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CAZyme Information: MGYG000004144_00234
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Monoglobales; Monoglobaceae; ; | |||||||||||
| CAZyme ID | MGYG000004144_00234 | |||||||||||
| CAZy Family | GH2 | |||||||||||
| CAZyme Description | Beta-glucuronidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1306; End: 3141 Strand: - | |||||||||||
Full Sequence Download help
| MIDAQAMQYP RITKTRRIMD LNGLWKFKFD PDGIGIENNW INGLEDTIAM PVPASFNDFF | 60 |
| TDKGSREYTG DFWYEKEFLV PGEWKGMEIA LRFECATHRA TVYVNGKEIT SHEGGFLPFL | 120 |
| ARIGDVVKFN EVNKVVVKLN NELSFTSLPA GAIKTLKNGV KMAKPFFDFY NYSGLNRAVR | 180 |
| LMAVPKESVL DLAVSHRIIG ADTQTDYEVL TSGENRVRVT VYDRAGEIVA ESEGKRGTIK | 240 |
| IRDTQLWRAL DAYLYIFRIS IESGDGELID EYYEDIGIRT VEVKKREILI NGEPVYLKGF | 300 |
| GKHEDSDVIG RGFSLAVAKR DFELMRWIGA NSFRTSHYPY SEEIMQMADR EGFLVIDEVA | 360 |
| AVGMFESLTN FLDASSGKQT DFFAREIVQT ETRENHIRAL AELIARDKNH ACVIAWSLFN | 420 |
| EPETTSDSAV EYFDDIFKAA RRLDPQKRPR TFALIMNSTP NKCKCHKFTD IIALNRYFGW | 480 |
| YLSGGYELSD AKDTFIEELK KWEEIEPDKP IIFTEFGADT IAGIHKLPSV MWSEEYLKTQ | 540 |
| FEVFDMFDSV KGEQVWNFAD FQTTEGVMRA DGNKKGIFTR SRQPKRAAYL LKDRWKSLPT | 600 |
| DYKSDRRKAS D | 611 |
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH2 | 6 | 594 | 8.3e-97 | 0.6223404255319149 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK10150 | PRK10150 | 0.0 | 7 | 599 | 1 | 596 | beta-D-glucuronidase; Provisional |
| COG3250 | LacZ | 1.08e-94 | 9 | 596 | 1 | 596 | Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]. |
| pfam02836 | Glyco_hydro_2_C | 2.53e-72 | 281 | 595 | 1 | 297 | Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. |
| PRK10340 | ebgA | 8.72e-28 | 3 | 445 | 26 | 468 | cryptic beta-D-galactosidase subunit alpha; Reviewed |
| pfam02837 | Glyco_hydro_2_N | 5.69e-23 | 18 | 185 | 1 | 169 | Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QBE95891.1 | 7.11e-284 | 6 | 605 | 5 | 606 |
| QIB58662.1 | 1.69e-283 | 7 | 605 | 1 | 601 |
| QMW81249.1 | 1.69e-283 | 7 | 605 | 1 | 601 |
| QJU16299.1 | 3.34e-282 | 6 | 604 | 5 | 605 |
| QQQ91196.1 | 3.34e-282 | 6 | 604 | 5 | 605 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7KGY_A | 1.35e-249 | 5 | 605 | 4 | 607 | ChainA, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_B Chain B, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_C Chain C, Beta-glucuronidase [Faecalibacterium prausnitzii],7KGY_D Chain D, Beta-glucuronidase [Faecalibacterium prausnitzii] |
| 6JZ1_A | 2.83e-245 | 9 | 595 | 8 | 596 | Apostructure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ1_B Apo structure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ5_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ5_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ6_A b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ6_B b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_A b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_B b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ8_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus],6JZ8_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus] |
| 5Z18_A | 6.61e-245 | 9 | 595 | 32 | 620 | Thecrystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_B The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_C The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_D The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_E The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z18_F The crystal structure of Ruminococcus gnavus beta-glucuronidase [[Ruminococcus] gnavus],5Z19_A The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_B The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_C The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_D The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_E The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],5Z19_F The crystal structure of Ruminococcus gnavus beta-glucuronidase in complex with uronic isofagomine [[Ruminococcus] gnavus],6JZ2_A b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution [[Ruminococcus] gnavus],6JZ2_B b-glucuronidase from Ruminococcus gnavus in complex with uronic isofagomine at 1.3 Angstroms resolution [[Ruminococcus] gnavus],6JZ3_A b-glucuronidase from Ruminococcus gnavus in complex with uronic deoxynojirimycin [[Ruminococcus] gnavus],6JZ3_B b-glucuronidase from Ruminococcus gnavus in complex with uronic deoxynojirimycin [[Ruminococcus] gnavus],6JZ4_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro-d-lactam [[Ruminococcus] gnavus],6JZ4_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro-d-lactam [[Ruminococcus] gnavus] |
| 6EC6_A | 1.28e-244 | 9 | 595 | 31 | 619 | Ruminococcusgnavus Beta-glucuronidase [[Ruminococcus] gnavus],6EC6_B Ruminococcus gnavus Beta-glucuronidase [[Ruminococcus] gnavus] |
| 6ED2_A | 1.24e-243 | 5 | 607 | 26 | 631 | ChainA, Glycosyl hydrolase family 2, TIM barrel domain protein [Faecalibacterium duncaniae] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P05804 | 8.17e-162 | 7 | 598 | 1 | 591 | Beta-glucuronidase OS=Escherichia coli (strain K12) OX=83333 GN=uidA PE=1 SV=2 |
| O18835 | 1.79e-131 | 7 | 601 | 27 | 631 | Beta-glucuronidase OS=Canis lupus familiaris OX=9615 GN=GUSB PE=1 SV=1 |
| Q4FAT7 | 7.28e-131 | 7 | 601 | 28 | 632 | Beta-glucuronidase OS=Sus scrofa OX=9823 GN=GUSB PE=3 SV=1 |
| O97524 | 3.10e-129 | 7 | 601 | 27 | 631 | Beta-glucuronidase OS=Felis catus OX=9685 GN=GUSB PE=1 SV=1 |
| O77695 | 5.66e-129 | 7 | 596 | 24 | 625 | Beta-glucuronidase (Fragment) OS=Chlorocebus aethiops OX=9534 GN=GUSB PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000044 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |