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CAZyme Information: MGYG000000122_00513

You are here: Home > Sequence: MGYG000000122_00513

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Staphylococcus epidermidis
Lineage Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus epidermidis
CAZyme ID MGYG000000122_00513
CAZy Family CE9
CAZyme Description N-acetylglucosamine-6-phosphate deacetylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
390 MGYG000000122_2|CGC4 42462.11 6.3825
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000122 2560588 Isolate Canada North America
Gene Location Start: 186508;  End: 187680  Strand: +

Full Sequence      Download help

MSEYVLTNGI  VYTENEMINN  GYVHIKDGKI  LDVGKCPFHP  SSSHNTIDII  DVKKRHILPG60
FIDIHIHGGY  GEDAMDASEQ  GLQHLAESLL  SEGTTSFLAT  TMTQSTVNIE  RALQTIAKYT120
QQQDVTNAAE  IVGVHLEGPF  ISEHKVGAQH  PQFVQRPTVD  KIKSFQEVAN  GLIKIITYAP180
EVDGATETLK  TMKNDIIFSI  GHTVATFDQA  NTAVSHGAKH  ITHLYNAATG  FQHREPGVFG240
AAWLNQGLHT  EMIVDGVHSH  PASIALAYRL  KGNQSCYLIT  DAMRAKGMPE  GHYDLGGQDV300
IVKGSEARLS  SGALAGSILK  MNEGLKNLIQ  FTGDTIEHLW  RVTSLNQAIT  LGIDDIKGSI360
KIGKDADIVI  IDDACNVETT  IKNGKYHAFK  390

Enzyme Prediction      help

No EC number prediction in MGYG000000122_00513.

CAZyme Signature Domains help

Created with Snap19395878971171361561751952142342532732923123313513707384CE9
Family Start End Evalue family coverage
CE9 7 384 2.1e-131 0.9946380697050938

CDD Domains      download full data without filtering help

Created with Snap19395878971171361561751952142342532732923123313513704384NagA4389NagA4385nagA4389nagA57385Amidohydro_1
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd00854 NagA 9.31e-166 4 384 1 374
N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.
COG1820 NagA 2.82e-154 4 389 2 380
N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism].
TIGR00221 nagA 9.69e-113 4 385 5 380
N-acetylglucosamine-6-phosphate deacetylase. [Central intermediary metabolism, Amino sugars]
PRK11170 nagA 6.55e-67 4 389 2 381
N-acetylglucosamine-6-phosphate deacetylase; Provisional
pfam01979 Amidohydro_1 7.70e-20 57 385 2 333
Amidohydrolase family. This family of enzymes are a a large metal dependent hydrolase superfamily. The family includes Adenine deaminase EC:3.5.4.2 that hydrolyzes adenine to form hypoxanthine and ammonia. Adenine deaminases reaction is important for adenine utilisation as a purine and also as a nitrogen source. This family also includes dihydroorotase and N-acetylglucosamine-6-phosphate deacetylases, EC:3.5.1.25 These enzymes catalyze the reaction N-acetyl-D-glucosamine 6-phosphate + H2O <=> D-glucosamine 6-phosphate + acetate. This family includes the catalytic domain of urease alpha subunit. Dihydroorotases (EC:3.5.2.3) are also included.

CAZyme Hits      help

Created with Snap19395878971171361561751952142342532732923123313513701390QQF50970.1|CE91390QKN63662.1|CE91390QRJ03751.1|CE91390QRJ18987.1|CE91390AIR83006.1|CE9
Hit ID E-Value Query Start Query End Hit Start Hit End
QQF50970.1 2.96e-286 1 390 1 390
QKN63662.1 2.96e-286 1 390 1 390
QRJ03751.1 2.96e-286 1 390 1 390
QRJ18987.1 2.96e-286 1 390 1 390
AIR83006.1 2.96e-286 1 390 1 390

PDB Hits      download full data without filtering help

Created with Snap193958789711713615617519521423425327329231233135137013842VHL_A213851O12_A253857NUT_A43863EGJ_A23866FV3_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2VHL_A 6.54e-107 1 384 1 384
TheThree-dimensional structure of the N-Acetylglucosamine-6- phosphate deacetylase from Bacillus subtilis [Bacillus subtilis],2VHL_B The Three-dimensional structure of the N-Acetylglucosamine-6- phosphate deacetylase from Bacillus subtilis [Bacillus subtilis]
1O12_A 2.86e-63 21 385 30 370
Crystalstructure of N-acetylglucosamine-6-phosphate deacetylase (TM0814) from Thermotoga maritima at 2.5 A resolution [Thermotoga maritima],1O12_B Crystal structure of N-acetylglucosamine-6-phosphate deacetylase (TM0814) from Thermotoga maritima at 2.5 A resolution [Thermotoga maritima]
7NUT_A 6.91e-53 25 385 33 399
ChainA, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens],7NUT_B Chain B, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens],7NUU_A Chain A, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens],7NUU_B Chain B, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens]
3EGJ_A 1.38e-52 4 386 5 378
N-acetylglucosamine-6-phosphatedeacetylase from Vibrio cholerae. [Vibrio cholerae],3EGJ_B N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae. [Vibrio cholerae],3IV8_A N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate [Vibrio cholerae],3IV8_B N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate [Vibrio cholerae],3IV8_C N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate [Vibrio cholerae],3IV8_D N-acetylglucosamine-6-phosphate deacetylase from Vibrio cholerae complexed with fructose 6-phosphate [Vibrio cholerae]
6FV3_A 7.71e-47 2 386 15 391
Crystalstructure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155],6FV3_B Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155],6FV3_C Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155],6FV3_D Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155]

Swiss-Prot Hits      download full data without filtering help

Created with Snap19395878971171361561751952142342532732923123313513701384sp|O34450|NAGA_BACSU23385sp|Q84F86|NAGA_LYSSH48385sp|P96166|NAGA_VIBFU4389sp|Q8XAC3|AGAA_ECO5725385sp|Q6P0U0|NAGA_DANRE
Hit ID E-Value Query Start Query End Hit Start Hit End Description
O34450 3.58e-106 1 384 1 384
N-acetylglucosamine-6-phosphate deacetylase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagA PE=1 SV=1
Q84F86 3.50e-87 23 385 25 380
N-acetylglucosamine-6-phosphate deacetylase OS=Lysinibacillus sphaericus OX=1421 GN=nagA PE=2 SV=1
P96166 2.03e-66 48 385 48 383
N-acetylglucosamine-6-phosphate deacetylase OS=Vibrio furnissii OX=29494 GN=manD PE=3 SV=1
Q8XAC3 7.43e-64 4 389 3 377
N-acetylgalactosamine-6-phosphate deacetylase OS=Escherichia coli O157:H7 OX=83334 GN=agaA PE=1 SV=2
Q6P0U0 4.79e-57 25 385 33 399
N-acetylglucosamine-6-phosphate deacetylase OS=Danio rerio OX=7955 GN=amdhd2 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000048 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000122_00513.