Basic Information | |
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Species | Prunus persica |
Cazyme ID | ppa024657m |
Family | GT47 |
Protein Properties | Length: 409 Molecular Weight: 46683.2 Isoelectric Point: 9.1572 |
Chromosome | Chromosome/Scaffold: 1 Start: 21385327 End: 21386692 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 75 | 359 | 0 |
SFKIYVYPTNSASSSFASSASIFLPHPNPFDPKLGNYFSEHMFKLSLLSSSLITTNPEKANLFFLPFSVNLLRNDPRVHSEPSIADFVARYTTSISQDLP FWNASLGSDHFYACCHSVCREASSKHVGLRNNAIQLTCSSSYFQRFYVTHKDVALPQVWPRPPQHALNPPHARDKLVYFAGRIQNSNIRQQLVDLWGNET YMDIFPGQPSYPYEEGFRRSKYCLHVKGYEVNTARVSDAVHYGCVPVIISNHYELPFANVLDWSKFSVIVNNGDVALLKRTLLSI |
Full Sequence |
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Protein Sequence Length: 409 Download |
MPKLKRRLLL TVLLLLAVSS ASWFAIFLLH SSEEQGSPSN LGRLSASPPT PLPVDSGPYH 60 NWQLFAADFE DMIQSFKIYV YPTNSASSSF ASSASIFLPH PNPFDPKLGN YFSEHMFKLS 120 LLSSSLITTN PEKANLFFLP FSVNLLRNDP RVHSEPSIAD FVARYTTSIS QDLPFWNASL 180 GSDHFYACCH SVCREASSKH VGLRNNAIQL TCSSSYFQRF YVTHKDVALP QVWPRPPQHA 240 LNPPHARDKL VYFAGRIQNS NIRQQLVDLW GNETYMDIFP GQPSYPYEEG FRRSKYCLHV 300 KGYEVNTARV SDAVHYGCVP VIISNHYELP FANVLDWSKF SVIVNNGDVA LLKRTLLSIT 360 RRKYMSMYHN LCEVRRHFVW HETPKGYDSF YMTAYQLWLK RSSLRLSS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-47 | 76 | 359 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI29307.1 | 0 | 56 | 407 | 97 | 448 | unnamed protein product [Vitis vinifera] |
EMBL | CBI39073.1 | 0 | 60 | 406 | 108 | 445 | unnamed protein product [Vitis vinifera] |
RefSeq | XP_002265438.1 | 0 | 59 | 406 | 105 | 443 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002297901.1 | 0 | 10 | 407 | 41 | 456 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512716.1 | 0 | 55 | 407 | 74 | 425 | catalytic, putative [Ricinus communis] |