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CAZyme Information: MGYG000004469_00452

You are here: Home > Sequence: MGYG000004469_00452

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Alistipes_A sp900545315
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes_A; Alistipes_A sp900545315
CAZyme ID MGYG000004469_00452
CAZy Family GH13
CAZyme Description 1,4-alpha-glucan branching enzyme GlgB
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
678 MGYG000004469_3|CGC2 78467.67 4.9833
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000004469 2457179 MAG Israel Asia
Gene Location Start: 128712;  End: 130748  Strand: -

Full Sequence      Download help

MQLPKHLPIV  EQDDWLKPVE  EAMMGRYAYF  RRRLEDIERA  AGSIVDYANG  YLYFGFQYDP60
IRRGWWFREW  LPGAFDVYLF  GDFNDWQRTE  LRLEKGDNGV  WSIFLPDERY  AGRLVHGSHV120
KMLVHGLNGW  LERIPAYIRR  VVQDEQSKDF  TGQLWAPPVP  FDWEGDCFDI  ASLGTLYIYE180
CHVGMAQEKE  GVGTYTEFTE  NILPRIKQDG  YNVVQLMAVA  EHPYYGSFGY  HVSNFFAPSS240
RFGTPEELKA  LIKRAHELGL  AVVMDLVQAH  YVKNINEGLN  ELDGTDHLYS  PPGPAGDQPY300
WDSKLFDYAK  PEVEHFLLSN  VKYWLDEFHF  DGFRFDGVTS  MIYTHHGYTE  FDCREKYFDD360
VNGDALAYLT  LANKLVHDFR  PSAVTIAEDV  SGMPGMCAPV  EDGGVGFDYR  LGMAVPDFWI420
RLLKEVPDEE  WNIWEMWHMM  VDRLGSVKTV  AYCESHDQAL  VGDKTIAFRL  MDKQMYTDMN480
RAAENLIIDR  GMALHKMIRL  FTISLAGEAY  LNFMGNEFGH  PEWIDFPREG  NGWSYAHARR540
QWSLSTNGFL  RYSFLGAFDR  AMLELMQRYD  VLASGFAYNH  QMDEENKTIV  FSHRGDLVFI600
FNWHPQRSIP  DYEATVPAPG  KYRIELSSDE  KRFGGYGRID  ETLEAFSTPR  KAEDGSVTHF660
IKVYNLSRAA  LVLKKVDE678

Enzyme Prediction      help

EC 2.4.1.18

CAZyme Signature Domains help

Created with Snap3367101135169203237271305339372406440474508542576610644227516GH13
Family Start End Evalue family coverage
GH13 227 516 4.8e-137 0.9965870307167235

CDD Domains      download full data without filtering help

Created with Snap33671011351692032372713053393724064404745085425766106446678PLN02447176560AmyAc_bac_euk_BE108655PLN02960108674PLN0324451674GlgB
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PLN02447 PLN02447 0.0 6 678 59 733
1,4-alpha-glucan-branching enzyme
cd11321 AmyAc_bac_euk_BE 0.0 176 560 18 406
Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes. Branching enzymes (BEs) catalyze the formation of alpha-1,6 branch points in either glycogen or starch by cleavage of the alpha-1,4 glucosidic linkage yielding a non-reducing end oligosaccharide chain, and subsequent attachment to the alpha-1,6 position. By increasing the number of non-reducing ends, glycogen is more reactive to synthesis and digestion as well as being more soluble. This group includes bacterial and eukaryotic proteins. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.
PLN02960 PLN02960 7.58e-169 108 655 328 872
alpha-amylase
PLN03244 PLN03244 1.29e-134 108 674 333 865
alpha-amylase; Provisional
COG0296 GlgB 1.52e-103 51 674 23 627
1,4-alpha-glucan branching enzyme [Carbohydrate transport and metabolism].

CAZyme Hits      help

Created with Snap33671011351692032372713053393724064404745085425766106442678BCG53012.1|CBM48|GH13_87677QGA22623.1|CBM48|GH13_87672BBL05793.1|CBM48|GH13_85672CBK62836.1|CBM48|GH13_85672BBL02139.1|CBM48|GH13_8
Hit ID E-Value Query Start Query End Hit Start Hit End
BCG53012.1 0.0 2 678 4 680
QGA22623.1 0.0 7 677 9 679
BBL05793.1 0.0 7 672 8 673
CBK62836.1 0.0 5 672 6 673
BBL02139.1 0.0 5 672 6 672

PDB Hits      download full data without filtering help

Created with Snap336710113516920323727130533937240644047450854257661064436774BZY_A66783AMK_A66783VU2_A166775CLT_A66783AML_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
4BZY_A 6.33e-205 3 677 25 699
Crystalstructure of human glycogen branching enzyme (GBE1) [Homo sapiens],4BZY_B Crystal structure of human glycogen branching enzyme (GBE1) [Homo sapiens],4BZY_C Crystal structure of human glycogen branching enzyme (GBE1) [Homo sapiens]
3AMK_A 1.02e-203 6 678 10 695
Structureof the Starch Branching Enzyme I (BEI) from Oryza sativa L [Oryza sativa Japonica Group]
3VU2_A 2.89e-203 6 678 10 695
Structureof the Starch Branching Enzyme I (BEI) complexed with maltopentaose from Oryza sativa L [Oryza sativa Japonica Group],3VU2_B Structure of the Starch Branching Enzyme I (BEI) complexed with maltopentaose from Oryza sativa L [Oryza sativa Japonica Group]
5CLT_A 3.77e-203 16 677 6 667
Crystalstructure of human glycogen branching enzyme (GBE1) in complex with acarbose [Homo sapiens],5CLT_B Crystal structure of human glycogen branching enzyme (GBE1) in complex with acarbose [Homo sapiens],5CLT_C Crystal structure of human glycogen branching enzyme (GBE1) in complex with acarbose [Homo sapiens],5CLW_A Crystal structure of human glycogen branching enzyme (GBE1) in complex with maltoheptaose [Homo sapiens],5CLW_B Crystal structure of human glycogen branching enzyme (GBE1) in complex with maltoheptaose [Homo sapiens],5CLW_C Crystal structure of human glycogen branching enzyme (GBE1) in complex with maltoheptaose [Homo sapiens]
3AML_A 5.70e-203 6 678 10 695
Structureof the Starch Branching Enzyme I (BEI) from Oryza sativa L [Oryza sativa Japonica Group]

Swiss-Prot Hits      download full data without filtering help

Created with Snap33671011351692032372713053393724064404745085425766106449677sp|Q555Q9|GLGB_DICDI7678sp|Q6CCT1|GLGB_YARLI9673sp|P0CN83|GLGB_CRYNB9673sp|P0CN82|GLGB_CRYNJ9673sp|Q8NKE1|GLGB_RHIID
Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q555Q9 6.27e-225 9 677 13 678
1,4-alpha-glucan-branching enzyme OS=Dictyostelium discoideum OX=44689 GN=glgB PE=3 SV=1
Q6CCT1 4.82e-212 7 678 3 687
1,4-alpha-glucan-branching enzyme OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=GLC3 PE=3 SV=1
P0CN83 4.07e-211 9 673 12 680
1,4-alpha-glucan-branching enzyme OS=Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) OX=283643 GN=GLC3 PE=3 SV=1
P0CN82 4.07e-211 9 673 12 680
1,4-alpha-glucan-branching enzyme OS=Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) OX=214684 GN=GLC3 PE=3 SV=1
Q8NKE1 1.36e-209 9 673 16 680
1,4-alpha-glucan-branching enzyme OS=Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) OX=747089 GN=GLC3 PE=2 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000074 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000004469_00452.