logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000499_00073

You are here: Home > Sequence: MGYG000000499_00073

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species HGM11416 sp900768525
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; Borkfalkiaceae; HGM11416; HGM11416 sp900768525
CAZyme ID MGYG000000499_00073
CAZy Family GH2
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
745 MGYG000000499_2|CGC1 86183.79 5.1958
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000499 2647539 MAG Fiji Oceania
Gene Location Start: 32250;  End: 34487  Strand: +

Full Sequence      Download help

MNKISLNGNY  KLYITDGKNF  DFDEVSFNGL  GEPVDATVPG  NVELDLMRAN  LLPDLYFADN60
IKKAEYLESK  DFVYVKDFEF  SFNDNCHREL  VFCGVDTIAE  YYLNGVKIGK  SENAFVEYRF120
SVDNVLKNGN  NRLVVHIFSS  VNHAKKYEYT  PLNIGIYDGC  YESLNIRKPA  SSFGWDILPR180
AVSAGIFRDV  YIREYSAVEI  TNVYIATNRL  VDNLAILTVS  VNARIADEFL  GKLTLKITGK240
CKNSEFVKIC  PFTFTAKTVF  PYVENPVLWY  PCGYGSPDLY  DVTVELVADG  KVMAQKSIKF300
GIRSVEVRYT  EEIGENGDFR  ILVNNKLIKV  KGVNHTPIDV  YHSKDKEKYA  DIVDGIKGMN360
CNFVRIWGGG  VYEDDEFYSL  CDENGIMVWH  DFMLACHMYP  QTQEFLNKIS  FECKNVVERL420
RNHTSIIAWC  GSNETDWMYT  CIGLNPNDDK  ITRVVMKDVL  SAVDPFRPFF  PTTPYFSDEF480
IKKQGGVFYV  DLAEITERRR  PLPEEHFWWH  RNDFLKFTDQ  NHKFIMEIGF  GGCNSLEKLN540
KYLPNGWNFK  DDKYWSCHSY  PTEDSRTVGL  DYLFYGVENN  DDDLVSASRA  YQAEAYKYIV600
ERSRIRPYFN  GICLWNYRDG  FPIFSSAFVD  YDGDKRPSYF  AVKNSYEPVQ  CIMKYEKGKV660
EVYIVNDTSF  TGKVGLKLSL  ASGTKEKEIE  IKANEILLFD  TLNCDENRLI  TSELSVCDKK720
INNYLYTYDE  KIDYKRYKEL  LTRKD745

Enzyme Prediction      help

No EC number prediction in MGYG000000499_00073.

CAZyme Signature Domains help

Created with Snap37741111491862232602983353724094474845215585966336707072714GH2
Family Start End Evalue family coverage
GH2 2 714 2.7e-86 0.6941489361702128

CDD Domains      download full data without filtering help

Created with Snap37741111491862232602983353724094474845215585966336707073668LacZ80437ebgA198303Glyco_hydro_2263332PRK10150321468Glyco_hydro_2_C
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 7.80e-57 3 668 12 653
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 4.26e-18 80 437 117 452
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam00703 Glyco_hydro_2 1.13e-11 198 303 1 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10150 PRK10150 2.97e-05 263 332 239 296
beta-D-glucuronidase; Provisional
pfam02836 Glyco_hydro_2_C 0.005 321 468 8 157
Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.

CAZyme Hits      help

Created with Snap37741111491862232602983353724094474845215585966336707074743QDH53813.1|GH24743QQR15691.1|GH24743ANU59404.1|GH24743QRM99259.1|GH24743QNL40264.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
QDH53813.1 3.26e-116 4 743 27 793
QQR15691.1 8.97e-116 4 743 27 793
ANU59404.1 8.97e-116 4 743 27 793
QRM99259.1 1.26e-115 4 743 27 793
QNL40264.1 1.76e-115 4 743 27 793

PDB Hits      download full data without filtering help

Created with Snap3774111149186223260298335372409447484521558596633670707367065N6U_A246672VJX_A246672JE8_A246677OP6_A246672WBK_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5N6U_A 3.27e-97 36 706 46 719
Crystalstructure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_B Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_C Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_D Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12]
2VJX_A 6.43e-77 24 667 16 672
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A 6.64e-77 24 667 18 674
Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A 6.74e-77 24 667 18 674
ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A 1.72e-76 24 667 16 672
Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Created with Snap377411114918622326029833537240944748452155859663367070739649sp|I2C092|MANBB_THETO28667sp|Q8K2I4|MANBA_MOUSE36667sp|Q4FZV0|MANBA_RAT4667sp|Q95327|MANBA_CAPHI4663sp|Q29444|MANBA_BOVIN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
I2C092 2.19e-56 39 649 32 660
Beta-mannosidase B OS=Thermothelomyces thermophilus OX=78579 GN=man9 PE=1 SV=1
Q8K2I4 5.44e-53 28 667 33 709
Beta-mannosidase OS=Mus musculus OX=10090 GN=Manba PE=1 SV=1
Q4FZV0 5.51e-53 36 667 42 709
Beta-mannosidase OS=Rattus norvegicus OX=10116 GN=Manba PE=2 SV=1
Q95327 4.50e-52 4 667 23 709
Beta-mannosidase OS=Capra hircus OX=9925 GN=MANBA PE=1 SV=1
Q29444 5.00e-51 4 663 23 705
Beta-mannosidase OS=Bos taurus OX=9913 GN=MANBA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000066 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000499_00073.