logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000022_00313

You are here: Home > Sequence: MGYG000000022_00313

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Faecalibacterium prausnitzii_C
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Faecalibacterium; Faecalibacterium prausnitzii_C
CAZyme ID MGYG000000022_00313
CAZy Family GH2
CAZyme Description Beta-glucuronidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
608 MGYG000000022_1|CGC5 69291.37 6.6514
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000022 3052239 Isolate United Kingdom Europe
Gene Location Start: 336430;  End: 338256  Strand: -

Full Sequence      Download help

MNRSLLYPRA  TTTRRLIGLD  GMWRFSFDPE  SKGVEAGWAL  DLPSSLSMPV  PASFCDLFTD60
KASREYCGDF  WYETSFFVPA  EWSGWDIVLR  FGSVTHRARV  FVNGVEVAQH  EGGFLPFDAT120
VTNIVRYNQF  NKLSVLANNE  LSETMLPAGT  TCTLADGRKI  AAPYFDFYNY  AGIHRPVWLM180
ALPKERVLDY  STRYRLTETG  AEIDYTVSTN  GPHPVTVELY  DGTTRVAESS  GTTGTLVVKN240
ARLWNVHAAY  LYDLVIRIHE  GSAVVDEYLD  RIGIRTFEIR  HGRFLLNGSP  VYLRGFGRHE300
DADIRGRGLD  LPTVKRDFEL  MKWIGANCFR  TSHYPYAEEI  YQMADEEGFL  IIDEVPAVGF360
MQSTANFLAA  NQGNGRQQGF  FEKETTPALL  KNHKAALTDM  IDRDKNHPSV  IAWSLLNEPQ420
CTSAGTEEYF  KPLFELARRL  DPQKRPRTYT  VLMTSLPDTS  KGQRFADFVS  LNRYYGWYVL480
GGAGLADAEA  AFHHEMDGWA  KVLHGRPLIF  TEYGTDNLSG  AHKLPSVMWS  AEYQNEYLEM540
THAVFDHYDF  VQGELVWNFA  DFQTTEGILR  VDGNKKGIFT  RQRQPKDAAY  LFRKRWTTLP600
VDFKKRKK608

Enzyme Prediction      help

EC 3.2.1.31

CAZyme Signature Domains help

Created with Snap30609112115218221224327330433436439542545648651654757710595GH2
Family Start End Evalue family coverage
GH2 10 595 4.3e-109 0.6143617021276596

CDD Domains      download full data without filtering help

Created with Snap3060911211521822122432733043343643954254564865165475775607PRK1015011597LacZ277597Glyco_hydro_2_C72574ebgA19418lacZ
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK10150 PRK10150 0.0 5 607 1 603
beta-D-glucuronidase; Provisional
COG3250 LacZ 6.91e-111 11 597 7 596
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam02836 Glyco_hydro_2_C 1.39e-81 277 597 1 298
Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10340 ebgA 1.99e-36 72 574 113 556
cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525 lacZ 2.25e-36 19 418 55 462
beta-galactosidase.

CAZyme Hits      help

Created with Snap3060911211521822122432733043343643954254564865165475771608EEU97254.1|GH2|3.2.1.311608ATP00638.1|GH2|3.2.1.311608QIA43639.1|GH21608ATL90844.1|GH24604QJU16299.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
EEU97254.1 0.0 1 608 1 608
ATP00638.1 0.0 1 608 1 608
QIA43639.1 0.0 1 608 1 608
ATL90844.1 0.0 1 608 1 608
QJU16299.1 2.65e-266 4 604 5 604

PDB Hits      download full data without filtering help

Created with Snap30609112115218221224327330433436439542545648651654757716086ED2_A26047KGY_A45966JZ1_A45965Z18_A45966EC6_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
6ED2_A 0.0 1 608 24 631
ChainA, Glycosyl hydrolase family 2, TIM barrel domain protein [Faecalibacterium duncaniae]
7KGY_A 0.0 2 604 3 605
ChainA, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_B Chain B, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_C Chain C, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_D Chain D, Beta-glucuronidase [Faecalibacterium prausnitzii]
6JZ1_A 1.16e-248 4 596 5 596
Apostructure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ1_B Apo structure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ5_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ5_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ6_A b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ6_B b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_A b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_B b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ8_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus],6JZ8_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus]
5Z18_A 2.72e-248 4 596 29 620
Thecrystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_B The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_C The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_D The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_E The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_F The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z19_A The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_B The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_C The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_D The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_E The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_F The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],6JZ2_A b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution [[Ruminococcus] gnavus],6JZ2_B b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution [[Ruminococcus] gnavus],6JZ3_A b-glucuronidase from Ruminococcus gnavus in complex with uronic deoxynojirimycin [[Ruminococcus] gnavus],6JZ3_B b-glucuronidase from Ruminococcus gnavus in complex with uronic deoxynojirimycin [[Ruminococcus] gnavus],6JZ4_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro-d-lactam [[Ruminococcus] gnavus],6JZ4_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro-d-lactam [[Ruminococcus] gnavus]
6EC6_A 2.14e-247 4 596 28 619
Ruminococcusgnavus Beta-glucuronidase [[Ruminococcus] gnavus],6EC6_B Ruminococcus gnavus Beta-glucuronidase [[Ruminococcus] gnavus]

Swiss-Prot Hits      download full data without filtering help

Created with Snap3060911211521822122432733043343643954254564865165475775597sp|P05804|BGLR_ECOLI5599sp|O18835|BGLR_CANLF5599sp|O97524|BGLR_FELCA5596sp|O77695|BGLR_CHLAE5596sp|P12265|BGLR_MOUSE
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P05804 1.97e-167 5 597 1 589
Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2
O18835 1.90e-136 5 599 27 628
Beta-glucuronidase OS=Canis lupus familiaris OX=9615 GN=GUSB PE=1 SV=1
O97524 6.62e-134 5 599 27 628
Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1
O77695 4.78e-133 5 596 24 623
Beta-glucuronidase (Fragment) OS=Chlorocebus aethiops OX=9534 GN=GUSB PE=2 SV=1
P12265 3.77e-132 5 596 27 622
Beta-glucuronidase OS=Mus musculus OX=10090 GN=Gusb PE=1 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000080 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000022_00313.