Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10015475 |
Family | GT24 |
Protein Properties | Length: 1694 Molecular Weight: 190454 Isoelectric Point: 5.1525 |
Chromosome | Chromosome/Scaffold: 860 Start: 122729 End: 136014 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1381 | 1628 | 0 |
INIFSIASGHLYERFLRIMILSVLKNTQRPVKFWFIKNYLSPQFKDVIPHMAEEYGFEYELITYKWPSWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIVRADMGELYDMDIKGRPLAYTPFCDNNKDMDGYKFWRQGFWKEHLRGRPYHISALYVVDLAKFRETAAGDNLRVFYETLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKSNAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1694 Download |
MTNRGTHTGS FTGLPLPDLS GGKDDLAVTK GTESSPSSES HTNKPLSLPR RRQLTAHFDN 60 LPYFPSRAIN VGSVFRSGIP LETQLQSVLE LSDDHGRVQI QFLCSDHRSL LMLFRAGSRL 120 WTESKAEECA GCCSNQMGGH PNFTGSWFLG MSATELLFLQ NCELLSKEWK DLYWEFIDIW 180 HKSQKDGSES YTAKDCLKRI VKIGSDLLSD PLASLFEFSL TLRSASPRLQ LYRQLAEESL 240 ASFPPSDDSI SNDSEGFLET AGNNEIKKSD PLLIGRNPSS PGGKCCWVDT GGRLFFDVSE 300 LQLWLRSTAA PAGDSFQQPE LFDFDHVHFD SHAGSPVAVL YGAIGTDCFL ELHSTLVAAA 360 KEGKVKYIVR PVLPCGCESK AHHCAAVGAR ESLNLAGYGV ELALKNMEYN AMDDSTVKKG 420 VTLEDPRTED LSQEDPKPEL TSDTLDVWEL KDLGHQTAQR IVQASNPLQA MQEINQNFPS 480 VVSSLSRMKL NDSVKDEITA NQRMIPPGKS LLALNGALLN IEDIDLYLLV DLAQQDLLLA 540 DRLSKMKVPQ STVRKLLSTM APQEASAFRV DFRSVNVHYI NNLEEDSMYK RWRSNLNEAV 600 DMIVSLYENN VPVRFGLILY SSDFLNKIEL NAGESHSSST EDKSSLIIRL FIYIKENYGV 660 QTAFQFLSNV NRLQLESEDV DEAPEMHHIE GAFVDTILPK AKSHPQDMLL KLLKEQTYKE 720 SSHESSKSVL KLGLSKLKCS LLMNGLVLDS TEDALMNAMN DELPRIQEQV YYGQITSRTD 780 VLDKFLSEGG ISRYNPQIIA EGKAKPRFIS LMSSVLGEES VINDINYLHT PDTVDDLKPV 840 TQLLVVDIAT KTGVKFLHEG IRYLIEGSKV SRLGVLFTAS KDVDLPSLLF MKAFQITASQ 900 YGHKEKVLMF LDHMSTYFEQ NYIFTSSGSV ESSQIFMDKI YELADANGLS LKAYKSALPE 960 SSIEDMTTYM SKVAQFLYRE LRLESGVNAV ITNGRVTIPS EGTFLSHDLQ LLESVEYKQR 1020 IKHIVDIIEE VEWQDEDPDL LTSKFVSDVV MCISSAMATR ERSSESARFE ILNGDYSAVI 1080 IENEGSGVHI DAVIDPLSPT GQKVASLLNV LKKYIQPSMR LILNPLSSLV DLPLKNYYRY 1140 VVPAMDDFSS TDHTVPGPKA YFENMPLSKT LTMNLDVPEP WLIEPVIAVH DMDNILLENL 1200 GDTRTMQAVF ELEALVLTGH CSEKDHEPPR GLQLILGTKS MPHFVDTIVM ANLGYWQMKA 1260 SPGVWYLQLA PGRSSELYAL NEDGVGNEDR HLSKRINIDD FRGKVVHLEV VKRKGREHDK 1320 LLVPSDDDSQ PHGREKGALD GWNSNFLKWA SGIIGVNGKS KNNESDVVAK KGKGGRHGTT 1380 INIFSIASGH LYERFLRIMI LSVLKNTQRP VKFWFIKNYL SPQFKDVIPH MAEEYGFEYE 1440 LITYKWPSWL HKQKEKQRII WAYKILFLDV IFPLSLEKVI FVDADQIVRA DMGELYDMDI 1500 KGRPLAYTPF CDNNKDMDGY KFWRQGFWKE HLRGRPYHIS ALYVVDLAKF RETAAGDNLR 1560 VFYETLSKDP NSLSNLDQDL PNYAQHTVPI FSLPQEWLWC ESWCGNATKS NAKTIDLCNN 1620 PMTKEPKLQG ARRIVPEWVD LDSEARRFTA KILGEEEPED SVVTTATTKQ PETQNPSSRE 1680 TEPETDLETK AEL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01501 | Glyco_transf_8 | 4.0e-7 | 1385 | 1580 | 205 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd04194 | GT8_A4GalT_like | 3.0e-15 | 1381 | 1597 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 4.0e-59 | 1381 | 1628 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 2.0e-77 | 1047 | 1252 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 3.0e-176 | 1381 | 1628 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAG51883.1 | 0 | 157 | 1693 | 46 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
GenBank | EEE57527.1 | 0 | 200 | 1682 | 63 | 1596 | hypothetical protein OsJ_07839 [Oryza sativa Japonica Group] |
RefSeq | NP_177278.3 | 0 | 157 | 1693 | 46 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002268972.1 | 0 | 167 | 1693 | 59 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002529534.1 | 0 | 157 | 1578 | 49 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO415354 | 550 | 1123 | 1657 | 0 |
HO797114 | 379 | 1317 | 1694 | 0 |
GO883503 | 315 | 1341 | 1655 | 0 |
DR944618 | 278 | 1374 | 1651 | 0 |
HO415354 | 141 | 981 | 1119 | 5e-19 |
Sequence Alignments (This image is cropped. Click for full image.) |
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