| Basic Information | |
|---|---|
| Species | Setaria italica |
| Cazyme ID | Si036592m |
| Family | CE11 |
| Protein Properties | Length: 329 Molecular Weight: 35426.4 Isoelectric Point: 6.5033 |
| Chromosome | Chromosome/Scaffold: 9 Start: 52526825 End: 52531609 |
| Description | UDP-3-O-acyl N-acetylglycosamine deacetylase family protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| CE11 | 26 | 298 | 0 |
| QQTLAAAVSRSGVGLHSGARVTATLLPTYAGEGRYFQVEGKEEARVAAEVGNAEPRSQLCTTLQRGEGCGPRIRTVEHLLSAMEALGVDNCRVEVIGGDE IPLLDGSAQEWVEAIRSAGLCAAEDTGGQKLEKLAPQIHEPVYLQRDDCFVAAFPSSQIHITYGIDFPKVPAIGCQWFSTFLDANIYSSKIAPARTFCIF EEIEKMRGAGLIKGGSLENAMVCSMSGGWLNPPVRFEDEPCRHKILDLIGDFSLLAQNGNQGFPIAHIIAYKE | |||
| Full Sequence |
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| Protein Sequence Length: 329 Download |
| MSTAATRALK SVSHAVFSWK PTGRPQQTLA AAVSRSGVGL HSGARVTATL LPTYAGEGRY 60 FQVEGKEEAR VAAEVGNAEP RSQLCTTLQR GEGCGPRIRT VEHLLSAMEA LGVDNCRVEV 120 IGGDEIPLLD GSAQEWVEAI RSAGLCAAED TGGQKLEKLA PQIHEPVYLQ RDDCFVAAFP 180 SSQIHITYGI DFPKVPAIGC QWFSTFLDAN IYSSKIAPAR TFCIFEEIEK MRGAGLIKGG 240 SLENAMVCSM SGGWLNPPVR FEDEPCRHKI LDLIGDFSLL AQNGNQGFPI AHIIAYKELR 300 SLSLPTSHQR KCVQVVELGF ADRPSGAI* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PRK13188 | PRK13188 | 1.0e-59 | 26 | 297 | 303 | + bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed | ||
| TIGR00325 | lpxC | 3.0e-71 | 26 | 297 | 274 | + UDP-3-0-acyl N-acetylglucosamine deacetylase. UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]. | ||
| pfam03331 | LpxC | 2.0e-86 | 26 | 297 | 280 | + UDP-3-O-acyl N-acetylglycosamine deacetylase. The enzymes in this family catalyze the second step in the biosynthetic pathway for lipid A. | ||
| COG0774 | LpxC | 3.0e-87 | 26 | 297 | 279 | + UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane] | ||
| PRK13186 | lpxC | 6.0e-100 | 26 | 297 | 278 | + UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008759 | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity |
| GO:0009245 | lipid A biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAN52736.1 | 0 | 1 | 297 | 1 | 287 | Hypothetical protein [Oryza sativa Japonica Group] |
| GenBank | ABF94722.1 | 0 | 1 | 284 | 1 | 280 | UDP-3-0-acyl N-acetylglucosamine deacetylase family protein, expressed [Oryza sativa (japonica cultivar-group)] |
| GenBank | EEE58623.1 | 0 | 1 | 297 | 1 | 294 | hypothetical protein OsJ_09977 [Oryza sativa Japonica Group] |
| RefSeq | NP_001049426.1 | 0 | 1 | 297 | 1 | 293 | Os03g0223900 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002468246.1 | 0 | 1 | 302 | 1 | 302 | hypothetical protein SORBIDRAFT_01g042410 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1xxe_A | 6e-35 | 26 | 281 | 4 | 239 | A Chain A, Rdc Refined Solution Structure Of The AalpxcTU-514 Complex |
| PDB | 4fw7_D | 2e-34 | 26 | 302 | 7 | 277 | A Chain A, Rdc Refined Solution Structure Of The AalpxcTU-514 Complex |
| PDB | 4fw7_C | 2e-34 | 26 | 302 | 7 | 277 | A Chain A, Rdc Refined Solution Structure Of The AalpxcTU-514 Complex |
| PDB | 4fw7_B | 2e-34 | 26 | 302 | 7 | 277 | A Chain A, Rdc Refined Solution Structure Of The AalpxcTU-514 Complex |
| PDB | 4fw7_A | 2e-34 | 26 | 302 | 7 | 277 | A Chain A, Rdc Refined Solution Structure Of The AalpxcTU-514 Complex |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| lipid IVA biosynthesis | UDPACYLGLCNACDEACETYL-RXN | EC-3.5.1.108 | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| HX136805 | 260 | 7 | 266 | 0 |
| CK207177 | 250 | 7 | 256 | 0 |
| CT850072 | 297 | 1 | 297 | 0 |
| CA246559 | 181 | 122 | 302 | 0 |
| CA238382 | 181 | 122 | 302 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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