [Populus trichocarpa] |