You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001626_00599
You are here: Home > Sequence: MGYG000001626_00599
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phascolarctobacterium sp900544795 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Phascolarctobacterium; Phascolarctobacterium sp900544795 | |||||||||||
| CAZyme ID | MGYG000001626_00599 | |||||||||||
| CAZy Family | CE11 | |||||||||||
| CAZyme Description | UDP-3-O-acyl-N-acetylglucosamine deacetylase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 72959; End: 73801 Strand: - | |||||||||||
Full Sequence Download help
| MKEIMQQTLA APVKYSGIGL HSGKEVIMQI LPAAENTGIV FVRTDLPGCP EIKALAENVS | 60 |
| STIKATTVSV DGAEVFTVEH LMAALSMMGI DNCRIEMSSP EPPVTDGSAA VFCELIKKAG | 120 |
| RVEQQEKRKI YAVEKAFAVY EGDKYVTIQP YDGYRISFVS VNAHPALGTQ YFDIELTEEN | 180 |
| FLQEIAAART VGFMSEIKQL QQMGLGLGGS IENVVIFDND KILSETRFDD ELIRHKILDV | 240 |
| IGDLYLLGHL RGHIIAVKSG HAFNSCLAKQ IQAYRIKEEE | 280 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| CE11 | 6 | 272 | 2.1e-100 | 0.992619926199262 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam03331 | LpxC | 2.81e-147 | 6 | 273 | 1 | 271 | UDP-3-O-acyl N-acetylglycosamine deacetylase. The enzymes in this family catalyze the second step in the biosynthetic pathway for lipid A. |
| PRK13186 | lpxC | 3.18e-138 | 4 | 280 | 2 | 285 | UDP-3-O-acyl-N-acetylglucosamine deacetylase. |
| COG0774 | LpxC | 8.07e-118 | 3 | 276 | 1 | 284 | UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell wall/membrane/envelope biogenesis]. |
| PRK13188 | PRK13188 | 8.78e-94 | 4 | 280 | 3 | 306 | bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; Reviewed |
| TIGR00325 | lpxC | 1.38e-92 | 4 | 273 | 1 | 273 | UDP-3-0-acyl N-acetylglucosamine deacetylase. UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| BBG63219.1 | 2.51e-177 | 1 | 280 | 1 | 280 |
| QNP78243.1 | 1.20e-174 | 5 | 280 | 1 | 276 |
| QTV78319.1 | 3.33e-141 | 2 | 279 | 5 | 282 |
| VEG93959.1 | 2.93e-108 | 6 | 271 | 5 | 270 |
| BBU36768.1 | 5.90e-108 | 6 | 271 | 5 | 270 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5U39_A | 2.22e-72 | 4 | 273 | 4 | 278 | Pseudomonasaeruginosa LpxC in complex with CHIR-090 [Pseudomonas aeruginosa PAO1] |
| 4J3D_A | 2.36e-72 | 4 | 273 | 2 | 276 | Pseudomonasaeruginosa LpxC in complex with a hydroxamate inhibitor [Pseudomonas aeruginosa PAO1],4J3D_B Pseudomonas aeruginosa LpxC in complex with a hydroxamate inhibitor [Pseudomonas aeruginosa PAO1] |
| 5U3B_A | 2.51e-72 | 4 | 273 | 2 | 276 | Pseudomonasaeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],5U3B_B Pseudomonas aeruginosa LpxC in complex with NVS-LPXC-01 [Pseudomonas aeruginosa PAO1],6MAE_A CHAIN A. UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase PA-LPXC Complexed with (R)-3-((S)-3-(4-(cyclopropylethynyl)phenyl)-2-oxooxazolidin-5-yl)-N-hydroxy-2-methyl-2-(methylsulfonyl)propenamide [Pseudomonas aeruginosa PAO1] |
| 7K99_A | 2.83e-72 | 4 | 273 | 2 | 276 | CrystalStructure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor 19 [Pseudomonas aeruginosa PAO1],7K99_C Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor 19 [Pseudomonas aeruginosa PAO1],7K9A_A Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor [Pseudomonas aeruginosa PAO1],7K9A_C Crystal Structure of P. aeruginosa LpxC with N-Hydroxyformamide inhibitor [Pseudomonas aeruginosa PAO1] |
| 6MO4_A | 2.83e-72 | 4 | 273 | 6 | 280 | Co-Crystalstructure of P. aeruginosa LpxC-50067 complex [Pseudomonas aeruginosa PAO1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| C1D5L0 | 8.44e-77 | 4 | 273 | 2 | 277 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Laribacter hongkongensis (strain HLHK9) OX=557598 GN=lpxC PE=3 SV=1 |
| A1U3F2 | 5.45e-75 | 4 | 273 | 2 | 276 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8) OX=351348 GN=lpxC PE=3 SV=1 |
| Q1D2K0 | 4.20e-74 | 6 | 273 | 8 | 278 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Myxococcus xanthus (strain DK1622) OX=246197 GN=lpxC PE=3 SV=1 |
| Q47AB0 | 4.52e-74 | 4 | 271 | 2 | 274 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Dechloromonas aromatica (strain RCB) OX=159087 GN=lpxC PE=3 SV=1 |
| A4SV81 | 7.04e-73 | 6 | 271 | 4 | 274 | UDP-3-O-acyl-N-acetylglucosamine deacetylase OS=Polynucleobacter asymbioticus (strain DSM 18221 / CIP 109841 / QLW-P1DMWA-1) OX=312153 GN=lpxC PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000069 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |