Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa023392m |
Family | GT47 |
Protein Properties | Length: 460 Molecular Weight: 53049.1 Isoelectric Point: 9.4225 |
Chromosome | Chromosome/Scaffold: 1 Start: 39306687 End: 39310455 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 125 | 411 | 0 |
EKKFKVYVYTEGDPPMAHDGPCKDIYSIEGRFIHEMENGAVGRRFKTKSPKRAHVYFMPFSVTWMVKYLYKPFTYNLTPLRDFVADYVRVISSRHPFWNR TRGADHFMLGCHDWTPHASAGNQFLYNTSIRVLCNANTSEGFNPQKDVSLPEIYLYGGNVPSKLISPPPPQTPRPYLGFFAGGLHGPIRPILLAHWKTRD EDLRVYEYLPEGEDYASMMLKSRFCLCPSGHEVASPRIVEAIYAECVPVILSEHYALPFSDVLRWEAFSIRVEVSEIWRLKEVLMAV |
Full Sequence |
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Protein Sequence Length: 460 Download |
SRSFHVQYSL VSVLLSLCIA SIIAVSMICG HHFDRSVRIS GAELYQYGPV SIPLVELRSK 60 RKIPKPKASR EQELEQGLAR ARASIRRAVW SPNRSSTFDD DVSFPGGSVV YRNPGAFYQS 120 YLEMEKKFKV YVYTEGDPPM AHDGPCKDIY SIEGRFIHEM ENGAVGRRFK TKSPKRAHVY 180 FMPFSVTWMV KYLYKPFTYN LTPLRDFVAD YVRVISSRHP FWNRTRGADH FMLGCHDWTP 240 HASAGNQFLY NTSIRVLCNA NTSEGFNPQK DVSLPEIYLY GGNVPSKLIS PPPPQTPRPY 300 LGFFAGGLHG PIRPILLAHW KTRDEDLRVY EYLPEGEDYA SMMLKSRFCL CPSGHEVASP 360 RIVEAIYAEC VPVILSEHYA LPFSDVLRWE AFSIRVEVSE IWRLKEVLMA VPEEKYRWLV 420 ENLRVVRRHF ELNQPAKRFD VFHMILHSVW LRRINLRFA* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 4.0e-59 | 124 | 411 | 307 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI21064.1 | 0 | 9 | 459 | 7 | 478 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197913.4 | 0 | 50 | 459 | 74 | 480 | catalytic [Arabidopsis thaliana] |
RefSeq | XP_002285237.1 | 0 | 124 | 459 | 1 | 334 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002324871.1 | 0 | 124 | 459 | 1 | 334 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002515489.1 | 0 | 7 | 459 | 7 | 481 | catalytic, putative [Ricinus communis] |