Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa017934m |
Family | GT47 |
Protein Properties | Length: 358 Molecular Weight: 40515.4 Isoelectric Point: 10.2809 |
Chromosome | Chromosome/Scaffold: 6 Start: 17587886 End: 17589076 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 12 | 272 | 1.1e-37 |
KNMSVYVYPLPAKFNLGLLRHCHNLNVHTDMCPHVANSGLGQTISSGGWFAHQPVHRGDDLPRTRAASPNKFRERNLTARDELDVSLVDFIQAQPWWNRR NGKDHFMALGRVVQDFIRKPNDRDYGAGRLLNLPAVKNMSVLIIERHPWQGKNQYGIPYPSYFHPSTRQEMAWWQNKMRKVRRPYLFSFIGAPRRKAAIR NEFIRQCGESTRCKLLNCGTPDGRSKCGEPSEVLKVMTESRFCLQAPGDSFTRRSTFDSVL |
Full Sequence |
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Protein Sequence Length: 358 Download |
NKSPSAATTC DKNMSVYVYP LPAKFNLGLL RHCHNLNVHT DMCPHVANSG LGQTISSGGW 60 FAHQPVHRGD DLPRTRAASP NKFRERNLTA RDELDVSLVD FIQAQPWWNR RNGKDHFMAL 120 GRVVQDFIRK PNDRDYGAGR LLNLPAVKNM SVLIIERHPW QGKNQYGIPY PSYFHPSTRQ 180 EMAWWQNKMR KVRRPYLFSF IGAPRRKAAI RNEFIRQCGE STRCKLLNCG TPDGRSKCGE 240 PSEVLKVMTE SRFCLQAPGD SFTRRSTFDS VLGYGWYLPG ERSSYSVFID QKSKASERIE 300 EELMKISSKK VKMMREKLLG LVPSLTYAHP NATNSGIGDA VDVALVSLAK QVNKIIN* 360 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-40 | 12 | 306 | 333 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAC42883.1 | 0 | 3 | 351 | 60 | 446 | unknown protein [Arabidopsis thaliana] |
RefSeq | NP_177014.1 | 0 | 3 | 351 | 60 | 446 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002270383.1 | 0 | 16 | 352 | 125 | 499 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002300452.1 | 0 | 10 | 348 | 1 | 391 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002336132.1 | 0 | 5 | 348 | 17 | 412 | predicted protein [Populus trichocarpa] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
DY265125 | 318 | 17 | 286 | 0 |
FC899396 | 311 | 17 | 279 | 0 |
DY277080 | 293 | 14 | 273 | 0 |
DR929877 | 274 | 105 | 352 | 0 |
DY298787 | 325 | 44 | 317 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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