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CAZyme Information: MGYG000002169_00350

You are here: Home > Sequence: MGYG000002169_00350

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-1435 sp000433775
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-314; CAG-1435; CAG-1435 sp000433775
CAZyme ID MGYG000002169_00350
CAZy Family CE9
CAZyme Description N-acetylglucosamine-6-phosphate deacetylase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
361 MGYG000002169_5|CGC1 39141.94 6.0014
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002169 1570892 MAG Denmark Europe
Gene Location Start: 55580;  End: 56665  Strand: -

Full Sequence      Download help

MILYKNGLAL  LGDKLVKTDI  VANHGKIIEI  STEIVPDEQT  EVVDCTNRYI  LPALVDIHTH60
GANGYDFNTA  DTDGMKKILD  FYIAHGVGTV  FPTVMTDDEE  RICHQLELIV  QLAKDYPEIK120
GIHLEGPFLS  EKFCGAMPVQ  HLRNPSADLF  FKFQKHANGM  IKIVTVAPEL  PKAVEFIGEI180
SDTGVVVSLG  HSGANGETVQ  KAIKAGAKSF  THWGNAMSQL  DRHDLNMAGS  AMLSDNFCEV240
ICDGKHVQKD  VFRLLVRTKG  LDKVVCITDS  IMATGLPDGD  YTLAGNDVVV  VNGDARLKSN300
GVRAGSTLDA  YTGLANAVSF  TGLPLHQAIR  MWTVNPARLV  GLSHRIGTIE  VGKDADFILF360
G361

Enzyme Prediction      help

No EC number prediction in MGYG000002169_00350.

CAZyme Signature Domains help

Created with Snap18365472901081261441621801982162342522702883063243427360CE9
Family Start End Evalue family coverage
CE9 7 360 1.2e-113 0.9544235924932976

CDD Domains      download full data without filtering help

Created with Snap18365472901081261441621801982162342522702883063243422360NagA1360NagA1360nagA19360nagA49360Amidohydro_1
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd00854 NagA 2.25e-131 2 360 1 361
N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to amino-sugar-nucleotides, which is needed for cell wall peptidoglycan and teichoic acid biosynthesis. Deacetylation of N-acetylglucosamine is also important in lipopolysaccharide synthesis and cell wall recycling.
COG1820 NagA 9.37e-106 1 360 1 362
N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism].
TIGR00221 nagA 2.04e-77 1 360 4 366
N-acetylglucosamine-6-phosphate deacetylase. [Central intermediary metabolism, Amino sugars]
PRK11170 nagA 1.57e-45 19 360 14 363
N-acetylglucosamine-6-phosphate deacetylase; Provisional
pfam01979 Amidohydro_1 8.51e-19 49 360 1 308
Amidohydrolase family. This family of enzymes are a a large metal dependent hydrolase superfamily. The family includes Adenine deaminase EC:3.5.4.2 that hydrolyzes adenine to form hypoxanthine and ammonia. Adenine deaminases reaction is important for adenine utilisation as a purine and also as a nitrogen source. This family also includes dihydroorotase and N-acetylglucosamine-6-phosphate deacetylases, EC:3.5.1.25 These enzymes catalyze the reaction N-acetyl-D-glucosamine 6-phosphate + H2O <=> D-glucosamine 6-phosphate + acetate. This family includes the catalytic domain of urease alpha subunit. Dihydroorotases (EC:3.5.2.3) are also included.

CAZyme Hits      help

Created with Snap183654729010812614416218019821623425227028830632434241358ANU48011.1|CE941358QQR03992.1|CE917359ASM68821.1|CE96357AEE17798.1|CE95349QUH29416.1|CE9
Hit ID E-Value Query Start Query End Hit Start Hit End
ANU48011.1 1.41e-92 41 358 41 362
QQR03992.1 1.70e-92 41 358 47 368
ASM68821.1 2.35e-92 17 359 20 365
AEE17798.1 1.28e-90 6 357 12 367
QUH29416.1 2.20e-89 5 349 4 348

PDB Hits      download full data without filtering help

Created with Snap1836547290108126144162180198216234252270288306324342233592VHL_A503596FV3_A503596FV4_A43597NUT_A383606JKU_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2VHL_A 2.16e-54 23 359 27 370
TheThree-dimensional structure of the N-Acetylglucosamine-6- phosphate deacetylase from Bacillus subtilis [Bacillus subtilis],2VHL_B The Three-dimensional structure of the N-Acetylglucosamine-6- phosphate deacetylase from Bacillus subtilis [Bacillus subtilis]
6FV3_A 2.05e-45 50 359 64 375
Crystalstructure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155],6FV3_B Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155],6FV3_C Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155],6FV3_D Crystal structure of N-acetyl-D-glucosamine-6-phosphate deacetylase from Mycobacterium smegmatis. [Mycolicibacterium smegmatis MC2 155]
6FV4_A 2.98e-44 50 359 64 375
Thestructure of N-acetyl-D-glucosamine-6-phosphate deacetylase D267A mutant from Mycobacterium smegmatis in complex with N-acetyl-D-glucosamine-6-phosphate [Mycolicibacterium smegmatis MC2 155],6FV4_B The structure of N-acetyl-D-glucosamine-6-phosphate deacetylase D267A mutant from Mycobacterium smegmatis in complex with N-acetyl-D-glucosamine-6-phosphate [Mycolicibacterium smegmatis MC2 155]
7NUT_A 9.85e-43 4 359 15 384
ChainA, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens],7NUT_B Chain B, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens],7NUU_A Chain A, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens],7NUU_B Chain B, N-acetylglucosamine-6-phosphate deacetylase [Homo sapiens]
6JKU_A 1.53e-40 38 360 56 377
Crystalstructure of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella Multocida [Pasteurella multocida],6JKU_B Crystal structure of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella Multocida [Pasteurella multocida],6JKU_C Crystal structure of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella Multocida [Pasteurella multocida],6JKU_D Crystal structure of N-acetylglucosamine-6-phosphate deacetylase from Pasteurella Multocida [Pasteurella multocida]

Swiss-Prot Hits      download full data without filtering help

Created with Snap183654729010812614416218019821623425227028830632434223359sp|O34450|NAGA_BACSU19359sp|Q84F86|NAGA_LYSSH50358sp|P96166|NAGA_VIBFU1359sp|A7MBC0|NAGA_BOVIN14359sp|Q6P0U0|NAGA_DANRE
Hit ID E-Value Query Start Query End Hit Start Hit End Description
O34450 1.18e-53 23 359 27 370
N-acetylglucosamine-6-phosphate deacetylase OS=Bacillus subtilis (strain 168) OX=224308 GN=nagA PE=1 SV=1
Q84F86 4.81e-49 19 359 24 365
N-acetylglucosamine-6-phosphate deacetylase OS=Lysinibacillus sphaericus OX=1421 GN=nagA PE=2 SV=1
P96166 5.27e-46 50 358 57 367
N-acetylglucosamine-6-phosphate deacetylase OS=Vibrio furnissii OX=29494 GN=manD PE=3 SV=1
A7MBC0 1.86e-44 1 359 12 384
N-acetylglucosamine-6-phosphate deacetylase OS=Bos taurus OX=9913 GN=AMDHD2 PE=2 SV=1
Q6P0U0 6.60e-43 14 359 25 384
N-acetylglucosamine-6-phosphate deacetylase OS=Danio rerio OX=7955 GN=amdhd2 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000073 0.000002 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002169_00350.