Basic Information | |
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Species | Linum usitatissimum |
Cazyme ID | Lus10019946 |
Family | GT24 |
Protein Properties | Length: 1469 Molecular Weight: 165172 Isoelectric Point: 5.0786 |
Chromosome | Chromosome/Scaffold: 23 Start: 27131 End: 40093 |
Description | UDP-glucose:glycoprotein glucosyltransferases;transferases, transferring hexosyl groups;transferases, transferring glycosyl groups |
View CDS |
External Links |
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CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT24 | 1157 | 1404 | 0 |
INIFSIASGHLYERFLRIMILSVLKNTQRPVKFWFIKNYLSPQFKDVIPHMAEEYGFEYELITYKWPSWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIVRADMGELYDMDIKGRPLAYTPFCDNNKDMDGYKFWRQGFWKEHLRGRPYHISALYVVDLAKFRETAAGDNLRVFYETLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKSKAKTIDLCNNPMTKEPKL |
Full Sequence |
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Protein Sequence Length: 1469 Download |
MATAGFRSSF CVLIIGACLC FSALDPVCGQ NRWPKNVQVA VRAKWEGTPI LLEAGELLSK 60 EWKDLYWEFI DIWHKSEKDG SESYTAKDCL KRIVKIGSDL LSDPLASLFE FSLTLRSASP 120 RLQLYQQLAE ESLASFPPSD DSISNDADNN EIKKSDPLLV GRNPSSPGGE CCWVDTGGRL 180 FFDVSELQLW LRSTAAPAGD SFQQPELFDF DHVHFDSHAG SPVAVLYGAI GTDCFLELHS 240 TLVAAAKEFQ GKVKYIVRPV LPSGCESKVH HCAAVGARES LNLAGYGVEL ALKNMEYNAM 300 DDSTVKKDLG HQTAQRIVQA SNPLQAMQEI NQNFPSVVSS LSRMKINDSV KDEITANQRM 360 IPPGKSLLAL NGALLNIEDI DLYLLVDLVQ QDLLLADRLS KMKVPQSTVR KLLSTMAPQE 420 SSAFRVDFRS ANVHYINNLE EDSMYKRWRS NLNEVNRLQL ESGDVDEAAE MHHIEGAFVD 480 TILPKAKSHP QDMLLKLLKE QTYKESSHES SKSVLKLGLS KLKCSLLMNG LVLDSTEDAL 540 MNAMNDELPR IQEQVYYGHI TSRTDVLDKF LSEGGISRYN PQIIAEGKAK PRFISLMSSV 600 LGEESVINDI NYLHTPDTVD DLKPVTQLLV VDIATKTGVK LLHEGIRYLI EGSKVSRLGV 660 LFTASKDVDL PSLLFMKAFQ ITASQYGHKE KVLIFLDHMS TYFEQNYVFT SSGSVESSQI 720 FIDEIYELAD ANGLSLKAYK SALPESSIEE MTTYMSKVAQ FLYRELRIES GLNAVITNGR 780 VMIPSEGTFL SHDLQLLESV EYKQRIKHIV DIIEEVEWQD EDPDLLTSKF VSDVVMCVSS 840 AMATRERSSE SARFEILNGD YSAVIIENEG SGVHIDAVID PLSPIGQKSS LVDLPLKNYY 900 RYVVPAMDDF SSTDHTVPGP KAFFANMPLS KTLTMNLDVP EPWLIEPVIA VLILGCYRFL 960 GECLSHDMDN ILLENLGDTR TMQAVFELEA LVLTGHCSEK DHEPPRGLQL ILGTKSMPHF 1020 VDTIVMANLG YWQMKASPGV WYLQLAPGRS SELYALNEDG VGNEDQHLSK RINIDDFRGK 1080 VVHLEVVKRK GREHDKLLVP SDDDSQSHGR EKGALDGWNS NFLKWASGII GVNGKSKKNE 1140 NDVVAKKGKG GRHGTTINIF SIASGHLYER FLRIMILSVL KNTQRPVKFW FIKNYLSPQF 1200 KDVIPHMAEE YGFEYELITY KWPSWLHKQK EKQRIIWAYK ILFLDVIFPL SLEKVIFVDA 1260 DQIVRADMGE LYDMDIKGRP LAYTPFCDNN KDMDGYKFWR QGFWKEHLRG RPYHISALYV 1320 VDLAKFRETA AGDNLRVFYE TLSKDPNSLS NLDQDLPNYA QHTVPIFSLP QEWLWCESWC 1380 GNATKSKAKT IDLCNNPMTK EPKLQGARRI VPEWVDLDSE ARQFTEKILG EEEPEDAVTT 1440 TTSKQPETQN PSTTETEPET DLETKAEL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam01501 | Glyco_transf_8 | 5.0e-7 | 1161 | 1356 | 205 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
cd04194 | GT8_A4GalT_like | 3.0e-15 | 1157 | 1373 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
cd00505 | Glyco_transf_8 | 2.0e-58 | 1157 | 1404 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
pfam06427 | UDP-g_GGTase | 1.0e-62 | 832 | 1028 | 226 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
cd06432 | GT8_HUGT1_C_like | 5.0e-178 | 1157 | 1404 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. |
Gene Ontology | |
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GO Term | Description |
GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
GO:0006486 | protein glycosylation |
GO:0016757 | transferase activity, transferring glycosyl groups |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_177278.3 | 0 | 1 | 309 | 1 | 278 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | NP_177278.3 | 0 | 307 | 455 | 333 | 481 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | NP_177278.3 | 0 | 452 | 1468 | 589 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002268972.1 | 0 | 6 | 455 | 5 | 485 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
RefSeq | XP_002268972.1 | 0 | 452 | 1468 | 592 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |