Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa020579m |
Family | AA3 |
Protein Properties | Length: 547 Molecular Weight: 60234.5 Isoelectric Point: 9.7023 |
Chromosome | Chromosome/Scaffold: 1 Start: 639233 End: 641217 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 50 | 535 | 0 |
LEGSYDYIVVGGGTSGCPLAATLSANYKVLLLERGSLPIDYPNTSTSSGFAANLQQEDDGKTPVERFVSLDGIDNVRGRVLGGTSTISAGTYARANASFY SESGVNWDLNLVNKAYQWVEDSLVVRPKSQSWQSVIGKAYLEAGFLPDNGFSLDHKEGTRLTGSIFDNNGTRHASDELLSKGNPKNLRVAVHASVEKILF SSNKSSLSAIGVIYRDSYGRPHRAFVLGKGEVILSAGTIGTAHLLLLSGVGPKSQLLSQRIPVVRHHPHVGQFVYDNPRNFINILPPYPIEASIVTVIGV RSEYYQISLSSLPLEKPAYSLFPASYPLPNSTFAHIVSQVPGPLSYGSVTLKSSFNVKIPPNVRFNYFSNPTDLALCVKGMKKLGEVLRTKTLRPYKARN VPGIEGFNYLGAPLPKNQNDDKAFQRFCRDNFATYWHYHGGSLVGKVLDDRFRVTGIKALRVVDASTFPYEPNSHPMGFYMMLGRY |
Full Sequence |
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Protein Sequence Length: 547 Download |
MEKSTMSAIL LALHLLFVHL QYSGVHSLAN SHPHDFRYLK YVYNATDRRL EGSYDYIVVG 60 GGTSGCPLAA TLSANYKVLL LERGSLPIDY PNTSTSSGFA ANLQQEDDGK TPVERFVSLD 120 GIDNVRGRVL GGTSTISAGT YARANASFYS ESGVNWDLNL VNKAYQWVED SLVVRPKSQS 180 WQSVIGKAYL EAGFLPDNGF SLDHKEGTRL TGSIFDNNGT RHASDELLSK GNPKNLRVAV 240 HASVEKILFS SNKSSLSAIG VIYRDSYGRP HRAFVLGKGE VILSAGTIGT AHLLLLSGVG 300 PKSQLLSQRI PVVRHHPHVG QFVYDNPRNF INILPPYPIE ASIVTVIGVR SEYYQISLSS 360 LPLEKPAYSL FPASYPLPNS TFAHIVSQVP GPLSYGSVTL KSSFNVKIPP NVRFNYFSNP 420 TDLALCVKGM KKLGEVLRTK TLRPYKARNV PGIEGFNYLG APLPKNQNDD KAFQRFCRDN 480 FATYWHYHGG SLVGKVLDDR FRVTGIKALR VVDASTFPYE PNSHPMGFYM MLGRYVGLQI 540 QRENSV* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK02106 | PRK02106 | 1.0e-23 | 53 | 321 | 318 | + choline dehydrogenase; Validated | ||
TIGR01810 | betA | 7.0e-27 | 55 | 533 | 544 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
TIGR03970 | Rv0697 | 2.0e-32 | 55 | 533 | 517 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
COG2303 | BetA | 6.0e-41 | 47 | 544 | 561 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 2.0e-144 | 53 | 543 | 533 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC61982.1 | 0 | 1 | 546 | 1 | 547 | (R)-(+)-mandelonitrile lyase isoform MDL5 precursor [Prunus serotina] |
GenBank | AAL11514.1 | 0 | 1 | 545 | 1 | 545 | AF412329_1 R-oxynitrile lyase isoenzyme 1 precursor [Prunus dulcis] |
GenBank | AAP84580.1 | 0 | 1 | 546 | 1 | 547 | hnl isoenzyme 5 [Prunus dulcis] |
Swiss-Prot | O24243 | 0 | 1 | 546 | 1 | 547 | MDL1_PRUDU RecName: Full=(R)-mandelonitrile lyase 1; AltName: Full=Hydroxynitrile lyase 1; Short=(R)-oxynitrilase 1; Flags: Precursor |
Swiss-Prot | P52707 | 0 | 1 | 545 | 1 | 546 | MDL3_PRUSE RecName: Full=(R)-mandelonitrile lyase 3; AltName: Full=Hydroxynitrile lyase 3; Short=(R)-oxynitrilase 3; Flags: Precursor |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1ju2_B | 0 | 28 | 545 | 1 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 1ju2_A | 0 | 28 | 545 | 1 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_B | 0 | 28 | 545 | 1 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdp_A | 0 | 28 | 545 | 1 | 518 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |
PDB | 3gdn_B | 0 | 28 | 545 | 1 | 518 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |