CAZyme Information: MGYG000004628_00051

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; Lawsonibacter
• CAZyme ID: MGYG000004628_00051
• CAZy Family: CBM54
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1630		176394.15	4.2717

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004628	2940804	MAG	Germany	Europe

• Gene Location: Start: 50771; End: 55663 Strand: +

Full Sequence      

MTGWMKWMKRLAGRAGTALLVVILAVAMTAAASAASYMQPYLDKVVEWGVMRGDLEGNLN
EDNYITRAEFSTMVNRAFGYDKTGPTPFRDVPENSWYAEDVGIAYNVGYIAGTSATTFSP
NDNVTREQAALILARILMLQPQVGENTMFTDSRSMENWSRGYIASVAQQGLISGYPDGRF
GPKDNLTRGQAAIILVNALGTPLMEAGDYTLGSVWGNVTITQSGTTLRNTVIGGDLYITE
GVDLGHVTLENVTVLGKIVVCGGGTSEGGEDSIILRNVTAPELLVDNLDNHLLSLKVEGD
GKIDQAYIRTSAYLADNTVDGCGIAKITMDGEEDEALTLAGNVKEVINKAPNTSVSLASG
QADTITVDENAVGSTLDIAAGSRVDNVNLDTGVDVTGGGDIGKLTVNSNGSTVSMLPDQI
TIRPGNTANINGEVMDSAAAAESSADPRLYAGYPKMKDLAPTSGTAVFSANKKGTVYWAL
TAVTDGSVTADELVNPSAYNPKVVKSGTVSLTGSGKEGTSNISGLTSDGSYYLSAVFVDA
RDNRSPLKVISFTTPDNTKPDFASGYPYLSKVTKNSAQVTTMATKSCRLYWAVLPKGASA
PTANDFKANAVSGNLGFGSTDVIKNTAYSFDVNNVPLEELESYDLYLWLTDVDNGQSSAV
KKLSFTTVDGTPPKFNTEPTINKVDKTSVGLYANLNEAGTLYWVVVEHGTTYPKPLAGQS
GDVDWTSDTAKLQVSAGMNALKSGKVSMTEGKDVSFTVSGLEAEKAYDLYYVAQDKAGNY
TASIGMIEIHTLDSNAPTVTQEFTKYNGTDTTRPLPDSDVRLVFSESVQTNDTYTPLVDL
YKEVTDAANMGAAEESARQKMAAALSKAIYLYQVSSDGQTEKLEGYTGSDKNTDDWTIDY
RYAVITTEEGKTVVTFPNGKGINLKSGASYYFEIQADSIADTSSAVNVMGREKLDQFTTV
FAVVNLTARNENTIEKYVDQAGTEHELEAKDAIPVDLSWRLSPVSTDKVDDSIDWDMLIW
SDTSVTLQLFYREVGSSTTTWKLLGEKEIPVPDNTNGYLGVSLTRHFLQNSNNPDFDQLN
ILKEGTNYEYAISFTKVAGLSDRSTWSQRLNMKVNVVAGSNNDLSFLSGEVTQDNWDEAL
KTGVTNIGQPSDFSLRKQFTDNVAPTFAGEYPKLDAGDSAVNMSLMLDRPGTVYYVVAPL
GYVGTTDNKNNIYNNTDAGITNWENLPENGLDDDINDPDDPYPAILTQPDYLNIVNASSN
YRNEKIKYGSVTCGSSVETKLVEGLDKQTKYIAYFVLQGTSQTYSRVLAYRFETTDVAKP
KLTLTDFSPSVNFKTDSTADVNYALVASNEIPSSLKVDFGSVVDSTRKKEWEDYKKTLDT
DTNTSVLWALLTTYKTGYTVFDEFAGDGIRTTVEEFISGVSSMGVDVANRGSTELTQANN
YSKEQNFTANMKGATYYYCLATAVSPLGSEMSFAAVAGIHIRDTEPPKLISVNTDARPST
GNLYSGTVTFVFDEPVYQLVNQNGVDQKPMQIWQTKYSINTDDQKIAVNLPDIISSSLPD
NFFCETNVRVPSTSLTLTFTNIPLNTTLVLFNNSYICDENSNSTREILSFTLQSGVPIGN
IQNGIAFVQQ

Enzyme Prediction     

No EC number prediction in MGYG000004628_00051.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
CBM54	202	312	3.7e-23	0.9122807017543859

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
NF033190	inl_like_NEAT_1	1.22e-13	43	195	541	687	NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading.
pfam00395	SLH	2.21e-09	149	191	1	42	S-layer homology domain.
pfam00395	SLH	1.55e-08	88	129	1	42	S-layer homology domain.
NF033190	inl_like_NEAT_1	4.36e-06	62	199	616	752	NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading.
NF033190	inl_like_NEAT_1	3.93e-05	42	133	655	748	NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QIA32369.1	0.0	36	1630	36	1615
QQR07714.1	0.0	36	1630	36	1615
BCK84769.1	0.0	36	1517	44	1536
QQR30851.1	5.20e-236	36	1517	38	1670
ASB41592.1	5.20e-236	36	1517	38	1670

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5GZT_A	1.04e-08	188	264	33	106	CrystalStructure of Chitinase ChiW from Paenibacillus sp. str. FPU-7 Reveals a Novel Type of Bacterial Cell-Surface-Expressed Multi-Modular Enzyme Machinery [Paenibacillus sp. FPU-7]
6BT4_A	1.22e-08	88	208	26	150	Crystalstructure of the SLH domain of Sap from Bacillus anthracis in complex with a pyruvylated SCWP unit [Bacillus anthracis]
3PYW_A	1.24e-08	88	208	5	129	Thestructure of the SLH domain from B. anthracis surface array protein at 1.8A [Bacillus anthracis]
4AQ1_A	4.66e-07	97	198	11	109	Structureof the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6 [Geobacillus stearothermophilus]
4AQ1_C	4.66e-07	97	198	11	109	Structureof the SbsB S-layer protein of Geobacillus stearothermophilus PV72p2 in complex with nanobody KB6 [Geobacillus stearothermophilus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P38536	4.45e-18	50	199	1702	1855	Amylopullulanase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=amyB PE=3 SV=2
P38537	2.16e-16	36	205	41	216	Surface-layer 125 kDa protein OS=Lysinibacillus sphaericus OX=1421 PE=3 SV=1
P38535	9.24e-15	50	199	928	1081	Exoglucanase XynX OS=Acetivibrio thermocellus OX=1515 GN=xynX PE=3 SV=1
P19424	5.72e-14	36	199	48	214	Endoglucanase OS=Bacillus sp. (strain KSM-635) OX=1415 PE=1 SV=1
C6CRV0	6.90e-14	42	195	1296	1455	Endo-1,4-beta-xylanase A OS=Paenibacillus sp. (strain JDR-2) OX=324057 GN=xynA1 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000739	0.998378	0.000234	0.000218	0.000198	0.000184

TMHMM  Annotations     

start	end
12	34