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CAZyme Information: MGYG000002149_00105
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Blautia sp003287895 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia; Blautia sp003287895 | |||||||||||
| CAZyme ID | MGYG000002149_00105 | |||||||||||
| CAZy Family | GH2 | |||||||||||
| CAZyme Description | Beta-glucuronidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 94053; End: 95834 Strand: - | |||||||||||
Full Sequence Download help
| MLYPRMSSGR MVFDLNGIWD FKLLEKTGTE REHAGLHLTG GRAMPVPSSY NDIYPEKDFA | 60 |
| DHVGEMVYQR TFTVTESMKK GRLVLRFGSV THQAEVYLNG KRLGEHKGGF LPFSFEIAEQ | 120 |
| AVVGENLLTV FVNNIVDYST LPCGRMVTEE FPGLEPRTVN LPNFDFYNYT GIMRPVWLYT | 180 |
| TPVVYIRDIT VSGKKDGSFA WNIEVSGEEE ENAEVQVRVL EMNGVCVYEG SGKSGSGKIE | 240 |
| NVKLWSVKEP NLYQLEVRLK TGEAIEDAYT ETFGFREISI ENCRILLNGE PVYLKGFGKH | 300 |
| EEGGTRGRGT DLALMTKDLG LLKWIHANSF RTSHYPNSEE MMQLCDKMGI LVIDEAPAVG | 360 |
| LNTGFTATGL LGGNPKGTWQ TLETAQHHRE VMEDLVARDK NHPCVIAWSV ANEPASQEEG | 420 |
| AKEYFEPLVR LTKEKDVQHR PVTIVTYEGS APDTCKVAEL CDFLMLNRYR GWYDTEGNLR | 480 |
| GAAAKLKAEL EGFHKRCPDK PMMLGEYGAD TIAGLHDINA RLFTEEYQTA FMKAYGEVFD | 540 |
| SLPYITGEHV WVFADFATAE NIKRVDGNKK GIFTRERRPK QAAYFLKERW ENL | 593 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH2 | 10 | 591 | 1.2e-109 | 0.6117021276595744 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK10150 | PRK10150 | 0.0 | 1 | 593 | 1 | 595 | beta-D-glucuronidase; Provisional |
| COG3250 | LacZ | 1.22e-110 | 9 | 592 | 9 | 597 | Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]. |
| pfam02836 | Glyco_hydro_2_C | 3.81e-81 | 278 | 592 | 1 | 299 | Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. |
| PRK10340 | ebgA | 3.18e-52 | 67 | 449 | 112 | 476 | cryptic beta-D-galactosidase subunit alpha; Reviewed |
| PRK09525 | lacZ | 2.51e-41 | 15 | 454 | 55 | 494 | beta-galactosidase. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AWY98908.1 | 0.0 | 1 | 593 | 1 | 593 |
| QOV20331.1 | 0.0 | 1 | 593 | 1 | 591 |
| AWS24743.1 | 3.58e-209 | 1 | 593 | 1 | 592 |
| ASY50247.1 | 3.58e-209 | 1 | 593 | 1 | 592 |
| AQM59682.1 | 3.71e-209 | 1 | 593 | 1 | 593 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4JKM_A | 5.85e-210 | 1 | 593 | 4 | 595 | CrystalStructure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],4JKM_B Crystal Structure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],6CXS_A Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13],6CXS_B Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13] |
| 6BO6_A | 3.37e-188 | 1 | 593 | 1 | 603 | Eubacteriumeligens beta-glucuronidase bound to UNC4917 glucuronic acid conjugate [[Eubacterium] eligens ATCC 27750] |
| 6BJQ_A | 7.22e-188 | 1 | 593 | 25 | 627 | ChainA, Glycoside Hydrolase Family 2 candidate b-glucuronidase [[Eubacterium] eligens ATCC 27750] |
| 6BJW_A | 7.46e-188 | 1 | 593 | 25 | 627 | ChainA, Glycoside Hydrolase Family 2 candidate b-glucuronidase [[Eubacterium] eligens ATCC 27750] |
| 6D4O_A | 3.00e-187 | 1 | 590 | 4 | 603 | Eubacteriumeligens beta-glucuronidase bound to an amoxapine-glucuronide conjugate [Lachnospira eligens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P05804 | 3.52e-141 | 1 | 593 | 1 | 591 | Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2 |
| O97524 | 2.90e-134 | 1 | 593 | 27 | 628 | Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1 |
| P06760 | 3.30e-132 | 1 | 590 | 27 | 622 | Beta-glucuronidase OS=Rattus norvegicus OX=10116 GN=Gusb PE=1 SV=1 |
| O18835 | 2.84e-131 | 1 | 593 | 27 | 628 | Beta-glucuronidase OS=Canis lupus familiaris OX=9615 GN=GUSB PE=1 SV=1 |
| P12265 | 2.05e-130 | 1 | 590 | 27 | 622 | Beta-glucuronidase OS=Mus musculus OX=10090 GN=Gusb PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000054 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |