Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 27556.m000050 |
Family | GT41 |
Protein Properties | Length: 511 Molecular Weight: 55422.2 Isoelectric Point: 6.3505 |
Chromosome | Chromosome/Scaffold: 27556 Start: 7 End: 1539 |
Description | Tetratricopeptide repeat (TPR)-like superfamily protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT41 | 231 | 511 | 0 |
LEPERAPLHNNLGNVLRDQGLLDQATASYRQAVALDPGFAQAHSNLLLLLNTRPDVSLREQFDEARAFGERQSAKVLRVGHPPHASETKKRLRVGFVSGD LNSHPVGFFLESVLGHLDRERIELVAYATRQRDDAVSQRLMPHFSAWHDVSRLDDETCARRIRDDAVDILVDLSGHTNHNRLPVFAWKPAPVQATWLGYF ATTGLASIDYVIADRHVLPSDESSQFVEAPWHLPHSYLCFTPPPFDIEAGLLPAGAHGAITFGCFNHLVKLNDAVIALWSR |
Full Sequence |
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Protein Sequence Length: 511 Download |
MQAPADHESR SSGDVQMDGT AHAPSSAAPA FDAAAVLQAA FAHHQAGRTA EAAECYKLIL 60 QHDGAHADAL HFLGVLVCDV GNLPAGIDLI EKSIQLHPNA IYLNNLGNMR GRACNHQGAI 120 AAYRAALSLA PDYAEAHSNL GHALRQAGDS LAAVGSCTRA VELKPEFAQA WINLGNALLD 180 LGSDEDALDS YIKALALNPN DANAHNNVGN ILEKYGRAAR AAEAYRRALA LEPERAPLHN 240 NLGNVLRDQG LLDQATASYR QAVALDPGFA QAHSNLLLLL NTRPDVSLRE QFDEARAFGE 300 RQSAKVLRVG HPPHASETKK RLRVGFVSGD LNSHPVGFFL ESVLGHLDRE RIELVAYATR 360 QRDDAVSQRL MPHFSAWHDV SRLDDETCAR RIRDDAVDIL VDLSGHTNHN RLPVFAWKPA 420 PVQATWLGYF ATTGLASIDY VIADRHVLPS DESSQFVEAP WHLPHSYLCF TPPPFDIEAG 480 LLPAGAHGAI TFGCFNHLVK LNDAVIALWS R |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
cd00189 | TPR | 7.0e-10 | 169 | 295 | 127 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
cd00189 | TPR | 1.0e-14 | 103 | 200 | 98 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
cd00189 | TPR | 7.0e-15 | 135 | 216 | 82 | + Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans in various subcellular locations; involved in a variety of functions including protein-protein interactions, but common features in the interaction partners have not been defined; involved in chaperone, cell-cycle, transciption, and protein transport complexes; the number of TPR motifs varies among proteins (1,3-11,13 15,16,19); 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accomodate an alpha-helix of a target protein; it has been proposed that TPR proteins preferably interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes; examples of TPR-proteins include, Cdc16p, Cdc23p and Cdc27p components of the cyclosome/APC, the Pex5p/Pas10p receptor for peroxisomal targeting signals, the Tom70p co-receptor for mitochondrial targeting signals, Ser/Thr phosphatase 5C and the p110 subunit of O-GlcNAc transferase; three copies of the repeat are present here | ||
pfam13844 | Glyco_transf_41 | 2.0e-24 | 322 | 467 | 152 | + Glycosyl transferase family 41. This family of glycosyltransferases includes O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase, an enzyme which catalyzes the addition of O-GlcNAc to serine and threonine residues. In addition to its function as an O-GlcNAc transferase, human OGT, also appears to proteolytically cleave the epigenetic cell-cycle regulator HCF-1. | ||
COG3914 | Spy | 3.0e-59 | 143 | 510 | 390 | + Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones] |
Gene Ontology | |
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GO Term | Description |
GO:0005515 | protein binding |
GO:0042802 | identical protein binding |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 4gz6_D | 0 | 103 | 468 | 12 | 386 | A Chain A, Crystal Structure Of A Mutant T41s Of A Betagamma-Crystallin Domain From Clostridium Beijerinckii |
PDB | 4gz6_D | 0.0000000001 | 199 | 286 | 6 | 93 | A Chain A, Crystal Structure Of A Mutant T41s Of A Betagamma-Crystallin Domain From Clostridium Beijerinckii |
PDB | 4gz6_D | 0.000001 | 24 | 149 | 40 | 160 | A Chain A, Crystal Structure Of A Mutant T41s Of A Betagamma-Crystallin Domain From Clostridium Beijerinckii |
PDB | 4gz6_C | 0 | 103 | 468 | 12 | 386 | A Chain A, Crystal Structure Of A Mutant T41s Of A Betagamma-Crystallin Domain From Clostridium Beijerinckii |
PDB | 4gz6_C | 0.0000000001 | 199 | 286 | 6 | 93 | A Chain A, Crystal Structure Of A Mutant T41s Of A Betagamma-Crystallin Domain From Clostridium Beijerinckii |
Sequence Alignments (This image is cropped. Click for full image.) |
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