| Basic Information | |
|---|---|
| Species | Prunus persica |
| Cazyme ID | ppa023537m |
| Family | GH29 |
| Protein Properties | Length: 430 Molecular Weight: 48333.3 Isoelectric Point: 7.4527 |
| Chromosome | Chromosome/Scaffold: 2 Start: 24618846 End: 24620556 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 3 | 270 | 0 |
| NPAIFNPVGLNANQWLSTAADAGISLVILTAKHHDGFCLWPSKYTDHSVEKSPWKNGHGDVVQELVNAAKPLGVDVGLYLSPWDRHDQRYGHEIAYNQYY LAQLQELLNRYGSVREIWFDGSKGKNAPNMSYYFTDWFSMVKELQSSINIFSDAGPDVRWVGNEKGFAGSTCWSTINRTSLSIGNASIEDYLNNGDPKGT DWLPAECDVSIRQGWFWHKSQTPKSLSRLLEIYYNSVGRNCVLLLNVPPNSTGLISEVDVQRLREFRR | |||
| Full Sequence |
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| Protein Sequence Length: 430 Download |
| HENPAIFNPV GLNANQWLST AADAGISLVI LTAKHHDGFC LWPSKYTDHS VEKSPWKNGH 60 GDVVQELVNA AKPLGVDVGL YLSPWDRHDQ RYGHEIAYNQ YYLAQLQELL NRYGSVREIW 120 FDGSKGKNAP NMSYYFTDWF SMVKELQSSI NIFSDAGPDV RWVGNEKGFA GSTCWSTINR 180 TSLSIGNASI EDYLNNGDPK GTDWLPAECD VSIRQGWFWH KSQTPKSLSR LLEIYYNSVG 240 RNCVLLLNVP PNSTGLISEV DVQRLREFRR AIDTIFSTNL AEKCSVKVSS QRGGKGGGFG 300 PENVLDSDHL WTYWAPRDDD KEGHWIEIRG TGTDGGLRFN VIRIQEAIGL GQRIKRHDIY 360 VDGKRVANGT TVGYKRLHRL EEGVIHGKIV KIRIEESKGL PLISSIGLHF DPFWHPNPNG 420 ERPQEKGMK* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 8.0e-29 | 7 | 268 | 278 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 1.0e-30 | 7 | 268 | 280 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 2.0e-46 | 2 | 408 | 422 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| GO:0007155 | cell adhesion |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 1 | 420 | 51 | 465 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 1 | 417 | 48 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 1 | 417 | 69 | 483 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 1 | 417 | 70 | 484 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 1 | 416 | 71 | 483 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 5 | 409 | 47 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 5 | 409 | 47 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3mo4_B | 0 | 1 | 404 | 53 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3mo4_A | 0 | 1 | 404 | 53 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
| PDB | 3ues_B | 0 | 1 | 404 | 51 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CX044171 | 296 | 65 | 358 | 0 |
| EY198039 | 318 | 97 | 414 | 0 |
| HE642643 | 266 | 1 | 264 | 0 |
| EX687577 | 271 | 147 | 417 | 0 |
| DR921868 | 300 | 117 | 416 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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