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CAZyme Information: MGYG000000240_00729

You are here: Home > Sequence: MGYG000000240_00729

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Amedibacterium intestinale
Lineage Bacteria; Firmicutes; Bacilli; Erysipelotrichales; Erysipelotrichaceae; Amedibacterium; Amedibacterium intestinale
CAZyme ID MGYG000000240_00729
CAZy Family GH129
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
619 MGYG000000240_8|CGC1 72503.1 6.4727
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000240 2625986 Isolate China Asia
Gene Location Start: 31388;  End: 33247  Strand: +

Full Sequence      Download help

MEWNWKNLTF  NFKEDTLQIK  IHTPDTNWIT  QKHRAYLLTD  ERKLYFHDIK  SISHIPYKNG60
IGEGILTHYL  DDGLAFDTII  WSEYRNGTLH  FEWIPIKEDK  NIKEVVWPSP  MEFEAYDSHW120
YSLLNLQQGL  LLPNTWKEEL  TKLPFDGQFA  SSSAYMPWFG  QIKNRNGYMC  ICETYWDCAY180
SVEHPANGPY  TNLFLRWLPS  MGHMCYPRKM  QMHFYQNCDY  NTLCKEYRLY  AEEKGKVTTL240
KEKCAKNPLV  DKLIGSGFVH  MGIKTFVQKD  SSFYDQKDPE  KNNSITSFSK  RAEEILHYKK300
QGIKKLYLHL  DGWAQYGYDN  NHPDILPACE  EAGGWEGLKA  LSDTIKNCNY  MLGLHDQYRD360
YYHRAASYDP  AYSVHTANAK  RPSHASWAGG  HQDYLCSAFA  PLYVKRNYTE  ILAHNIHLEG420
SYLDVFTCNE  PDECIHPYHP  VSRRQCLDNR  LECFSYMQSQ  GILPSSEEVN  EWALSQLVYC480
HYAPYDFQMH  ASSEPRKGIP  VPLFNLVYHD  CVLIPWPMEK  QKGGDDFMLY  ALLNGGGAYL540
RKDAAYPNTD  GMFENEYEKL  SEEECIKRCQ  IVAQLQEKVA  YQKMVHHEFI  HHDPHLQKTV600
FEDGTTITID  LYKQTFKIQ619

Enzyme Prediction      help

EC 3.2.1.49

CAZyme Signature Domains help

Created with Snap3061921231541852162472783093403714024334644955265575888618GH129
Family Start End Evalue family coverage
GH129 8 618 5.8e-186 0.9401294498381877

CDD Domains      download full data without filtering help

Created with Snap306192123154185216247278309340371402433464495526557588273564GH_101_like153610DUF5696303370Glyco_hydro_101
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd14244 GH_101_like 1.62e-71 273 564 2 298
Endo-a-N-acetylgalactosaminidase and related glcyosyl hydrolases. This family contains the enzymatically active domain of cell surface proteins that specifically cleave Gal-beta-1,3-GalNAc-alpha-Ser/Thr (T-antigen, galacto-N-biose), the core 1 type O-linked glycan common to mucin glycoproteins (EC:3.2.1.97). It has been classified as glycosyl hydrolase family 101 in the Cazy resource. Virulence of pathogenic organisms such as the Gram-positive Streptococcus pneumoniae and other commensal human bacteria is largely determined by their ability to degrade host glycoproteins and to metabolize the resultant carbohydrates.
pfam18952 DUF5696 3.05e-10 153 610 120 590
Family of unknown function (DUF5696). This is a family of unknown function with some overlap with clan family members of CL0058.
pfam12905 Glyco_hydro_101 0.010 303 370 47 124
Endo-alpha-N-acetylgalactosaminidase. Virulence of pathogenic organisms such as the Gram-positive Streptococcus pneumoniae is largely determined by the ability to degrade host glycoproteins and to metabolize the resultant carbohydrates. This family is the enzymatic region, EC:3.2.1.97, of the cell surface proteins that specifically cleave Gal-beta-1,3-GalNAc-alpha-Ser/Thr (T-antigen, galacto-N-biose), the core 1 type O-linked glycan common to mucin glycoproteins. This reaction is exemplified by the S. pneumoniae protein Endo-alpha-N-acetylgalactosaminidase, where Asp764 is the catalytic nucleophile-base and Glu796 the catalytic proton donor.

CAZyme Hits      help

Created with Snap3061921231541852162472783093403714024334644955265575881619BBK62377.1|GH1291619BBK22326.1|GH12911619SET52246.1|GH12912619ADL03610.1|GH12912619QRV18247.1|GH129
Hit ID E-Value Query Start Query End Hit Start Hit End
BBK62377.1 0.0 1 619 1 619
BBK22326.1 0.0 1 619 1 619
SET52246.1 9.14e-245 11 619 12 627
ADL03610.1 3.83e-243 12 619 13 627
QRV18247.1 3.83e-243 12 619 13 627

PDB Hits      download full data without filtering help

Created with Snap30619212315418521624727830934037140243346449552655758816185WZN_A16185WZQ_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5WZN_A 5.43e-209 1 618 2 628
Alpha-N-acetylgalactosaminidaseNagBb from Bifidobacterium bifidum - GalNAc complex [Bifidobacterium bifidum],5WZN_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - GalNAc complex [Bifidobacterium bifidum],5WZP_A Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free [Bifidobacterium bifidum],5WZP_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - ligand free [Bifidobacterium bifidum],5WZR_A Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - Gal-NHAc-DNJ complex [Bifidobacterium bifidum],5WZR_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - Gal-NHAc-DNJ complex [Bifidobacterium bifidum]
5WZQ_A 3.02e-203 1 618 2 628
Alpha-N-acetylgalactosaminidaseNagBb from Bifidobacterium bifidum - quadruple mutant [Bifidobacterium bifidum],5WZQ_B Alpha-N-acetylgalactosaminidase NagBb from Bifidobacterium bifidum - quadruple mutant [Bifidobacterium bifidum]

Swiss-Prot Hits      help

has no Swissprot hit.

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000066 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000240_00729.