Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa017740m |
Family | GT47 |
Protein Properties | Length: 393 Molecular Weight: 45476.4 Isoelectric Point: 9.3084 |
Chromosome | Chromosome/Scaffold: 7 Start: 21542368 End: 21543803 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 58 | 343 | 0 |
KRFKVWSYKEGEQPLVHFGPVNNIYGIEGQFIDEIEREESPFRATHPDEAHTFFLPVSVANIVHYVYMPITRKQDYYRDRLQRVVMDYIGVVANKYPYWN RSNGADHFMASCHDWAPEVSVGKPELFTNFIRVLCNANTSEGFQPKRDVSLPEIYLPYGRLGPPSLGQAPNNRPILAFFAGRVHGPIRPMLLDYWKGKDD EVQVHEKLPKGLNYTKLMGQSKYCLCPSGFEVASPRVVEAFYAGCVPVLISDNYTLPFSDVLNWSQFSVQIPVARIPEIKTILQSI |
Full Sequence |
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Protein Sequence Length: 393 Download |
GRTSLEKIEE DLAKARAAIL EAIRFKKYTS EKTETFVPRG TIYKNPYAFH QSHIEMVKRF 60 KVWSYKEGEQ PLVHFGPVNN IYGIEGQFID EIEREESPFR ATHPDEAHTF FLPVSVANIV 120 HYVYMPITRK QDYYRDRLQR VVMDYIGVVA NKYPYWNRSN GADHFMASCH DWAPEVSVGK 180 PELFTNFIRV LCNANTSEGF QPKRDVSLPE IYLPYGRLGP PSLGQAPNNR PILAFFAGRV 240 HGPIRPMLLD YWKGKDDEVQ VHEKLPKGLN YTKLMGQSKY CLCPSGFEVA SPRVVEAFYA 300 GCVPVLISDN YTLPFSDVLN WSQFSVQIPV ARIPEIKTIL QSIPYEKYLK MQKRVSRVHR 360 HFVLNRPSKP FDVIHMVLHS VWLRRLDYKL ET* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-64 | 56 | 343 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | ABP03872.1 | 0 | 3 | 390 | 77 | 465 | Exostosin-like [Medicago truncatula] |
GenBank | ABP03873.1 | 0 | 3 | 390 | 235 | 613 | Exostosin-like [Medicago truncatula] |
EMBL | CBI21065.1 | 0 | 2 | 390 | 12 | 400 | unnamed protein product [Vitis vinifera] |
EMBL | CBI25537.1 | 0 | 2 | 390 | 85 | 475 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002263848.1 | 0 | 2 | 390 | 4 | 394 | PREDICTED: hypothetical protein [Vitis vinifera] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
EC939466 | 292 | 2 | 291 | 0 |
JK524792 | 252 | 40 | 291 | 0 |
CO983212 | 231 | 161 | 390 | 0 |
GO373511 | 255 | 136 | 390 | 0 |
GO363500 | 280 | 86 | 364 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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