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CAZyme Information: MGYG000003203_00345

You are here: Home > Sequence: MGYG000003203_00345

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Butyricimonas sp900759925
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Marinifilaceae; Butyricimonas; Butyricimonas sp900759925
CAZyme ID MGYG000003203_00345
CAZy Family GH2
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
859 98748.03 5.5279
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003203 5334161 MAG United States North America
Gene Location Start: 4057;  End: 6636  Strand: -

Full Sequence      Download help

MSKILWFAFF  CCSIGGLLGC  SSEKEIRTEI  ASGWQFRQRD  SGEWFPATVP  GTVHTDLMAN60
GKIEDPFYRL  NELGMQWIDK  KDWEYKTVFP  VDGDLIEKKN  QRLTFYGLDT  YADVFLNEER120
LGAANNMFRT  WVFDISGKLK  AGDNELRVVF  DSPTRRGLEE  MKRYGLRLPA  ANDQSERGGM180
GKDRVSVYTR  KAPYHYGWDW  GPRLVTSGIW  RPVLLEAWDG  MKVENVYIRQ  ADISEKLATL240
SADVRVKADE  GQNVEVEVSN  DGKILVAVKE  KLEKGENDIS  VPFDIVNPRL  WWSNGLGEQN300
LYTFTVRVKG  ERGMVAEKEV  TTGLRSLKLV  RKKDQWGESF  GFELNGVPVF  AKGANIIPND360
IFLPRVTPEL  YEKMVADAAN  ANMNMLRVWG  GGIYEDDVFF  ELCDRYGIMV  WHDFMFACAM420
YPGNEEFLNN  VRQEAIDNVV  RLRNHPCIAL  WCGNNENALA  WRHGSPGGWG  WKQQFTKEEQ480
DTVFKAYYDV  FHDLLPRVVD  EYMPGCDYWP  SSPMAGPEPT  QHGLDGTTSG  DQHYWGVWHG540
FRPLESYDEV  TTRFCSEYGF  QSFPEMSTIQ  KYALPEDYDI  DSDVMKSHQR  SYIGNGRISD600
YMEMYYRVPK  DFEQFIYMTH  VLQGLSTKMA  IEAHRRNMPY  CMGSLVWQLN  DCWQVASWST660
TDYYHKWKAA  HYMIRDCFKE  VIVAPKWRND  SLLVYAVSDR  SQPTNAELSV  EVMDFFGKVV720
YAEKADVEVP  ANTSTVLTGR  KRSSLLRGVT  GTDALAVIRL  TSEERVVDEK  NVYFEYHKNL780
NLPKDPGLSI  RVQGEGKEKY  ILVTANKLAC  NVMFALPGGT  AFFSDNYIDI  LPGRTYKINV840
KTELSPTEIE  RQIKYRYLH859

Enzyme Prediction      help

EC 3.2.1.25

CAZyme Signature Domains help

Created with Snap428512817121425730034338642947251555860164468773077381627738GH2
Family Start End Evalue family coverage
GH2 27 738 4e-109 0.6888297872340425

CDD Domains      download full data without filtering help

Created with Snap428512817121425730034338642947251555860164468773077381633838LacZ690779Mannosidase_ig36458ebgA223325Glyco_hydro_2785859Ig_mannosidase
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 4.69e-112 33 838 18 782
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam17786 Mannosidase_ig 1.14e-18 690 779 1 91
Mannosidase Ig/CBM-like domain. This domain corresponds to domain 4 in the structure of Bacteroides thetaiotaomicron beta-mannosidase, BtMan2A. This domain has an Ig-like fold.
PRK10340 ebgA 1.22e-13 36 458 63 451
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam00703 Glyco_hydro_2 6.10e-13 223 325 3 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam17753 Ig_mannosidase 1.09e-08 785 859 1 77
Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.

CAZyme Hits      help

Created with Snap42851281712142573003433864294725155586016446877307738161858QRO49054.1|GH21859AZS28306.1|GH221858SNV29867.1|GH221858ADY31985.1|GH230843CDF80799.1|GH2
Hit ID E-Value Query Start Query End Hit Start Hit End
QRO49054.1 0.0 1 858 1 857
AZS28306.1 0.0 1 859 1 857
SNV29867.1 0.0 21 858 19 850
ADY31985.1 0.0 21 858 19 850
CDF80799.1 9.82e-301 30 843 6 821

PDB Hits      download full data without filtering help

Created with Snap4285128171214257300343386429472515558601644687730773816308382VJX_A308382JE8_A308387OP6_A308382WBK_A308382VQU_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
2VJX_A 9.02e-222 30 838 11 814
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A 9.62e-222 30 838 13 816
Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A 9.93e-222 30 838 13 816
ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A 2.63e-221 30 838 11 814
Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]
2VQU_A 1.15e-219 30 838 11 814
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQU_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron]

Swiss-Prot Hits      download full data without filtering help

Created with Snap428512817121425730034338642947251555860164468773077381630858sp|A2QYN2|MANBB_ASPNC30858sp|Q5B7W2|MANBB_EMENI26858sp|Q0CCA0|MANBB_ASPTN30858sp|Q4WAH4|MANBB_ASPFU30858sp|A1D911|MANBB_NEOFI
Hit ID E-Value Query Start Query End Hit Start Hit End Description
A2QYN2 3.26e-124 30 858 9 842
Beta-mannosidase B OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) OX=425011 GN=mndB PE=3 SV=1
Q5B7W2 9.21e-123 30 858 9 841
Beta-mannosidase B OS=Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) OX=227321 GN=mndB PE=1 SV=2
Q0CCA0 3.72e-121 26 858 5 841
Beta-mannosidase B OS=Aspergillus terreus (strain NIH 2624 / FGSC A1156) OX=341663 GN=mndB PE=3 SV=2
Q4WAH4 1.50e-120 30 858 9 843
Beta-mannosidase B OS=Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) OX=330879 GN=mndB PE=3 SV=1
A1D911 2.93e-120 30 858 9 843
Beta-mannosidase B OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) OX=331117 GN=mndB PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000237 0.090257 0.909363 0.000045 0.000057 0.000048

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003203_00345.