logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000003504_00262

You are here: Home > Sequence: MGYG000003504_00262

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species CAG-1435 sp003537755
Lineage Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-314; CAG-1435; CAG-1435 sp003537755
CAZyme ID MGYG000003504_00262
CAZy Family GH2
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
821 94651.14 5.3995
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003504 2246614 MAG Fiji Oceania
Gene Location Start: 199;  End: 2664  Strand: +

Full Sequence      Download help

MTELRLNKEW  TIDYYGKQLP  AVVPGDVTLD  LWHNNIIDNP  YFGMNHKQLH  WIINRDFVYE60
TRFDVSDEIF  GEQEILLEFI  GINTYVDIYL  NGKQLGHTQN  MFLKYTYSVR  DIVKKSGNLL120
IVKMLSTGRV  MDSIDTRGYH  GVFNVKRLFM  RKAQCHFGWD  WAPDMPGYGI  CGDVRLVGCN180
KNRISDVHYR  AFNNGKLSIF  TDLNYTVREH  MTEDNQLRQC  SPECINDALR  YIVAKRPDEP240
ISDNNCIVFE  TKVSGEKNFA  NFTIENPALW  WPNGYGKQPL  YEYKVQLVRN  GKVADEYVGK300
FAFREVTLCQ  QPYDQTRMQY  QLQINGKNVF  VKGSNWVPAE  CFIGSITTEK  YQRLIGQAAK360
ANFNMLRVWG  GGLYEKDVFY  DICDRNGIMV  WQDFMFACSD  IPEDDAGFVD  ACQKEITYQV420
CRLRNHPSLV  YWCGGNEKTG  SYGLKITKGD  YFVDVILRGT  VDNYDGTRPY  ARQSPCSLTD480
VGNDRTSGES  HAGSYESSLI  SGVLNYRNKV  SESGVMFVSE  CANMGPGTLE  IYKRMFPEDK540
LWPMNEYWRD  RLMENPYSEF  KVPFCERQIL  YADTLYGKSD  TLRQFVAKGM  TSHAESMRAE600
IEFARANPAC  GGFMNWMYSD  IWPSATWAVV  DYYCEPKQAY  YQMKRSYAPI  VVTYVQNEDK660
RLQLVLLNDD  LREVTVDVTY  GMRTLDGKTV  WKHTVTLTSA  GGSAVDIEDK  YNAPDSYLFA720
EYDMDGVKHV  TVFSYDMWHT  CRFASDYTYS  VEKLSECYAV  TIAAKQFAKG  VIVRMKDNYR780
FTYSDNYVDL  QAGEQITLYI  YGATDKDIAT  IEVTDFAKET  A821

Enzyme Prediction      help

EC 3.2.1.25

CAZyme Signature Domains help

Created with Snap41821231642052462873283694104514925335746156566977387795712GH2
Family Start End Evalue family coverage
GH2 5 712 5.5e-90 0.6914893617021277

CDD Domains      download full data without filtering help

Created with Snap41821231642052462873283694104514925335746156566977387796704LacZ30446ebgA250304Glyco_hydro_255452PRK10150748812Ig_mannosidase
Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3250 LacZ 7.98e-52 6 704 15 688
Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10340 ebgA 2.35e-10 30 446 92 456
cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam00703 Glyco_hydro_2 5.66e-09 250 304 55 106
Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK10150 PRK10150 4.34e-06 55 452 61 429
beta-D-glucuronidase; Provisional
pfam17753 Ig_mannosidase 2.20e-04 748 812 5 68
Ig-fold domain. This Ig-like fold domain is found in mannosidase enzymes.

CAZyme Hits      help

Created with Snap41821231642052462873283694104514925335746156566977387791819QHI68839.1|GH219798AQQ71581.1|GH219798AKJ63700.1|GH21705ACK43074.1|GH21722ACI19676.1|GH2|3.2.1.25
Hit ID E-Value Query Start Query End Hit Start Hit End
QHI68839.1 1.45e-173 1 819 1 829
AQQ71581.1 4.81e-166 19 798 38 812
AKJ63700.1 4.51e-131 19 798 28 821
ACK43074.1 1.69e-115 1 705 1 687
ACI19676.1 2.60e-113 1 722 1 703

PDB Hits      download full data without filtering help

Created with Snap418212316420524628732836941045149253357461565669773877917225N6U_A66922VJX_A66922JE8_A66927OP6_A66922WBK_A
Hit ID E-Value Query Start Query End Hit Start Hit End Description
5N6U_A 3.36e-113 1 722 24 726
Crystalstructure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_B Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_C Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12],5N6U_D Crystal structure of Beta-D-Mannosidase from Dictyoglomus thermophilum. [Dictyoglomus thermophilum H-6-12]
2VJX_A 1.70e-95 6 692 11 696
Structuraland biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VJX_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VL4_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VMF_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VO5_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VOT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron VPI-5482],2VQT_A Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VQT_B Structural and biochemical evidence for a boat-like transition state in beta-mannosidases [Bacteroides thetaiotaomicron],2VR4_A Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482],2VR4_B Transition-state mimicry in mannoside hydrolysis: characterisation of twenty six inhibitors and insight into binding from linear free energy relationships and 3-D structure [Bacteroides thetaiotaomicron VPI-5482]
2JE8_A 1.77e-95 6 692 13 698
Structureof a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2JE8_B Structure of a beta-mannosidase from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
7OP6_A 1.81e-95 6 692 13 698
ChainA, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP6_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_A Chain A, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482],7OP7_B Chain B, Beta-mannosidase [Bacteroides thetaiotaomicron VPI-5482]
2WBK_A 4.66e-95 6 692 11 696
Structureof the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482],2WBK_B Structure of the Michaelis complex of beta-mannosidase, Man2A, provides insight into the conformational itinerary of mannoside hydrolysis [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Created with Snap418212316420524628732836941045149253357461565669773877916803sp|I2C092|MANBB_THETO18659sp|Q95327|MANBA_CAPHI18659sp|Q29444|MANBA_BOVIN18658sp|Q4FZV0|MANBA_RAT18659sp|O00462|MANBA_HUMAN
Hit ID E-Value Query Start Query End Hit Start Hit End Description
I2C092 1.08e-78 16 803 23 841
Beta-mannosidase B OS=Thermothelomyces thermophilus OX=78579 GN=man9 PE=1 SV=1
Q95327 4.13e-78 18 659 39 700
Beta-mannosidase OS=Capra hircus OX=9925 GN=MANBA PE=1 SV=1
Q29444 5.36e-77 18 659 39 700
Beta-mannosidase OS=Bos taurus OX=9913 GN=MANBA PE=1 SV=1
Q4FZV0 8.46e-74 18 658 39 699
Beta-mannosidase OS=Rattus norvegicus OX=10116 GN=Manba PE=2 SV=1
O00462 1.04e-72 18 659 39 700
Beta-mannosidase OS=Homo sapiens OX=9606 GN=MANBA PE=1 SV=3

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000044 0.000003 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003504_00262.