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CAZyme Information: MGYG000002039_00485
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | UMGS966 sp900761965 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UMGS966; UMGS966 sp900761965 | |||||||||||
| CAZyme ID | MGYG000002039_00485 | |||||||||||
| CAZy Family | CBM48 | |||||||||||
| CAZyme Description | 1,4-alpha-glucan branching enzyme GlgB | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 8067; End: 9962 Strand: - | |||||||||||
Full Sequence Download help
| MAKISKRDSE FLELFHTDIN PRAYQLLGAK KTVRKNGEAG FTFRVWAPNA EGVSVVGDFN | 60 |
| GWDPKANRMK PLGDAGVWEC FVPGLEEGAA YKYCFQAPGG NTLLKMDPYG VRTSAQPQND | 120 |
| SVTCSLDGYH WQDADWMQAR RTAPKGRPIN IYQLHLGSWR RGEGGRLYSY AELAGILPDY | 180 |
| VQEMGYTHIE LMPIMEYGFD GAWGYRTTSY FAPTFRYGDP AGLMQLIDRC HQLGIGVLMD | 240 |
| WNIAHFPKDS HGLIDLDGGS CYEYDDPMKR EHSQWDTRVF DYSRPEVRSF LLSNALFWLE | 300 |
| VYHLDGLRLN NVSSMLYLDY GRESWEWSPN IQGGRENLEA IDFLRRLNET VLQEQPGVLM | 360 |
| IAEEFGQFPG LTLPVMLGGL GFTHCWNVSW TRDMMSYFSL APEYRVYSQD KLTFGTDSAF | 420 |
| GESYILPLSH EEFVYGKRSL MEKLPGLPEQ KLAGVRSFFA FMMAYPGKKM SFMGSEFGQI | 480 |
| DQWDYHTQLQ WELLEDPGHL GTQRCIRELN TVYRKNCPLW EDEANRDSFY WIDSGNLRPD | 540 |
| VVAFVRMDEE GDELIVVANF SDRPVDYRLG LPDERTYTVI FDSNLERFGG TQPEEHRTIE | 600 |
| PIPREFGSFD QYAQLELAPY SVVYLRDDVQ E | 631 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH13 | 179 | 479 | 2.9e-129 | 0.9966777408637874 |
| CBM48 | 27 | 112 | 3.1e-19 | 0.881578947368421 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK12313 | PRK12313 | 0.0 | 12 | 626 | 12 | 626 | 1,4-alpha-glucan branching protein GlgB. |
| PRK05402 | PRK05402 | 0.0 | 12 | 626 | 105 | 722 | 1,4-alpha-glucan branching protein GlgB. |
| PRK12568 | PRK12568 | 0.0 | 8 | 628 | 108 | 729 | glycogen branching enzyme; Provisional |
| COG0296 | GlgB | 0.0 | 14 | 626 | 13 | 627 | 1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism]. |
| cd11322 | AmyAc_Glg_BE | 0.0 | 117 | 515 | 3 | 402 | Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme). The glycogen branching enzyme catalyzes the third step of glycogen biosynthesis by the cleavage of an alpha-(1,4)-glucosidic linkage and the formation a new alpha-(1,6)-branch by subsequent transfer of cleaved oligosaccharide. They are part of a group called branching enzymes which catalyze the formation of alpha-1,6 branch points in either glycogen or starch. This group includes proteins from bacteria, eukaryotes, and archaea. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| CAB1241654.1 | 4.74e-215 | 1 | 626 | 1 | 628 |
| QEY35933.1 | 1.42e-213 | 12 | 626 | 12 | 627 |
| QCN92803.1 | 2.35e-213 | 3 | 626 | 7 | 630 |
| ADU27510.1 | 2.35e-213 | 3 | 626 | 7 | 630 |
| AYF39224.1 | 2.35e-213 | 3 | 626 | 7 | 630 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6JOY_A | 2.26e-177 | 23 | 628 | 20 | 619 | TheX-ray Crystallographic Structure of Branching Enzyme from Rhodothermus obamensis STB05 [Rhodothermus marinus] |
| 5GR0_A | 1.76e-169 | 10 | 591 | 132 | 737 | Crystalstructure of branching enzyme D501A mutant from Cyanothece sp. ATCC 51142 [Crocosphaera subtropica ATCC 51142] |
| 5GQW_A | 1.76e-169 | 10 | 591 | 132 | 737 | Crystalstructure of branching enzyme W610N mutant from Cyanothece sp. ATCC 51142 [Crocosphaera subtropica ATCC 51142],5GQX_A Crystal structure of branching enzyme W610N mutant from Cyanothece sp. ATCC 51142 in complex with maltoheptaose [Crocosphaera subtropica ATCC 51142] |
| 5GR1_A | 1.76e-169 | 10 | 591 | 132 | 737 | Crystalstructure of branching enzyme Y500A/D501A mutant from Cyanothece sp. ATCC 51142 in complex with maltoheptaose [Crocosphaera subtropica ATCC 51142],5GR6_A Crystal structure of branching enzyme Y500A/D501A double mutant from Cyanothece sp. ATCC 51142 [Crocosphaera subtropica ATCC 51142] |
| 5GR2_A | 2.48e-169 | 10 | 591 | 132 | 737 | Crystalstructure of branching enzyme L541A mutant from Cyanothece sp. ATCC 51142 [Crocosphaera subtropica ATCC 51142],5GR4_A Crystal structure of branching enzyme L541A mutant from Cyanothece sp. ATCC 51142 in complex with maltoheptaose [Crocosphaera subtropica ATCC 51142] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q3JCN0 | 8.04e-191 | 12 | 600 | 116 | 705 | 1,4-alpha-glucan branching enzyme GlgB OS=Nitrosococcus oceani (strain ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107) OX=323261 GN=glgB PE=3 SV=1 |
| O66936 | 7.11e-189 | 1 | 628 | 1 | 629 | 1,4-alpha-glucan branching enzyme GlgB OS=Aquifex aeolicus (strain VF5) OX=224324 GN=glgB PE=3 SV=1 |
| B8CVY1 | 8.10e-188 | 14 | 626 | 13 | 626 | 1,4-alpha-glucan branching enzyme GlgB OS=Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) OX=373903 GN=glgB PE=3 SV=1 |
| Q2RR72 | 2.00e-186 | 16 | 628 | 123 | 733 | 1,4-alpha-glucan branching enzyme GlgB OS=Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) OX=269796 GN=glgB PE=3 SV=1 |
| Q0AGJ0 | 1.59e-183 | 12 | 625 | 116 | 731 | 1,4-alpha-glucan branching enzyme GlgB OS=Nitrosomonas eutropha (strain DSM 101675 / C91 / Nm57) OX=335283 GN=glgB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000086 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |