| Basic Information | |
|---|---|
| Species | Prunus persica |
| Cazyme ID | ppa005428m |
| Family | GT47 |
| Protein Properties | Length: 463 Molecular Weight: 52807.6 Isoelectric Point: 9.6111 |
| Chromosome | Chromosome/Scaffold: 8 Start: 1655101 End: 1661806 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 88 | 385 | 0 |
| DLKIYVYDDREIDGLKALMRGRDGTIDSSTCLKGQWGTQVKIHRLLLKSRFRTQKKGEADLFFVPAYTKCVRMMGGLNDKEINQTYVKVLSQMPYFRRSG GRDHIFVFPSGAGAHLFRSWVTYINRSIILTPEGDRTDKKDTSAFNTWKDIIIPGNVEDGMTTNGATLVHPLPLSKRKFLANYLGRAQGKVGRLKLIELS KQFPDKLECPELKFSGPDKLGRIDYFEHLHNAKFCLAPRGESSWTLRFYEAFFVECVPVILSDQVELPFQNVVDYTQISIKWPSTRIGPELLQYLESI | |||
| Full Sequence |
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| Protein Sequence Length: 463 Download |
| MGSINNKARP FGGQHHHQQP LCTRTHQIGA LLLVAATFFF TSLFDRSFRP CASHFSTVDL 60 IPTSRSSVHV SDGRDLLWPH RGYGPHLDLK IYVYDDREID GLKALMRGRD GTIDSSTCLK 120 GQWGTQVKIH RLLLKSRFRT QKKGEADLFF VPAYTKCVRM MGGLNDKEIN QTYVKVLSQM 180 PYFRRSGGRD HIFVFPSGAG AHLFRSWVTY INRSIILTPE GDRTDKKDTS AFNTWKDIII 240 PGNVEDGMTT NGATLVHPLP LSKRKFLANY LGRAQGKVGR LKLIELSKQF PDKLECPELK 300 FSGPDKLGRI DYFEHLHNAK FCLAPRGESS WTLRFYEAFF VECVPVILSD QVELPFQNVV 360 DYTQISIKWP STRIGPELLQ YLESIPDENI EGMISRGRQV RCLWAYASES ASCSAMHAIL 420 WELQRKVRLF HQSTETFWLH NGSVVNRNLV QFSDWRPPMP LP* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 9.0e-45 | 89 | 385 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564141.1 | 0 | 1 | 462 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002265632.1 | 0 | 1 | 462 | 1 | 459 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002300942.1 | 0 | 1 | 462 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002307477.1 | 0 | 1 | 462 | 1 | 460 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002526175.1 | 0 | 22 | 462 | 21 | 453 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CX668832 | 291 | 149 | 439 | 0 |
| FE707914 | 279 | 129 | 407 | 0 |
| FE707913 | 274 | 190 | 463 | 0 |
| BX841155 | 331 | 5 | 335 | 0 |
| EH692645 | 270 | 166 | 435 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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