logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000003012_00122

You are here: Home > Sequence: MGYG000003012_00122

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Blautia_A sp900540785
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Blautia_A; Blautia_A sp900540785
CAZyme ID MGYG000003012_00122
CAZy Family GH2
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
585 MGYG000003012_1|CGC4 68174.14 5.2847
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003012 3168635 MAG United States North America
Gene Location Start: 130896;  End: 132653  Strand: -

Full Sequence      Download help

MYRSEYPRPE  FKREEWMSLN  GQWDFCFPGE  EMRRIEVPFV  FQSEMSGIHE  NRMCDFVTYK60
RRFCVPDKWK  GKRVRIHFGA  VDYACSVFIN  EKKVGSHQGG  NTPFSFDITE  ELTWNEEEIC120
VQVWDPCRDE  TIPRGKQFWK  KDPDSIWYTR  STGIWQSVFI  EPVSEVHFSY  IRFTPDIDRG180
TVEVKFKAAG  LKEKIGGCHA  EFAITFKERE  VFRGGMELLE  DYGRMEISLF  DRHIFRTMNH240
DGGWCWSPES  PNLFDVKAVL  TKEGETLDQV  SAYFGMRKIE  QKNGMVYLNN  RPYYQKLILD300
QGYWPGSLMT  AQDEQDFVKD  IEMAKAMGFN  GCRKHQKAED  PVFLYHADRI  GFLVWSEISA360
CASYSLEASQ  RTVTEWGEAI  QRDYNHPCIV  AWVVLNESWG  VPNICFDKRQ  QAHSLALYYN420
AKSMDTTRLV  ISNDGWEITK  TDICAIHNYA  HGEQSEPVKQ  EIFRRSLSTK  EDILKAQPAG480
RQIYADGFCH  QGEPVLLTEF  GGLAYAKDRE  KGWGYTTIEN  EEEFLEVYGR  ILKDIADSEI540
LFGFCYTQLC  DVEQEVNGLL  TYDRKYKIAP  EKIKAINDSV  RKDYL585

Enzyme Prediction      help

No EC number prediction in MGYG000003012_00122.

CAZyme Signature Domains help

Created with Snap29588711714617520423426329232135138040943846849752655511451GH2
Family Start End Evalue family coverage
GH2 11 451 4e-96 0.5093085106382979

CDD Domains      download full data without filtering help

Created with Snap2958871171461752042342632923213513804094384684975265551430LacZ6397PRK1015016430ebgA18430lacZ18160Glyco_hydro_2_N
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 4.96e-37 1 430 1 429
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150 PRK10150 1.16e-27 6 397 3 417
beta-D-glucuronidase; Provisional
PRK10340 ebgA 3.57e-25 16 430 41 472
cryptic beta-D-galactosidase subunit alpha; Reviewed
PRK09525 lacZ 4.12e-22 18 430 54 485
beta-galactosidase.
pfam02837 Glyco_hydro_2_N 5.37e-14 18 160 3 165
Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.

CAZyme Hits      help

Created with Snap2958871171461752042342632923213513804094384684975265553577AGA57247.1|GH21585SQI62769.1|GH21578AQU76856.1|GH22578QDM46707.1|GH22578QNF29847.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
AGA57247.1 2.57e-259 3 577 4 589
SQI62769.1 8.19e-258 1 585 1 596
AQU76856.1 4.22e-250 1 578 1 589
QDM46707.1 1.27e-244 2 578 3 590
QNF29847.1 1.00e-243 2 578 3 590

PDB Hits      download full data without filtering help

Created with Snap29588711714617520423426329232135138040943846849752655555807SF2_A184326D8K_A173974JKM_A143975UJ6_A143976D50_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
7SF2_A 1.83e-87 5 580 28 582
ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_E Chain E, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_F Chain F, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
6D8K_A 6.04e-23 18 432 37 442
Bacteroidesmultiple species beta-glucuronidase [Bacteroides ovatus],6D8K_B Bacteroides multiple species beta-glucuronidase [Bacteroides ovatus],6D8K_C Bacteroides multiple species beta-glucuronidase [Bacteroides ovatus],6D8K_D Bacteroides multiple species beta-glucuronidase [Bacteroides ovatus]
4JKM_A 1.09e-22 17 397 16 415
CrystalStructure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],4JKM_B Crystal Structure of Clostridium perfringens beta-glucuronidase [Clostridium perfringens str. 13],6CXS_A Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13],6CXS_B Crystal Structure of Clostridium perfringens beta-glucuronidase bound with a novel, potent inhibitor 4-(8-(piperazin-1-yl)-1,2,3,4-tetrahydro-[1,2,3]triazino[4',5':4,5]thieno[2,3-c]isoquinolin-5-yl)morpholine [Clostridium perfringens str. 13]
5UJ6_A 5.07e-21 14 397 32 418
CrystalStructure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],5UJ6_B Crystal Structure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],6NZG_A Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis],6NZG_B Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis]
6D50_A 5.11e-21 14 397 40 426
Bacteroidesuniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii],6D50_B Bacteroides uniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii]

Swiss-Prot Hits      download full data without filtering help

Created with Snap29588711714617520423426329232135138040943846849752655518415sp|P77989|BGAL_THEP359403sp|T2KPJ7|PLH8_FORAG9430sp|O52847|BGAL_PRIM32541sp|Q03WL0|BGAL_LEUMM35533sp|P26257|BGAL_THETU
Hit ID E-Value Query Start Query End Hit Start Hit End Description
P77989 5.23e-29 18 415 18 406
Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
T2KPJ7 7.33e-24 59 403 107 436
Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
O52847 4.79e-23 9 430 83 504
Beta-galactosidase OS=Priestia megaterium (strain DSM 319 / IMG 1521) OX=592022 GN=bgaM PE=3 SV=1
Q03WL0 5.75e-21 2 541 32 571
Beta-galactosidase OS=Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / DSM 20343 / BCRC 11652 / CCM 1803 / JCM 6124 / NCDO 523 / NBRC 100496 / NCIMB 8023 / NCTC 12954 / NRRL B-1118 / 37Y) OX=203120 GN=lacZ PE=3 SV=1
P26257 4.05e-20 35 533 40 488
Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000034 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003012_00122.