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CAZyme Information: MGYG000000013_00524

You are here: Home > Sequence: MGYG000000013_00524

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides sp902362375
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides sp902362375
CAZyme ID MGYG000000013_00524
CAZy Family GH2
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
987 MGYG000000013_2|CGC3 112916.08 7.1653
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000013 6368149 Isolate United Kingdom Europe
Gene Location Start: 54533;  End: 57496  Strand: -

Full Sequence      Download help

MKHQLYLFVF  LLITLSIINS  QAAERKKYNF  NSEWKLQIGE  FPKAKDTKFD  DSEWKQVTLP60
HAFNEDEAFK  LSIEQLTDTV  VWYRKSFRIP  ELKSNQKVFI  EFEGVRQRGD  FYLNGHNLGR120
HENGVMAVGF  DLTPYMKEGE  NVIAVRTDNN  WMYREEGTNS  KFQWNDRNFN  ANYGGIPKNV180
FLYVTDNVYQ  TLPLYSNLKT  TGVYVYAKDF  DIKGHKATIH  AESEVRNDSK  SPRQFSYQVT240
VLDADGKRLK  TFQGDKVTLK  AGETKTVKAS  AIINNLHFWS  WGYGYLYTVK  TALKDDSNQI300
FDEVSTRTGF  RKTRFVEGKI  ELNDRVIQMK  GYAQRTSNEW  PAVGLSVPAW  LSDFSNGLMV360
KGNANLVRWM  HVTPWKQDVE  SCDRVGLIQA  MPAGDAEKDR  EGRQWEQRVE  LMRDAIIYNR420
NNPSILFYEC  GNKAISREHM  IEMKAVRDKY  DPFGGRAIGS  REMLDIREAE  YGGEMLYINR480
SEHHPMWATE  YCRDEGLRKY  WDEYSYPFHK  EGDGPLYKGK  PATDYNRNQD  EFAITMIARW540
YDYWRERPGT  GNRVSSGGTK  IIFSDTNTHY  RGAENYRRSG  VTDAMRIEKD  AFYAHQVMWN600
GWVDTEEDQT  YIIGHWNYPE  NTVKPIHVVS  TGEEVELFLN  GKSLGKGKRQ  YNFLFTFDNI660
TFKPGKLEAV  SYNQAGKEIS  RYAIHTAGEP  AKLKLTAIQN  PEGFHGDGAD  MALIQVEVVD720
KDGKRCPLDN  RTVQFTLNGQ  AEWRGGIAQG  ENNHILDTKL  PVECGINRAL  IRSTTTAGKV780
TLTAQAKGLL  AATLTLETVP  VKVTEGLSTY  LPQETLKGQL  DRGETPSTPS  YQDSKKGVRI840
VSAKAGSNNS  DAEKSYDDIE  LTEWKNDGKL  STAWITYTLE  REAEIDDICI  KLQGWRSRSY900
PLEVYAGNIL  IWNGNTDKSL  GYIHLNVEKP  VRANTITIRL  KGNTSDKDAF  GQIIEVEAKA960
ANKMEQEKSS  SKNQLRIIEV  EFLETIK987

Enzyme Prediction      help

EC 3.2.1.31

CAZyme Signature Domains help

Created with Snap499814819724629634539444449354259264169074078983888893719772GH2
Family Start End Evalue family coverage
GH2 19 772 3.6e-68 0.8204787234042553

CDD Domains      download full data without filtering help

Created with Snap499814819724629634539444449354259264169074078983888893724513LacZ81453PRK101501452ebgA31185Glyco_hydro_2_N693795Glyco_hydro2_C5
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 8.17e-30 24 513 9 495
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150 PRK10150 1.25e-23 81 453 67 432
beta-D-glucuronidase; Provisional
PRK10340 ebgA 8.56e-21 1 452 15 468
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02837 Glyco_hydro_2_N 5.00e-18 31 185 5 168
Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.
pfam18565 Glyco_hydro2_C5 1.27e-17 693 795 1 103
Glycoside hydrolase family 2 C-terminal domain 5. Domain 5 is found in dimeric beta-D-galactosidase from Paracoccus sp. 32d, which contributes to stabilization of the functional dimer. It is suggested that the location of this domain 5, may be one of the factors responsible for the creation of a functional dimer and cold-adaptation of this enzyme.

CAZyme Hits      help

Created with Snap49981481972462963453944444935425926416907407898388889371987QNL41159.1|GH21987ALJ49030.1|GH21987QRQ55837.1|GH21987SCV08447.1|GH21987QUT27395.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
QNL41159.1 0.0 1 987 1 987
ALJ49030.1 0.0 1 987 1 987
QRQ55837.1 0.0 1 987 1 987
SCV08447.1 0.0 1 987 1 987
QUT27395.1 0.0 1 987 1 987

PDB Hits      download full data without filtering help

Created with Snap4998148197246296345394444493542592641690740789838888937228136HPD_A267987CWD_A267894YPJ_A297965T98_A207864CUC_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
6HPD_A 2.80e-154 22 813 32 819
Thestructure of a beta-glucuronidase from glycoside hydrolase family 2 [Formosa agariphila KMM 3901]
7CWD_A 1.45e-63 26 798 2 801
ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans]
4YPJ_A 4.93e-57 26 789 8 798
ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]
5T98_A 4.53e-56 29 796 29 818
Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis]
4CUC_A 7.70e-48 20 786 8 832
Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA. [Streptococcus pneumoniae TIGR4]

Swiss-Prot Hits      download full data without filtering help

Created with Snap499814819724629634539444449354259264169074078983888893722813sp|T2KN75|PLH17_FORAG11742sp|T2KM09|PLH16_FORAG19794sp|A7LXS9|BGH2A_BACO125726sp|T2KPJ7|PLH8_FORAG25786sp|P77989|BGAL_THEP3
Hit ID E-Value Query Start Query End Hit Start Hit End Description
T2KN75 1.22e-153 22 813 23 810
Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1
T2KM09 1.34e-47 11 742 32 761
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
A7LXS9 4.26e-46 19 794 36 844
Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KPJ7 6.91e-38 25 726 51 757
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
P77989 1.02e-36 25 786 3 725
Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000207 0.999172 0.000156 0.000158 0.000140 0.000135

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000013_00524.